Drug Standards
Cayman Chemical EthacrynIc AcId 5g
A loop diuretic with anticancer activity; inhibits the NKCC cotransporter in duck erythrocytes (IC50 = 0.18 mM); inhibits ATP-dependent chloride uptake in rat renal plasma membrane vesicles at 0.3 mM; inhibits GSTP1-1 and GSTA3-3 (IC50s = 4.9 and ~0.4 μM, respectively); inhibits Wnt/β-catenin signaling in a cell-based reporter assay; cytotoxic to primary chronic lymphocytic leukemia cells (IC50 = 8.56 μM), as well as MCF-7, MDA-MB-231, and 4T1 cancer cells (IC50s = 45.53, 39.64, and 25.23 μM, respectively); increases tumor growth reduction induced by afatinib or neratinib in a 4T1 murine breast cancer model at 250 μg per day
Selleck Chemical LLC Tenofovir S1401-1g
Tenofovir (GS-1278) blocks reverse transcriptase and hepatitis B virus infections
Sigma Aldrich Fine Chemicals Biosciences Miconazole United States Pharmacopeia (USP) Reference Standard | 22916-47-8 | 200MG
Miconazole United States Pharmacopeia (USP) Reference Standard | Mol Wt: 416.13 | 22916-47-8 | 200MG
Sigma Aldrich Fine Chemicals Biosciences Bumetanide impurity A European Pharmacopoeia (EP) Reference Standard | 28328-53-2 |
Bumetanide impurity A European Pharmacopoeia (EP) Reference Standard | Mol Wt: 338.29 | 28328-53-2 |
Sigma Aldrich Fine Chemicals Biosciences Trimeprazine tartrate United States Pharmacopeia (USP) Reference Standard | 4330-99-8 | 200MG
Trimeprazine tartrate United States Pharmacopeia (USP) Reference Standard | Mol Wt: 373.49 | 4330-99-8 | 200MG
Medchemexpress LLC N4-(3,4-dichlorophenyl)-7-methoxyquinazoline-4,6-diamine | 2803451-99-0 | 50mg
Dacomitinib impurity 12 is an impurity of Dacomitinib (HY-13272)
TARGETMOL CHEMICALS INC Metoclopramide 500MG
Also available in 1 mL, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Metoclopramide (5-Chloro-2-methoxyprocainamide) is a dopamine D2 antagonist which has been used for treatment of a variety of gastrointestinal symptoms over the last thirty years. In various countries, metoclopramide is the antiemetic drug of choice in pregnant women. Findings provide reassurance regarding the safety of metoclopramide for the fetus when the drug is given to women to relieve nausea and vomiting during pregnancy. Evidence also supports its use for gastroparesis (poor stomach emptying) and gastroesophageal reflux disease. It appears to bind to dopamine D2 receptors where it is a receptor antagonist, and is also a mixed 5-HT3 receptor antagonist/ 5-HT4 receptor agonist. Purity 99.81%
Selleck Chemical LLC Prexasertib HCl (LY2606368) 25mg 1234015-54-3
Prexasertib (LY2606368) is an ATP-competitive CHK1 inhibitor with a Ki value of 0.9 nmol/L. For CHK2 and RSK, its IC50 values are 8 nM and 9 nM respectively in cell-free assay. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC Loxapine | 1977-10-2 | 99.9% | 327.81 | 500 MG
Loxapine is an orally active dopamine inhibitor, 5-HT receptor antagonist, and a dibenzoxazepine anti-psychotic agent. This compound has been shown to reduce IL-1β and IL-2 secretion by LPS-activated mixed glia cultures, and to decrease serotonin (S2) receptor density in the rat brain without elevating dopamine (D2) receptor numbers.
- Orally active dopamine inhibitor
- 5-HT receptor antagonist
- Dibenzoxazepine anti-psychotic agent
- Reduces IL-1β and IL-2 secretion in glia cultures
- Decreases serotonin (S2) receptor density in rat brain
- Targets human 5-HT2, D4, D1, D2 receptors
- Purity of 99.93%
- Molecular weight of 327.81
- Appears as a light yellow to yellow solid
Selleck Chemical LLC Alibendol 50mg 26750-81-2 EB 1856
Alibendol (EB 1856) is an antispasmodic,choleretic, and cholekinetic. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC Flurbiprofen | 5104-49-4 | MFCD00079303 | 100.0% | 244.26 g/mol | C15H13FO2 | 1 G
Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID) supplied as a research reagent and cyclooxygenase (COX) inhibitor. It is used in biochemical and pharmacological studies of inflammation, pain, and prostaglandin-mediated signaling.
- High purity (99.98%).
- Solid, white to light yellow appearance.
- Molecular weight 244.26 g/mol.
- Chemical formula C15H13FO2.
- Contains CAS number 5104-49-4 for substance identification.
- Available in 1 g and larger solid pack sizes for laboratory use.
- Suitable for in vitro COX inhibition and pharmacology assays.
Cayman Chemical Etofenamate 100mg
An NSAID and diethylene glycol ester form of flufenamic acid; inhibits lipoxygenase isolated from guinea pig leukocytes (IC50 = 5.3 μM) and production of PGE2 in stimulated rat peritoneal macrophages; reduces acetic acid-induced vascular permeability in mice and UV-induced erythema in guinea pigs in a dose-dependent manner at doses ranging from 40-320 and 5-20 mg/kg, respectively; inhibits inflammation in a rat model of adjuvant-induced arthritis; decreases the pain response in a silver nitrate-induced rat model of arthritis and the acetic acid-induced writhing test in mice, indicating analgesic activity
U.S. Pharmacopeia Cetirizine dihydrochloride, 83881-52-1, MFCD00941428, 250 mg
Empirical Formula (Hill Notation): C21H25ClN2O3 · 2HCl, Molecular Weight: 461.81, Synonym: [2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride.
Selleck Chemical LLC Proguanil HCl(Atovaquone) S3082-10mg
Proguanil hydrochloride(Chloroguanil Chlorguanide hydrochloride) an antimalarial proagent acts as an inhibitor of dihydrofolate reductase (DHFR) Proguanil acts as a biguanide to enhance the Atovaquone effect
Sigma Aldrich Fine Chemicals Biosciences Casticin United States Pharmacopeia (USP) Reference Standard | 479-91-4 | MFCD00210481 | 25MG
Casticin United States Pharmacopeia (USP) Reference Standard | Mol Wt: 374.34 | 479-91-4 | MFCD00210481 | 25MG