Drug Standards
Medchemexpress LLC Atovaquone | 95233-18-4 | 366.84 | 1 ML
Atovaquone is a potent, selective, and orally active inhibitor of the parasite's mitochondrial cytochrome bc1 complex. It is effective against human and P. falciparum cytochrome bc1 activity. Atovaquone is an antimalarial agent with potential for investigating pneumocystis pneumonia, toxoplasmosis, malaria, and babesia.
- Potent, selective, and orally active inhibitor
- Targets the Qo site of the Plasmodium cytochrome bc1 complex
- Demonstrates an IC50 of 67 nM for transmission blocking potential
- Improved mice survival rate in animal models
Medchemexpress LLC Haloperidol (standard) | 52-86-8 | MFCD00051423 | 99.84% | C₂₁H₂₃ClFNO₂ | 50 MG
Haloperidol (Standard) is the analytical standard of Haloperidol, intended for research and analytical applications. It is a potent dopamine D2 receptor antagonist, widely used as an antipsychotic. This compound is of analytical standard grade, used as a reference standard for assay.
- Used in qualitative, quantitative and methodological research experiments
- Suitable for HPLC, GC and MS applications
Medchemexpress LLC Milrinone lactate | 100286-97-3 | 98.1% | C12H9N3O.xC3H6O3 | 25 MG
Milrinone lactate is a potent inotropic dilating agent that demonstrates simultaneous positive inotropic and vasodilating activities. It promotes the reduction of Systemic Vascular Resistance (SVR) and Pulmonary Vascular Resistance (PVR) in patients with Dilated Cardiomyopathy (DCM) and NYHA class III and IV heart failure. It has potential for research into cardiovascular function following cardiac surgery and in septic shock.
- Simultaneous positive inotropic and vasodilating activities
- Reduces SVR and PVR in heart failure patients
- Useful for research into cardiovascular function
- Targets phosphodiesterase (PDE)
- For research use only
Medchemexpress LLC Acarbose (Standard) | 56180-94-0 | 99.9% | C25H43NO18 | 25 MG
Acarbose (Standard) is an analytical standard of Acarbose, intended for research and analytical applications. This antihyperglycemic agent is an orally active alpha-glucosidase inhibitor with an IC50 of 11 nM, capable of enhancing the hypoglycemic effects of sulfonylureas or insulin.
- Serves as a reference standard for assays
- Commonly utilized in qualitative, quantitative, and methodological research experiments
- Suitable for techniques such as HPLC, GC, and MS
- Has a molecular weight of 645.60
- Appears as a white to off-white solid
- Initial source is microorganisms
- Structure classified under saccharides and polysaccharides
- Shipped at room temperature in the continental US; conditions may vary elsewhere
Medchemexpress LLC Dicloxacillin sodium | 343-55-5 | 98.0% | 492.31 | C19H16Cl2N3NaO5S | 10 MG
Dicloxacillin sodium is a β-lactam antibiotic of the penicillin class supplied for research and analytical applications. It is active against gram-positive bacteria, including β-lactamase-producing Staphylococcus aureus, and is offered in small milligram quantities for laboratory use.
- β-lactam antibiotic effective against gram-positive bacteria
- 98.0% reported purity
- available in multiple sizes, including 10 MG
- molecular formula C19H16Cl2N3NaO5S; molecular weight 492.31
- CAS number 343-55-5
- intended for research and analytical use
Medchemexpress LLC Enzalutamide (standard) | 915087-33-1 | 100.0% | C21H16F4N4O2S | 25 MG
Enzalutamide (Standard) is the analytical standard of Enzalutamide, intended for research and analytical applications. It acts as an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells and is also an autophagy activator. This analytical standard grade compound serves as a reference for assays, commonly utilized in qualitative, quantitative, and methodological research experiments involving techniques such as HPLC, GC, and MS.
- Analytical standard of enzalutamide
- Intended for research and analytical applications
- Functions as an androgen receptor (AR) antagonist
- Autophagy activator
- Serves as a reference standard for assays
- Utilized in qualitative, quantitative, and methodological research experiments
- Compatible with techniques such as HPLC, GC, and MS
Selleck Chemical LLC RO4929097 5mg 847925-91-1
RO4929097 is a ? secretase inhibitor with IC50 of 4 nM in a cell-free assay, inhibiting cellular processing of A?40 and Notch with EC50 of 14 nM and 5 nM, respectively. Phase 2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC Cpd-1224 | 2891620-68-9 | 99.8% | 855.40 | C43H47ClN8O7S | 10 MG
CPD-1224 is an orally active small-molecule inhibitor of anaplastic lymphoma kinase (ALK) that links an ALK-binding moiety to a cereblon ligand to induce target degradation. It degrades EML4-ALK and resistant mutant forms, shows tumor growth inhibition in preclinical studies, and is supplied for research applications.
- Orally active anaplastic lymphoma kinase (ALK) inhibitor that promotes target degradation.
- Effective against resistance mutations L1196M and G1202R.
- High purity (>99.8%) suitable for analytical and biological assays.
- Soluble in DMSO at approximately 14.29 mg/mL for in vitro studies.
- Available in small-molecule quantities for preclinical research.
Apexbio Technology LLC Atazanavir sulfate (BMS-232632-05) 229975-97-7 5mg
Atazanavir sulfate (BMS-232632-05) (CAS 229975-97-7) is a small-molecule inhibitor targeting HIV-1 protease It is designed to inhibit protease-mediated processing of HIV gag and gag-pol polyproteins thereby blocking viral particle maturation Atazanavir sulfate exerts its biological activity primarily through selective inhibition of HIV-1 protease In in vitro studies atazanavir sulfate demonstrates inhibitory activity against HIV-1 strains with reported IC50 values ranging from 2 to 5 nM Based on these pharmacological properties atazanavir sulfate holds research potential in antiviral studies focused on HIV replication mechanisms and investigations of drug metabolism mediated by hepatic CYP systems
Medchemexpress LLC Des(methylpiperazinyl-N-methyl) imatinib dimer impurity | 1365802-18-1 | MFCD28899574 | 96.1% | C52H48N12O2 | 10MG
Imatinib Impurity E is an analytical reference standard used to characterize and quantify a known impurity of imatinib (CAS 1365802-18-1). Supplied as a high-purity compound (96.05%), it is intended for research and quality-control workflows such as impurity profiling, method development, and stability testing.
- Serves as an analytical reference standard for impurity identification.
- Supports HPLC, LC-MS, and method validation workflows.
- Supplied with a certificate of analysis for traceability.
- High reported purity suitable for quantitative analysis.
- Available in small laboratory pack sizes for analytical use.
Medchemexpress LLC Neratinib (Standard) | 698387-09-6 | 99.3% | 557.04 | 25 MG
Neratinib (Standard) is the analytical standard of Neratinib, intended for research and analytical applications. Neratinib (HKI-272) is an orally available, irreversible, highly selective HER2 and EGFR inhibitor with IC50s of 59 nM and 92 nM, respectively.
- Analytical standard for Neratinib
- Used for research and analytical applications
- Orally available
- Irreversible
- Highly selective HER2 and EGFR inhibitor
- Commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS
Medchemexpress LLC Lidocaine (Standard) | 137-58-6 | 100.0% | 50 MG
Lidocaine (Standard) is the analytical standard of Lidocaine, intended for research and analytical applications. It inhibits sodium channels involving complex voltage and using dependence, and decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. It is an amide derivative and has potential for the research of ventricular arrhythmia.
- Analytical standard for research and analytical applications
- Inhibits sodium channels
- Decreases growth, migration, and invasion of gastric carcinoma cells
- Potential for research of ventricular arrhythmia
- Used in qualitative, quantitative, and methodological research experiments
- Suitable for HPLC, GC, and MS applications
Selleck Chemical LLC Silmitasertib (CX-4945) 10mM/1mL 1009820-21-6
Silmitasertib (CX-4945) is a potent and selective inhibitor of CK2 (casein kinase 2) with IC50 of 1 nM in a cell-free assay, less potent to Flt3, Pim1 and CDK1 (inactive in cell-based assay). Silmitasertib induces autophagy and promotes apoptosis. Phase 1/2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Cayman Chemical N-Despropyl RopInIrole 25mg
An active metabolite of ropinirole; increases extracellular acidification rates in CHO cells expressing human dopamine D2, D3, and D4 receptors (EC50s = 0.63, 0.063, and 1.23 µM, respectively); a potential impurity found in commercial preparations of ropinirole