Drug Standards
Medchemexpress LLC Afatinib impurity 1 | 2223677-66-3 | 10mg
Afatinib impurity 1 (Afatinib Impurity CSEJXA) is an impurity of Afatinib (HY-10261)
![Medchemexpress LLC 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quin azolinyl], | 2223677-64-1 | 50mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quin azolinyl], | 2223677-64-1 | 50mg
Afatinib impurity 34 is an impurity of Afatinib (HY-10261)
Medchemexpress LLC Bedaquinoline impurity 12 | 2924118-12-5 | 1mg
Bedaquinoline impurity 12 is an impurity of Bedaquinoline
AdipoGen Tamoxifen 10540-29-1, 1 g
Tamoxifen (1 g), AdipoGen Life Sciences. Chemical. CAS: 10540-29-1. Formula: C26H29NO. MW: 371.51. Synthetic. Selective estrogen receptor modulator (SERM) used as adjuvant therapy for estrogen-dependent breast cancer. Antagonist of ER action in breast tissue and breast cancer cells and ER agonist in bone, uterus, and the cardiovasculature system. This prodrug is metabolized by cytochrome P450 (CYP450) enzymes to the active metabolites N-desmethyl-TMX, 4-hydroxy-N-desmethyl-TMX (endoxifen) and 4-hydroxy-TMX (afimoxifene). N,N-Didesmethyl-4-hydroxytamoxifen (norendoxifen), another active metabolite has been found to act as a potent competitive aromatase inhibitor and may also be involved in its antiestrogenic activity. Binds microsomal antiestrogen binding sites, altering cholesterol esterification at therapeutic doses and impacting breast cancer cell differentiation, apoptosis, and autophagy. Protein kinase C (PKC) inhibitor and anti-angiogenetic factor.
Sigma Aldrich Fine Chemicals Biosciences Trehalose United States Pharmacopeia (USP) Reference Standard | 6138-23-4 | MFCD00071594 | 400MG
Trehalose United States Pharmacopeia (USP) Reference Standard | Mol Wt: 378.33 | 6138-23-4 | MFCD00071594 | 400MG
Sigma Aldrich Fine Chemicals Biosciences Levosimendan | 141505-33-1 | MFCD00867135 | 10mg
Levosimendan | Purity: 98% | Mol Wt: 280.28 | 141505-33-1 | MFCD00867135 | 10mg
Medchemexpress LLC Lapatinib ditosylate monohydrate | 388082-78-8 | 100.0% | 50 MG
Lapatinib ditosylate monohydrate is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains. It has demonstrated IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively. This compound is for research use only.
- Potent, orally active inhibitor of ErbB-2 and EGFR tyrosine kinase domains.
- Inhibits receptor autophosphorylation of EGFR and ErbB-2.
- Selectively inhibits proliferation of human tumor cell lines overexpressing EGFR or ErbB-2.
- Induces G1 arrest in HN5 cells.
- Inhibits tumor xenograft growth in vivo.
- Associated with numerous clinical trials for various cancers.
Medchemexpress LLC Ticagrelor impurity 10 | 98.5% | 562.63 g·mol⁻¹ | C26H32F2N6O4S | 10 MG
Ticagrelor impurity 10 is a research-grade impurity of the antiplatelet agent ticagrelor, supplied for analytical reference, impurity profiling, and method development. The material is provided at high stated purity (98.51%) and is characterized by a molecular weight of 562.63 g·mol⁻¹. Small-mass packages are offered for laboratory use, and accompanying documentation (SDS, COA) is available.
- Research-grade impurity for analytical and QC applications.
- High stated purity (98.51%) for reliable reference standards.
- Available in small milligram quantities suitable for method development.
- Characterized molecular weight for analytical confirmation.
- SDS and COA available to support safe handling and verification.
Medchemexpress LLC Sumatriptan succinate | 103628-48-4 | 99.9% | 413.49 g/mol | C18H27N3O6S | 10 MG
Sumatriptan succinate is an orally active 5-HT1 receptor agonist commonly used in migraine and serotonin receptor research. The compound is supplied as a white to off-white solid with high purity and useful aqueous solubility, and it is intended for analytical and pharmacological studies.
- High purity: 99.89%.
- Molecular weight: 413.49 g/mol.
- Chemical formula: C18H27N3O6S.
- Cas number: 103628-48-4.
- Appearance: white to off-white solid.
- Solubility: H2O ≥ 100 mg/mL; DMSO 50 mg/mL (may require ultrasonic).
- Storage: solid at 4°C; in solvent -80°C up to 6 months, -20°C up to 1 month.
- Applications: migraine and 5-HT1 receptor pharmacology research.
Abcam 25-Hydro x yvitamin D3 (Calcifediol), metabolite of vitamin D3, 5MG
MW 400.6 Da, Purity >98%. Principal cholecalciferol (ab143594) metabolite. Downregulates TLR4 and JAK1/STAT3 signaling. Hydroxylates to calcitriol (ab141456) *in vivo*. Anti-inflammatory effects. Orally active.
The product is subject to the following: Abcam Restricted Use Statement