Pyrimidine nucleosides
TARGETMOL CHEMICALS INC 5-FLUORO-2-DEOXYCYTIDINE 50MG
Also available in 2 mg 5 mg 10 mg 25 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 5-Fluoro-2'-deoxycytidine (2'-DEOXY-5-FLUOROCYTIDINE) is an inhibitor of DNA methyltransferase (DNMT) . purity: 99%
Apexbio Technology LLC 5-CHLORO-2-DEOXYURIDINE-100MG
5-Chloro-2 -deoxyuridine (CAS No 50-90-8) is a nucleoside analog commonly used in biomedical research especially in studies related to DNA synthesis and repair mechanisms Originating from modified pyrimidine derivatives it incorporates into DNA and interferes with replication leading to the inhibition of cellular proliferation Its mechanism of action involves targeting the DNA polymerase pathways making it effective in various experimental models In vitro it exhibits activity in the nanomolar to low micromolar range This compound is frequently employed in cancer research particularly in cell culture models and animal studies to assess its potential as a chemotherapeutic agent It s also used in drug screening assays to evaluate novel drug interactions and efficacy Experimental concentrations typically depend on the specific research design allowing flexibility for researchers to tailor their studies according to their unique objectives and model systems
Cayman Chemical 5-Formyl-2-deoxyurIdIn 50mg
A nucleoside derivative; inhibits the proliferation of BHK-21 cells and Ehrlich ascites tumor cells (IC50s = 4 and 6 µM, respectively); reduces virus yield in psuedorabies-infected BHK-21 cells at 1 mM; a product of oxidative DNA damage in vitro
Apexbio Technology LLC 2-Deoxycytidine,1g CAS# 951-77-9
2-Deoxycytidine is a cytidine analog [1]. 2-Deoxycytidine prevents DNA methylation by incorporating itself into newly synthesizing DNA strand. 2-Deoxycytidine also binds to DNA methyltransferase irreversibly and hinders its activity. Thus, 2-deoxycytidine was approved as the most efective demethylating agent for the treatment of cancer [1]. 2-Deoxycytidine at clinically achievable and nontoxic concentrations (≥ 100 μmol/L) protected normal bone marrow progenitor cells against the inhibitory effects of co-administered, high concentrations of 3’-azido-3’-deoxythymidine (AZT) (≥ 10 μmol/L). In normal bone marrow mononuclear cells (BMMC), 2-deoxycytidine also significantly corrected AZT-mediated depletion of intracellular thymidine triphosphate and 2-deoxycytidine triphosphate levels. Furthermore, 2-deoxycytidine reduced the intracellular accumulation of AZT triphosphate and its DNA incorporation in BMMC [2]. Other sizes are also available. Please inqury us for quote.
Apexbio Technology LLC 5-BrdU(Synonyms: Bromodeoxyuridine, BrdU, 5-Bromo-2'-deoxyuridine, 5-Bromodeoxyuridine), 1g, CAS: 59-14-3.
5-Bromo-2 -deoxyuridine (5-BrdU CAS 59-14-3) is a thymidine analog that integrates into DNA during S-phase of cell division Its incorporation facilitates immunodetection via specific monoclonal or polyclonal antibodies In vitro studies show that early application of 5-BrdU to Nicotiana glauca pith explants inhibits cellular proliferation an effect reversed by addition of thymidine or deoxycytidine In vivo BrdU immunostaining identifies proliferating neuronal cells in mouse central nervous system tissues paralleling earlier thymidine labeling studies Thus 5-BrdU serves as a molecular tool for analyzing cell cycle progression and neurogenesis in biomedical research
Medchemexpress LLC 2'-deoxycytidine-5'-triphosphate | 2056-98-6 | MFCD00135938 | 98.2% | 467.16 g/mol | C9H16N3O13P3 | 5 MG
Deoxycytidine triphosphate (dCTP) is a deoxynucleoside triphosphate used as a substrate for DNA polymerases in molecular biology workflows. It supplies the deoxycytidine nucleotide required for enzymatic DNA synthesis and is commonly used in PCR, quantitative PCR, cDNA synthesis, and DNA sequencing.
- High chemical purity (≈98.2%)
- Molecular weight 467.16 g/mol
- Provides deoxycytidine nucleotide for polymerase-catalyzed DNA synthesis
- Suitable for PCR, qPCR, cDNA synthesis, and DNA sequencing
- Available in small lyophilized pack sizes (e.g., 5 mg) for laboratory workflows
- Documented CAS number for unambiguous identification (2056-98-6)
Medchemexpress LLC 3′-Deoxyuridine | 7057-27-4 | 98.0% | 228.20 | 25 MG
3′-Deoxyuridine is a potential anticancer and antiviral agent that inhibits bovine diarrhoea virus (BVDV) production. It is for research use only and appears as a white to light yellow solid.
- Potential anticancer agent
- Potential antiviral agent
- Inhibits bovine diarrhoea virus (BVDV) production
- For research use only
- Appearance: Solid
- Color: White to light yellow
Medchemexpress LLC Deoxycytidine triphosphate | 2056-98-6 | MFCD00135938 | 98.2% | 467.16 g/mol | C9H16N3O13P3 | 50 MG
Deoxycytidine triphosphate (dCTP) is a deoxynucleoside triphosphate used as a substrate for DNA polymerases in molecular biology. Supplied as a laboratory reagent, it is intended for enzymatic DNA synthesis applications such as PCR, cDNA synthesis, and DNA sequencing.
- High purity suitable for enzymatic DNA synthesis and PCR.
- Accurate molecular weight and formula for reagent planning.
- Supplied in a convenient small-scale package for method development.
- Stable when stored under recommended conditions to preserve activity.
- Commonly used as a deoxynucleotide substrate in sequencing and amplification workflows.
Medchemexpress LLC 3′-Deoxyuridine | 7057-27-4 | 98.0% | 228.20 | 1 ML
3′-Deoxyuridine is a potential anticancer and antiviral agent. It has been shown to inhibit bovine diarrhea virus (BVDV) production.
- Potential anticancer agent.
- Potential antiviral agent, inhibiting bovine diarrhea virus (BVDV) production.
![eMolecules 951-78-0 | 2'-Deoxyuridine | ChemScene | MFCD00006527 | 228.204 | C9H12N2O5 | 98.000 | OC[C@H]1O[C@H](C[C@@H]1O)n1ccc(=O)[nH]c1=O | 25g | 572244290](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502484797.JPG-250.jpg)
eMolecules 951-78-0 | 2'-Deoxyuridine | ChemScene | MFCD00006527 | 228.204 | C9H12N2O5 | 98.000 | OC[C@H]1O[C@H](C[C@@H]1O)n1ccc(=O)[nH]c1=O | 25g | 572244290
2'-Deoxyuridine | ChemScene | 951-78-0 | MFCD00006527 | 228.204 | C9H12N2O5 | 98.000 | OC[C@H]1O[C@H](C[C@@H]1O)n1ccc(=O)[nH]c1=O | 25g | 572244290
Cayman Chemical 5-Chloro-2-deoxyurIdIn 25mg
A thymidine analog that is readily incorporated, following phosphorylation, into newly synthesized DNA in place of thymidine; can be detected immunologically in cells and tissues
Medchemexpress LLC 2'-Deoxycytidine-5'-monophosphate | 1032-65-1 | MFCD00006546 | ≥95.0% | 1 G
2'-Deoxycytidine-5'-monophosphate is an endogenous metabolite and a deoxynucleotide building block of DNA. It can be utilized as a substrate for UMP/CMP kinase to form dCDP upon phosphorylation to dCTP, thereby supporting DNA biosynthesis.
- Endogenous metabolite.
- Deoxynucleotide building block of DNA.
- Can be utilized as a substrate for UMP/CMP kinase.
- Supports DNA biosynthesis.
- Related to metabolic disease research.