Pyrimidine nucleosides
Medchemexpress LLC 3′-Deoxyuridine | 7057-27-4 | 98.0% | 228.20 | 100 MG
3′-Deoxyuridine is a potential anticancer and antiviral agent that inhibits bovine diarrhoea virus (BVDV) production.
- Potential anticancer agent.
- Potential antiviral agent.
- Inhibits bovine diarrhoea virus (BVDV) production.
Medchemexpress LLC 2'-Deoxycytidine-5'-monophosphoric acid-13C9,15N3 dilithium | 1032-65-1 | 99.8% | 330.98 | 10 MG
2'-Deoxycytidine-5'-monophosphoric acid-13C9,15N3 dilithium is a 13C and 15N-labeled version of 2'-Deoxycytidine-5'-monophosphoric acid, which is an endogenous metabolite.
- 13C and 15N-labeled compound.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Endogenous metabolite.
- Stable heavy isotopes of hydrogen, carbon, and other elements can be incorporated into drug molecules for quantitation during drug development.
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC 2'-Deoxycytidine-5'-monophosphoric acid (Standard) | 1032-65-1 | 99.6% | 307.20 | 50 MG
2'-Deoxycytidine-5'-monophosphoric acid (Standard) is the analytical standard of 2'-Deoxycytidine-5'-monophosphoric acid. This product is intended for research and analytical applications. 2'-Deoxycytidine-5'-monophosphate is an endogenous metabolite and a deoxynucleotide building block of DNA. It can be used as a substrate of UMP/CMP kinase to form dCDP upon phosphorylation to dCTP, supporting DNA biosynthesis.
- Used as an analytical standard.
- Supports DNA biosynthesis.
- Suitable for qualitative research experiments.
- Suitable for quantitative research experiments.
- Suitable for methodological research experiments in HPLC, GC, and MS.
Selleck Chemical LLC 2-deoxyuridine
2 -deoxyuridine (dU 2 -dU) is frequently halogenated to create thymidine analogues useful for studies of DNA synthesis and degradation mechanisms
Medchemexpress LLC 2'-Deoxyuridine (standard) | 951-78-0 | 99.2% | 5 MG
2'-Deoxyuridine (Standard) is the analytical standard of 2'-Deoxyuridine, intended for research and analytical applications. It is a brain-penetrant pyrimidines nucleotide associated with nervous system diseases. It can increase chromosome breakage and decrease thymidylate synthetase activity. 2'-Deoxyuridine is a precursor in the synthesis of Edoxudine and an analogue of 5-ethynyl-2'-deoxyuridine, EdU. It reduces microglial activation and improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury, making it promising for Alzheimer's disease (AD) research.
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Passes the blood-brain barrier (BBB) in mice.
- Improves cognition and memory loss and attenuates hippocampal damage in Aβ25-35-induced mice models.
Medchemexpress LLC 2'-Deoxyuridine | 951-78-0 | 100.0% | 10 MM 1 ML
2'-Deoxyuridine is a brain-penetrant pyrimidines nucleotide associated with nervous system diseases. It can increase chromosome breakage and decrease thymidylate synthetase activity. It serves as a precursor in the synthesis of Edoxudine and is an analogue of 5-ethynyl-2'-deoxyuridine. Additionally, 2'-deoxyuridine reduces microglial activation and improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury, showing promise for Alzheimer's disease (AD) research.
- Brain-penetrant pyrimidines nucleotide associated with nervous system diseases.
- Increases chromosome breakage.
- Decreases thymidylate synthetase activity.
- Reduces microglial activation.
- Improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury.
- Promising for Alzheimer's disease (AD) research.
Medchemexpress LLC 2'-Deoxycytidine (Standard) | 951-77-9 | MFCD00006547 | 99.95% | 50 MG
2'-Deoxycytidine (Standard) is an analytical standard used as a reference for assays. It is commonly employed in various research experiments, including qualitative, quantitative, and methodological studies.
- Serves as a reference standard for assays.
- Utilized in qualitative research experiments.
- Utilized in quantitative research experiments.
- Utilized in methodological research experiments.
- Applicable in HPLC (High-Performance Liquid Chromatography).
- Applicable in GC (Gas Chromatography).
- Applicable in MS (Mass Spectrometry).
Medchemexpress LLC 2'-Deoxyuridine | 951-78-0 | 99.98% | 50 MG
2'-deoxyuridine is a brain-penetrant pyrimidines nucleotide associated with nervous system diseases. It can increase chromosome breakage and decrease thymidylate synthetase activity. This product is a precursor in the synthesis of Edoxudine and an analogue of 5-ethynyl-2'-deoxyuridine, EdU. It reduces microglial activation and improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury, showing promise for Alzheimer's disease (AD) research.
- Brain-penetrant pyrimidines nucleotide
- Associated with nervous system diseases
- Increases chromosome breakage
- Decreases thymidylate synthetase activity
- Reduces microglial activation and improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury
- Promising for Alzheimer's disease (AD) research
- Appearance: Solid
- Color: White to off-white
Medchemexpress LLC 2'-Deoxycytidine-5'-monophosphate | 1032-65-1 | 100.0% | 307.20 | 500 MG
2'-Deoxycytidine-5'-monophosphate is an endogenous metabolite and a deoxynucleotide building block of which DNA is made. This product can be used as a substrate of UMP/CMP kinase to form dCDP upon phosphorylation to dCTP and supports DNA biosynthesis.
- Endogenous metabolite
- Deoxynucleotide building block for DNA
- Substrate for UMP/CMP kinase
- Supports DNA biosynthesis
Medchemexpress LLC 2'-Deoxycytidine-5'-monophosphoric acid-¹³C₉ (dilithium) | 99.5% | 328.00 | 1 MG
This product is 2'-Deoxycytidine-5'-monophosphate-¹³C₉ (dilithium), an isotopically labeled deoxycytidine monophosphate. It is provided as a colorless to light yellow solution at a concentration of 1 mg (70 mM in 43.55 μL Tris HCl/H₂O buffer pH=7.5). The compound is suitable for research applications requiring a high purity labeled standard.
- Isotopically labeled with ¹³C₉
- High purity of 99.5% (HPLC)
- Isotopic enrichment of 98.9%
- Provided in a solution format
- Recommended for storage at -20°C for up to 2 years