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One-carbon nitrogen ring bases (thymine and cytosine) covalently linked to a sugar (ribose or deoxyribose) and one to three phosphate groups; can function as extracellular messengers, antimetabolites, and chain terminators that inhibit viral DNA polymerase.
Uridine diphosphate (UDP)-GalNAc acts as a precursor in the biosynthesis of O-linked oligosaccharide. It also acts as a substrate for synthesis of chitin a vital element of cell walls in fungi and of exoskeletons of arthropods and insects.
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UDP-GlcNAz disodium is an analogue of UDP-GlcNAc disodium. It functions as a donor substrate for various N-acetylgalactosaminyltransferases and is a click chemistry reagent with an Azide group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions.
Functions as a sugar donor
Serves as a substrate for OGTase and O-GlcNAcase
Capable of glycosylating p62
Glycosidic bond can be cleaved by O-GlcNAcase catalysis
Useful in research concerning protein glycosylation
Can be incorporated into nuclear proteins in Jurkat cells
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