Acetylides

Medchemexpress LLC Propargyl-PEG12-OH 500mg | 1036204-61-1 | 584.69 | C27H52O13 | 500 MG

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Propargyl-PEG12-OH is a polyethylene glycol (PEG) based linker bearing a terminal propargyl (alkyne) group and a free hydroxyl terminus. It is designed for click chemistry and linker construction in PROTAC synthesis, bioconjugation, and medicinal chemistry, providing a flexible 12-unit PEG spacer with a reactive handle for conjugation.

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eMolecules​ 1159512-64-7 | 2-Fluoro-3-(trifluoromethoxy)aniline | MFCD11975313 | 1g

ChemScene | (R)-1-(26-Difluorophenyl)ethanamine | 100mg | 632323934 | CS-0158209 | 1217453-91-2 | MFCD06761844 | 157.164 | C8H9F2N

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eMolecules​ 106-96-7 | Propargyl bromide (80% wt.in toluene) contains 0.3% magnesium oxide as stabilizer | Oakwood Chemical211.102 | C10H11Br | 0.000 | BrCC#C.Cc1ccccc1 | 10g | 537712115

Propargyl bromide (80% wt.in toluene) contains 0.3% magnesium oxide as stabilizer | Oakwood Chemical | 106-96-7211.102 | C10H11Br | 0.000 | BrCC#C.Cc1ccccc1 | 10g | 537712115

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eMolecules​ 2197502-05-7 | 3-Methoxybicyclo[1.1.1]pentan-1-amine hydrochloride | Combi-Blocks | MFCD30489933 | 149.620 | C6H12ClNO | 97.000 | Cl.COC12CC(N)(C1)C2 | 1g | 517099192

3-Methoxybicyclo[1.1.1]pentan-1-amine hydrochloride | Combi-Blocks | 2197502-05-7 | MFCD30489933 | 149.620 | C6H12ClNO | 97.000 | Cl.COC12CC(N)(C1)C2 | 1g | 517099192

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eMolecules​ 1826900-79-1 | 3-Fluorobicyclo[1.1.1]pentan-1-amine hydrochloride | Combi-Blocks, Inc. | MFCD28963742 | 137.580 | C5H9ClFN | 98.000 | Cl.NC12CC(F)(C1)C2 | 10g | 882683785

3-Fluorobicyclo[1.1.1]pentan-1-amine hydrochloride | Combi-Blocks, Inc. | 1826900-79-1 | MFCD28963742 | 137.580 | C5H9ClFN | 98.000 | Cl.NC12CC(F)(C1)C2 | 10g | 882683785

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Medchemexpress LLC Propanoic acid, 3-[2-[[2-(2-propyn-1-yloxy)ethyl]dithio]ethoxy]- | 1807503-85-0 | ≥95.0% | 264.36 g/mol | C10H16O4S2 | 50 MG

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Cleavable two-unit polyethylene glycol (PEG) linker with a terminal propargyl (alkyne) group for click chemistry and antibody-drug conjugate (ADC) synthesis. It contains a reducible disulfide linkage and is suitable for copper-catalyzed azide-alkyne cycloaddition (CuAAC). Supplied with ≥95.0% purity; molecular weight 264.36 g/mol; CAS 1807503-85-0.

• Cleavable disulfide linker enabling cytosolic release
• Terminal alkyne for copper-catalyzed azide-alkyne cycloaddition
• Two-unit PEG spacer improves solubility and linker flexibility
• High purity suitable for conjugation reactions
• Available in multiple package sizes for research use

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Medchemexpress LLC Propargyl-PEG8-Boc | 2055014-96-3 | 250 MG

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Propargyl-PEG8-Boc is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Alkyne group that allows it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• PEG-based PROTAC linker
• Used in the synthesis of PROTACs
• Click chemistry reagent
• Contains an alkyne group
• Capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
• Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins

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Medchemexpress LLC Propargyl-PEG8-NH2 | 1196732-52-1 | MFCD28334507 | >98.0% | 407.50 g/mol | C19H37NO8 | 50 MG

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Propargyl-PEG8-NH2 is a heterobifunctional PEG8 linker featuring a terminal propargyl (alkyne) group and a primary amine; it is used for click chemistry (CuAAC) and amine derivatization in bioconjugation workflows such as PROTAC and ADC synthesis.

• Contains terminal propargyl (alkyne) group for copper-catalyzed azide-alkyne cycloaddition.
• Contains a primary amine for further derivatization and amide or carbamate coupling.
• Formula C19H37NO8 and molecular weight 407.50 g/mol.
• High purity, specified as ≥98.0%.
• Common applications include ADC linkers, PROTAC linkers, and general bioconjugation building blocks.
• CAS number 1196732-52-1 for chemical identification.

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Biotium Reactive Dyes Biotin Cell Viability and Apoptosis Cellular Stains ViaTag 740 765 1/EA

ViaTag 740/765 Haloalkane Ligand is a bright fluorescent ligand for the HaloTag self-labeling protein tag Near-infrared fluorescent ViaTag 740/765 is cell impermeant and has an excitation/emission of 742/767 nm 30 uL of 1000X

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Apexbio Technology LLC VX-765 273404-37-8 10mM (in 1mL DMSO)

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VX-765 (CAS 273404-37-8) is an orally bioavailable prodrug of VRT-043198 a selective inhibitor targeting caspase-1 (also known as IL-1 converting enzyme ICE) Caspase-1 plays a pivotal role in processing pro-inflammatory cytokines specifically converting inactive precursors of IL-1 and IL-18 into bioactive forms VX-765 downstream metabolite VRT-043198 selectively reduces the secretion of IL-1 and IL-18 in stimulated human peripheral blood mononuclear cells without affecting release of other cytokines such as IL-6 or TNF- Preclinical studies demonstrate VX-765 activity in mouse models of arthritis dermatitis and HIV-associated CD4 T-cell death indicating utility in inflammatory and immunological research

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Medchemexpress LLC Propargyl-PEG3-amine | 932741-19-0 | ≥98.0% | 187.24 | 50 MG

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Propargyl-PEG3-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, possessing an alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups. PROTACs use the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

• PEG-based PROTAC linker
• Click chemistry reagent
• Contains an alkyne group for CuAAc reactions with azide groups

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eMolecules​ 1066-54-2 | Ethynyltrimethylsilane | AA Blocks LLC | MFCD00008569 | 98.220 | C5H10Si | 0.000 | C[Si](C)(C)C#C | 100g | 410166968

Ethynyltrimethylsilane | AA Blocks LLC | 1066-54-2 | MFCD00008569 | 98.220 | C5H10Si | 0.000 | C[Si](C)(C)C#C | 100g | 410166968

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eMolecules​ 76114-73-3 | Propargyl Butylcarbamate | Toronto Research Chemicals | MFCD06411065 | 155.197 | C8H13NO2 | 95.000 | CCCCNC(=O)OCC#C | 500mg | 483432557

Propargyl Butylcarbamate | Toronto Research Chemicals | 76114-73-3 | MFCD06411065 | 155.197 | C8H13NO2 | 95.000 | CCCCNC(=O)OCC#C | 500mg | 483432557

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Medchemexpress LLC 4-Ethynylaniline | 14235-81-5 | 117.15 | 1 ML

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4-Ethynylaniline is a biochemical reagent used in life science research. It serves as a click chemistry reagent, specifically containing an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups.

• Used as a biochemical reagent
• Utilized in life science research
• Functions as a click chemistry reagent
• Contains an alkyne group
• Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
• Reacts with azide-containing molecules

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eMolecules​ 177596-38-2 | 3-Fluoro-4-(trifluoromethoxy)phenol | Apollo Scientific | MFCD06660342 | 196.101 | C7H4F4O2 | 95.000 | Oc1ccc(OC(F)(F)F)c(F)c1 | 1g | 562451566

3-Fluoro-4-(trifluoromethoxy)phenol | Apollo Scientific | 177596-38-2 | MFCD06660342 | 196.101 | C7H4F4O2 | 95.000 | Oc1ccc(OC(F)(F)F)c(F)c1 | 1g | 562451566

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