Drug Standards
Cayman Chemical S S-hydroxy Bupropion hydroc
An active metabolite of bupropion; inhibits dopamine and norepinephrine but not 5-HT reuptake in HEK293 cells expressing the human transporters (IC50s = 0.63, 0.241, and >100 µM, respectively); an antagonist of α3β4-, α4β2-, α4β4-, and α1β1 subunit-containing nAChRs (IC50s = 11, 3.3, 30, and 28 µM, respectively); inhibits nicotine-induced analgesia in the tail-flick and hot plate tests, hyperlocomotion, and hypothermia in mice (ED50s = 0.2, 1, 0.9, and 1.5 mg/kg, respectively); substitutes for (+)-amphetamine in rats in a two-lever drug discrimination test (ED50 = 4.4 mg/kg)
Cayman Chemical N-NItroso Metoprolol 10mg
A genotoxic derivative of metoprolol; induces DNA fragmentation in rat hepatocytes from 0.1-1 mM; induces micronucleation of rat hepatocytes in vivo at 1,000 mg/kg
Cayman Chemical LenalIdomIde 100mg
A derivative of thalidomide; reduces TNF-α production in isolated human PBMCs and whole blood stimulated by LPS from S. minnesota (IC50s = 13 and 25 nM, respectively); has been used as a building block in the synthesis of PROTACs that induce the degradation of IKZF1 and IKZF3 in MM.1S cells; reduces vascularization and total microvascular length in a rat mesenteric window assay model at 250 mg/kg per day, p.o.
Medchemexpress LLC Ticagrelor impurity 25 | 1616703-93-5 | 96.9% | C25H30F2N6O5S | 100 MG
Ticagrelor impurity 25 is an impurity of Ticagrelor. It is for research use only.
- Molecular weight: 564.60
- Appearance: Solid
- Shipping at room temperature in continental US; may vary elsewhere
- Store at 4°C, protect from light
- Store in solvent at -80°C for 6 months or -20°C for 1 month, protecting from light
Medchemexpress LLC Trans-latanoprost | 913258-34-1 | MFCD03411996 | 98.4% | C26H40O5 | 10MG
trans-Latanoprost is the trans isomer of latanoprost (5,6-trans-latanoprost) provided as a research-grade chemical reference for studies of glaucoma and elevated intraocular pressure. It has molecular formula C26H40O5, molecular weight 432.59, and is offered with a reported purity of 98.35% across multiple pack sizes for laboratory use.
- High reported purity (98.35%).
- Characterized for analytical and research applications.
- Applicable to glaucoma and ocular hypertension research.
- Available in multiple lab-friendly pack sizes.
- Provided with analytical characterization data for reproducible results.
Medchemexpress LLC Carboprost tromethamine | 58551-69-2 | 99.85% | C25H47NO8 | 50 MG
Carboprost tromethamine is a synthetic 15-methyl analogue of prostaglandin F2α. It effectively promotes uterine contraction and significantly reduces bleeding during and after delivery. It is for research use only.
- Solid appearance
- White to off-white color
- Shipped at room temperature in continental US; may vary elsewhere
- Sealed storage at 4°C, away from moisture (solid)
- In solvent storage: -80°C for 6 months; -20°C for 1 month (sealed, away from moisture)
- Soluble in DMSO and H2O (100 mg/mL)
Medchemexpress LLC Triprolidine hydrochloride monohydrate | 6138-79-0 | 99.9% | 50 MG
Triprolidine hydrochloride monohydrate is a first-generation antihistamine and an oral active histamine H1 antagonist. It can be used for the research of allergic rhinitis and exhibits spinal motor and sensory block in rats.
- First-generation antihistamine
- Oral active histamine H1 antagonist
- Can be used for allergic rhinitis research
- Exhibits spinal motor and sensory block in rats
Sigma Aldrich Fine Chemicals Biosciences Asiaticoside United States Pharmacopeia (USP) Reference Standard | 16830-15-2 | MFCD06642601 | 30MG
Asiaticoside United States Pharmacopeia (USP) Reference Standard | Mol Wt: 959.12 | 16830-15-2 | MFCD06642601 | 30MG
Medchemexpress LLC (2S)-2-(6-Methoxy-2-naphthyl)propanoic acid sodium salt | 26159-34-2 | C14H13NaO3 | 25 G
Naproxen sodium is a nonsteroidal anti-inflammatory drug (NSAID) and a potent inhibitor of both COX-1 and COX-2 enzymes. It demonstrates anti-inflammatory and antifibrotic effects, downregulating TGF-β levels and Smad3/4 complex formation, and inhibiting pain, fever, and PGE2 time-courses.
- Purity of 99.74%
- White to off-white solid appearance
- Store at 4°C, sealed, away from moisture
- When in solvent, store at -80°C for 6 months or -20°C for 1 month, sealed and away from moisture
- Inhibits COX-1 (IC50 of 9.55 μM in intact cells)
- Inhibits COX-2 (IC50 of 5.65 μM in intact cells)
Sigma Aldrich Fine Chemicals Biosciences Pyridostigmine impurity A European Pharmacopoeia (EP) Reference Standard | 51581-32-9 |
Pyridostigmine impurity A European Pharmacopoeia (EP) Reference Standard | Mol Wt: 166.18 | 51581-32-9 |
Sigma Aldrich Fine Chemicals Biosciences Captopril impurity J European Pharmacopoeia (EP) Reference Standard | 64838-55-7 |
Captopril impurity J European Pharmacopoeia (EP) Reference Standard | Mol Wt: 259.32 | 64838-55-7 |
Sigma Aldrich Fine Chemicals Biosciences Articaine United States Pharmacopeia (USP) Reference Standard | 23964-58-1 | 40MG
Articaine United States Pharmacopeia (USP) Reference Standard | Mol Wt: 284.37 | 23964-58-1 | 40MG
Sigma Aldrich Fine Chemicals Biosciences Methyl parahydroxybenzoate European Pharmacopoeia (EP) Reference Standard | 99-76-3 | MFCD00002352 |
Methyl parahydroxybenzoate European Pharmacopoeia (EP) Reference Standard | Mol Wt: 152.15 | 99-76-3 | MFCD00002352 |
Selleck Chemical LLC Manidipine 2HCl 25mg 89226-75-5 CV-4093
Manidipine 2HCl (CV-4093) is a HCl salt form of Manidipine, which is a calcium channel blocker with IC50 of 2.6 nM, used clinically as an antihypertensive. Phase 4. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Sigma Aldrich Fine Chemicals Biosciences Pimobendan United States Pharmacopeia (USP) Reference Standard | 74150-27-9 | MFCD00761648 | 100MG
Pimobendan United States Pharmacopeia (USP) Reference Standard | Mol Wt: 334.37 | 74150-27-9 | MFCD00761648 | 100MG