Acetylides
Medchemexpress LLC N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) | 2112732-01-9 | 519.58 | 25 MG
N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) is a PEG-based PROTAC linker. It is utilized in the synthesis of PROTACs and acts as a click chemistry reagent. This linker contains an alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules that possess azide groups.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Acts as a click chemistry reagent
- Contains an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
Medchemexpress LLC Propargyl-PEG3-methane | 89635-82-5 | 98.0% | 202.25 | 25 G
Propargyl-PEG3-methane is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules possessing Azide groups. For research use only. Not sold to patients.
- Click chemistry reagent
- Alkynes
- PROTAC synthesis
- PROTAC linkers
- Used in cancer research
- Applied in cancer targeted therapy
Medchemexpress LLC 4,7,10,13,16,19-hexaoxadocos-21-ynoic acid | 1951438-84-8 | MFCD28950778 | >=97.0% | 348.39 | C16H28O8 | 25 MG
Propargyl-PEG6-acid is a polyethylene glycol (PEG6) linker bearing a terminal propargyl (alkyne) and a terminal carboxylic acid. It is used as a click-chemistry reagent for copper-catalyzed azide-alkyne cycloaddition (CuAAC) and as a linker in the synthesis of antibody-drug conjugates (ADCs) and proteolysis-targeting chimeras (PROTACs).
- Contains a terminal alkyne for CuAAC click reactions.
- Terminal carboxylic acid enables amide coupling and conjugation.
- Molecular weight 348.39; chemical formula C16H28O8.
- Suitable for use as an ADC and PROTAC linker in bioconjugation workflows.
- Recommended storage: pure material at -20°C for long-term stability.
Medchemexpress LLC Propargyl-PEG2-Tos | 145916-41-2 | MFCD29764327 | >98.0% | C12H14O4S | 100 MG
Propargyl-PEG2-Tos is a laboratory chemical often used as a PROTAC linker for research applications. This compound is stable under recommended storage conditions. While essential for certain laboratory procedures, it is important to note that it may cause skin irritation, serious eye irritation, and respiratory irritation, requiring careful handling. It boasts a high purity of greater than 98.0%.
- Stable under recommended storage conditions
- May cause skin and serious eye irritation
- May cause respiratory irritation
- Suitable for laboratory use
- For research use only
- Purity greater than 98.0%
eMolecules 4-(Propargylaminocarbonyl)phenylboronic acid pinacol ester | 1218790-49-8 | MFCD11113041 | 1g
Combi-Blocks | 4-(Propargylaminocarbonyl)phenylboronic acid pinacol ester | 1g | 117546930 | PN-9139 | 96.000 | 1218790-49-8 | MFCD11113041 | 285.150 | C16H20BNO3
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Medchemexpress LLC VQW-765 | 669770-29-0 | MFCD28502153 | 99.6% | 294.39 g/mol | C19H22N2O | 10 MG
VQW-765 is an orally active, selective partial agonist of the α7 nicotinic acetylcholine receptor (α7-nAChR) developed for preclinical research into anxiety and related CNS disorders. Supplied as a pre-weighed 10 mg research reagent, it is intended for use in in vitro and in vivo studies and is not for human consumption.
- Selective α7 nicotinic acetylcholine receptor partial agonist.
- Orally active compound suitable for in vivo dosing.
- High chemical purity (approximately 99.6%).
- Supplied as a pre-weighed 10 mg quantity for dosing convenience.
- Appropriate for both in vitro and in vivo pharmacology studies.
- Research use only; not for human or clinical use.
eMolecules ChemScene / 4-Bromo-2-ethynylaniline / 100mg / 788449332 / CS-0647038 / 0.000 / 1260776-51-9 / MFCD11036454 / 196.047 / C8H6BrN
ChemScene / 4-Bromo-2-ethynylaniline / 100mg / 788449332 / CS-0647038 / 0.000 / 1260776-51-9 / MFCD11036454 / 196.047 / C8H6BrN
eMolecules Broadpharm / Bis-propargyl-PEG10 / 250mg / 296213608 / BP-22828 / 98.000 / 1351373-47-1 / MFCD28976686 / 490.590 / C24H42O10
Broadpharm / Bis-propargyl-PEG10 / 250mg / 296213608 / BP-22828 / 98.000 / 1351373-47-1 / MFCD28976686 / 490.590 / C24H42O10
eMolecules AstaTech / METHYL 5-ETHYNYLPYRIDINE-2-CARBOXYLATE / 1g / 222802523 / 24407 / 95.000 / 17880-61-4 / MFCD13189756 / 161.160 / C9H7NO2
AstaTech / METHYL 5-ETHYNYLPYRIDINE-2-CARBOXYLATE / 1g / 222802523 / 24407 / 95.000 / 17880-61-4 / MFCD13189756 / 161.160 / C9H7NO2
Medchemexpress LLC 4,7,10,13,16,19,22-heptaoxapentacos-24-ynoic acid | 2093154-00-6 | MFCD30536167 | 98.0% | 392.44 g·mol-1 | C18H32O9 | 50 MG
Propargyl-PEG7-acid is a polyethylene glycol (PEG)-based linker with a terminal propargyl (alkyne) group and a carboxylic acid. It is used as a click-chemistry compatible linker for assembling PROTACs and antibody-drug conjugates, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAC) to attach payloads or targeting moieties.
- Cleavable PEG linker suitable for PROTAC and ADC synthesis.
- Contains a terminal alkyne for CuAAC (click chemistry) conjugation.
- High purity supports reliable coupling reactions.
- Stable as a dry powder when stored under inert atmosphere at low temperature.
- Available in small research packs for medicinal chemistry use.
eMolecules 3-Ethoxy-5-(trifluoromethoxy)phenylboronic acid | 1256345-87-5 | MFCD16295059 | 1g
Combi-Blocks | 3-Ethoxy-5-(trifluoromethoxy)phenylboronic acid | 1g | 117524556 | BB-6330 | 97.000 | 1256345-87-5 | MFCD16295059 | 249.980 | C9H10BF3O4
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Medchemexpress LLC Propargyl-PEG3-bromide | 203740-63-0 | 97.7% | 251.12 | 500 MG
Propargyl-PEG3-bromide is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with azide-containing molecules.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
eMolecules Ambeed / 4-Ethynylaniline / 250mg / 552610097 / A168204 / / 14235-81-5 / MFCD00168824 / 117.151 / C8H7N
Ambeed / 4-Ethynylaniline / 250mg / 552610097 / A168204 / / 14235-81-5 / MFCD00168824 / 117.151 / C8H7N