Carbon Oxygen Demand Standards
Med Vet International Merck, Resflor Gold, 300mg/mL, 500mL
VET LICENSE NEEDS TO BE PROVIDED IN 3-4 BUSINESS DAYS OR ORDER WILL BE CANCELLED
(Florfenicol and Flunixin Meglumine) A simple bovine respiratory disease (BRD) treatment strategy. It involves a combination of two therapies in one dose: The powerful antibiotic florfenicol to kill or inhibit the disease-causing bacteria mannheimia haemolytica, pasteurella multocida, histoophilus somni, and mycoplama bovis. The fast-acting non-steroidal anti-inflammatory drug (NSAID) flunixin meglumine to reduce BRD-associated fever.
Hach Company COD Standard Solution, 300 mg/L as COD (NIST), 500 mL
For accuracy checks in Chemical Oxygen Demand (COD) determinations. 500 mL bottle
TARGETMOL CHEMICALS INC DESCHLOROCLOZAPINE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Deschloroclozapine a metabolite of Clozapine is a highly potent muscarinic DREADDs agonist. Deschloroclozapine binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM respectively. purity: 99%
Apexbio Technology LLC PTP Inhibitor I 2491-38-5 10g
PTP Inhibitor I (CAS 2491-38-5) is a small molecule inhibitor targeting protein tyrosine phosphatases (PTPs) specifically SHP-1 and PTP1B with inhibition constants (KI) of 43 M and 42 M respectively As an -bromoacetophenone derivative it acts as a neutral phosphotyrosine mimetic covalently modifying the active site cysteine of PTPs Structure-activity studies indicate that modifications to the phenyl ring moderately affect potency while para-substituted peptidyl groups can enhance both potency and selectivity PTP Inhibitor I is utilized in vitro for mechanistic studies of PTP function related to diabetes neurodegenerative disorders immune regulation and pathogen virulence Animal and clinical data are not available
Apexbio Technology LLC Docosanol (Abreua) 661-19-8 10g
Docosanol Abreua (CAS 661-19-8) is a small-molecule inhibitor targeting herpes simplex virus (HSV) It is designed to inhibit viral entry processes thereby preventing HSV replication at the initial stage of infection Docosanol Abreua exerts its biological activity primarily through the inhibition of viral envelope fusion with host cell membranes In cell-based studies Docosanol Abreua demonstrates antiviral inhibition with an IC50 value typically in the range of approximately 2 5-5 M Based on these pharmacological properties Docosanol Abreua holds research potential in antiviral mechanism studies investigation of viral entry pathways and host pathogen interaction assays
Apexbio Technology LLC L-Acetylcarnitine (hydrochloride) 5080-50-2 10g
L-Acetylcarnitine (hydrochloride) (CAS 5080-50-2) an acetylated derivative of L-carnitine facilitates the mitochondrial uptake of acetyl-CoA supporting fatty acid oxidation and energy metabolism It enhances acetylcholine synthesis and contributes to membrane phospholipid and protein production In vitro L-acetylcarnitine reduces SKOV-3 ovarian cancer cell proliferation at higher concentrations without affecting CA-125 or nerve growth factor receptor expression In vivo studies demonstrate its rapid and sustained antidepressant-like activity in rodent models linked to epigenetic upregulation of mGlu2 (Grm2) receptors L-acetylcarnitine is utilized in research focusing on metabolism neurobiology and psychiatric disorders
Apexbio Technology LLC Uniconazole 83657-22-1 10g
Uniconazole (CAS 83657-22-1) is a small-molecule inhibitor of cytochrome P450 707A enzymes (CYP707As) which are involved in the catabolism of abscisic acid (ABA) via 8 -hydroxylation In in vitro assays uniconazole demonstrated potent inhibition of CYP707A3 activity with a reported Ki of 68 nM surpassing other plant growth retardants such as paclobutrazol and tetcyclacis In Arabidopsis models uniconazole treatment elevated endogenous ABA levels and enhanced drought tolerance effects that were independent of gibberellin-mediated pathways Uniconazole is therefore utilized in plant biology research to study ABA metabolism and stress responses
Apexbio Technology LLC Diclofenac Potassium 15307-81-0 10g
Diclofenac potassium (CAS 15307-81-0) is a synthetic small molecule belonging to the nonsteroidal anti-inflammatory drug (NSAID) class It functions primarily by inhibiting cyclooxygenase (COX) enzymes thereby reducing the synthesis of prostaglandins involved in inflammation and nociception Through this mechanism diclofenac potassium attenuates inflammatory responses and mediates analgesic effects It is frequently utilized in biomedical research to study inflammatory pathways investigate mechanisms of pain modulation and evaluate anti-inflammatory interventions in cellular and preclinical models
Apexbio Technology LLC Tolfenamic Acid 13710-19-5 10g
Tolfenamic acid (CAS 13710-19-5) is a non-steroidal anti-inflammatory drug (NSAID) that functions primarily through the inhibition of cyclooxygenase (COX) enzymes resulting in reduced prostaglandin synthesis and inflammation In cellular studies tolfenamic acid has been observed to inhibit cell proliferation and promote apoptosis as indicated by heightened caspase activity and alterations in bioelectric impedance measurements These findings support its utility in research investigating inflammatory pathways apoptosis induction and the cellular effects of NSAIDs in various biological systems
Hach Company COD Standard Solution, 1000 mg/L as COD (NIST), 200 mL
For accuracy checks in Chemical Oxygen Demand determinations. 200 mL bottle
Apexbio Technology LLC Bismuth Subsalicylate 14882-18-9 10g
Bismuth subsalicylate (CAS 14882-18-9) is a small molecule compound clinically employed in the management of gastrointestinal disturbances including diarrhea heartburn indigestion and nausea Its pharmacological activity involves a dual mechanism the bismuth component exerts antimicrobial and protective effects on the gastrointestinal mucosa while the salicylate moiety inhibits intestinal prostaglandin synthesis thereby reducing inflammation and intestinal secretions Bismuth subsalicylate is utilized in biomedical research to investigate gastrointestinal barrier function host microbe interactions and inflammatory pathways relevant to digestive disorders
Apexbio Technology LLC Tioconazole 65899-73-2 10g
Tioconazole (65899-73-2) is a small-molecule inhibitor targeting the fungal cytochrome P450-dependent enzyme lanosterol 14 -demethylase It is designed to inhibit ergosterol biosynthesis thereby disrupting fungal cell membrane stability and cellular integrity Tioconazole exerts its biological activity primarily through interference with ergosterol biosynthesis within fungal cell membranes In in vitro studies Tioconazole demonstrates inhibitory activity with MIC50 values below 3 12 mg/L for dermatophyte strains and below 9 mg/L for yeast species Based on these pharmacological properties Tioconazole holds research potential in the study of antifungal mechanisms and in vitro antifungal screening assays
Apexbio Technology LLC Metronidazole Benzoate 13182-89-3 10g
Metronidazole Benzoate (13182-89-3) is a small-molecule inhibitor targeting microbial DNA synthesis It is designed to inhibit nucleic acid synthesis processes thereby disrupting microbial cellular function Metronidazole Benzoate exerts its biological activity primarily through inhibition of nucleic acid synthesis and function within microbial cells In in vitro studies its efficacy is often quantified by IC50 values reflecting the concentration required to achieve half-maximal inhibition of microbial growth Based on these pharmacological properties Metronidazole Benzoate holds research potential in investigations of treatments for bacterial and protozoal infections
Apexbio Technology LLC Amoxicillin 26787-78-0 10g
Amoxicillin (26787-78-0) is a small-molecule inhibitor targeting bacterial penicillin-binding proteins (PBPs) It is designed to disrupt bacterial cell wall biosynthesis thereby impairing peptidoglycan cross-linking and compromising cell wall integrity Amoxicillin exerts its biological activity primarily through inhibition of PBPs interfering with the processes critical to bacterial cell wall formation In in vitro studies Amoxicillin demonstrates inhibitory activity with IC50 values ranging from 0 1 to 5 g/mL depending on experimental conditions and organism susceptibility Based on these pharmacological properties Amoxicillin holds research potential in studies of bacterial infection mechanisms antimicrobial responses and resistance development
Apexbio Technology LLC Arbutin 497-76-7 10g
Arbutin (CAS 497-76-7) is a naturally occurring glycosylated hydroquinone primarily isolated from bearberry (Arctostaphylos uva-ursi) leaves It acts as a competitive inhibitor of tyrosinase an enzyme central to melanin biosynthesis thereby modulating pigment production in biological systems Arbutin is extensively studied in cellular and biochemical assays investigating melanogenesis oxidative stress and potential antimelanogenic therapies Its ability to regulate melanin synthesis has made it a valuable research tool in dermatology cosmetic science and pharmacological studies focused on hyperpigmentation and related disorders The compound should be stored in a sealed cool and dry environment to maintain stability