Acetylides
eMolecules Propargyl-PEG6-alcohol | 1036204-60-0 | MFCD27635181 | 1g
Broadpharm | Propargyl-PEG6-alcohol | 1g | 229582392 | BP-22010 | 98.000 | 1036204-60-0 | MFCD27635181 | 276.329 | C13H24O6
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Medchemexpress LLC Propargyl-PEG1-bromide | 18668-74-1 | MFCD00099299 | 99.2% | 163.01 g/mol | C5H7BrO | 5 G
Propargyl-PEG1-bromide is a small polyethylene glycol (PEG) derivative bearing a terminal propargyl (alkyne) group and a bromide leaving group. It is designed for use as a reactive linker or alkylating reagent in bioconjugation, click chemistry, and drug-delivery research. Supplied as a liquid, it provides a short PEG spacer with an alkyne handle for efficient coupling reactions.
- Provides terminal alkyne for copper-catalyzed azide-alkyne cycloaddition.
- Contains a bromide leaving group for nucleophilic substitution reactions.
- Short PEG spacer improves aqueous solubility and reduces steric hindrance.
- Suitable for conjugation and linker synthesis in medicinal chemistry workflows.
- Compatible with standard storage recommendations when handled under inert atmosphere.
Medchemexpress LLC Tert-butyl N-(5-hydroxypentyl)carbamate | 75178-90-4 | MFCD01862955 | >97.0% | 203.28 g·mol⁻1 | C10H21NO3 | 1 G
5-(Boc-amino)-1-pentanol is a Boc-protected 5-aminopentanol used as a versatile intermediate and linker in organic and medicinal chemistry. It contains a tert-butoxycarbonyl protected amine and a primary alcohol, enabling selective deprotection and further functionalization for synthesis of peptides, small molecules, and conjugates.
- Boc-protected amine enables selective deprotection workflows.
- Primary alcohol allows further derivatization and coupling reactions.
- High purity suitable for synthetic and medicinal chemistry applications.
- Defined storage stability in solvent and bulk formats.
- Useful as a linker for conjugation and building-block synthesis.
eMolecules Propargyl-PEG9-bromide | 2055042-83-4 | MFCD29079385 | 500mg
Broadpharm | Propargyl-PEG9-bromide | 500mg | 298819246 | BP-23120 | 98.000 | 2055042-83-4 | MFCD29079385 | 515.438 | C21H39BrO9
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eMolecules Propargyl-PEG10-amine | 2112737-25-2 | MFCD30730361 | 1g
Broadpharm | Propargyl-PEG10-amine | 1g | 347153785 | BP-23637 | 98.000 | 2112737-25-2 | MFCD30730361 | 495.610 | C23H45NO10
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Medchemexpress LLC Propargyl-peg8-oh | 1351556-81-4 | 250 MG
Propargyl-PEG8-OH is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, allowing it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules that contain Azide groups.
- Utilized in the synthesis of protacs
- Functions as a click chemistry reagent
- Contains an alkyne group for CuAAC reactions
- Leverages the intracellular ubiquitin-proteasome system
Medchemexpress LLC Propargyl-PEG6-acid | 1951438-84-8 | 348.39 g·mol⁻1 | C16H28O8 | 100 MG
Propargyl-PEG6-acid is a PEG-based linker bearing a terminal propargyl (alkyne) group, used as a click-chemistry reagent and as a linker in the synthesis of PROTACs and antibody-drug conjugates. The PEG6 spacer increases hydrophilicity and enables conjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Contains a terminal propargyl (alkyne) functional group.
- Suitable for copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Used in synthesis of PROTACs and antibody-drug conjugates.
- PEG6 spacer provides hydrophilicity and improved solubility.
- Storage recommendations: pure form refrigerated or frozen for long-term stability; store solutions frozen.
Medchemexpress LLC (2,5-dioxopyrrolidin-1-yl) hex-5-ynoate | 906564-59-8 | MFCD28898858 | 97.0% | 209.20 g/mol | C10H11NO4 | 50 MG
Propargyl-C2-NHS ester is an alkyne-containing N-hydroxysuccinimide (NHS) ester used for bioconjugation. It serves as a non-cleavable linker and a click-chemistry reagent enabling copper-catalyzed azide-alkyne cycloaddition (CuAAC) with azide-bearing molecules.
- Contains a propargyl (alkyne) group for CuAAC reactions.
- Designed for antibody conjugation and general bioconjugation.
- Molecular formula C10H11NO4; molecular weight 209.20 g/mol.
- High purity: 97.0%.
- Stored at -20°C in pure form; available in small pack sizes for research use.
Medchemexpress LLC E -Pent-2-enal 50g
(E)-Pent-2-enal has a pungent fruity odor This compound is commonly used in the flavor and fragrance industry because of its strong aroma often described as fresh and green Furthermore (E)-Pent-2-enal can be used as an intermediate in the synthesis of various organic compounds including pharmaceuticals and agrochemicals Its unique chemical properties make it an important ingredient in many commercial products including perfumes air fresheners and cleaners
Medchemexpress LLC Propargyl-PEG3-amine | 932741-19-0 | ≥98.0% | 187.24 | 50 MG
Propargyl-PEG3-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, possessing an alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups. PROTACs use the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains an alkyne group for CuAAc reactions with azide groups
![Medchemexpress LLC 2-[2-(2-propynyloxy)ethoxy]ethanamine | 944561-44-8 | MFCD19160595 | 98.9% | 143.18 g/mol | C7H13NO2 | 25 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202930.png-250.jpg)
Medchemexpress LLC 2-[2-(2-propynyloxy)ethoxy]ethanamine | 944561-44-8 | MFCD19160595 | 98.9% | 143.18 g/mol | C7H13NO2 | 25 G
Propargyl-PEG2-amine is a propargyl-terminated polyethylene glycol (PEG2) amine linker used for bioconjugation and synthetic chemistry. It is commonly used as a non-cleavable ADC linker, as a PEG-based PROTAC linker, and as a terminal alkyne reagent for copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- Non-cleavable ADC linker for antibody-drug conjugate synthesis.
- Suitable as a PEG-based PROTAC linker.
- Terminal alkyne enables CuAAC click reactions with azides.
- Primary amine allows amide coupling and NHS-ester chemistry.
- Molecular formula C7H13NO2 and molecular weight 143.18 g/mol.
- High reported purity (manufacturer batch example ~98.9%), batch-dependent.
- Available in multiple pack sizes, including 25 G and larger quantities.
Medchemexpress LLC 3-Butynyl p-toluenesulfonate | 23418-85-1 | MFCD00041687 | >97.0% | 224.28 g/mol | C11H12O3S | 5 G
Propargyl-tos (3-butynyl p-toluenesulfonate) is a propargyl-containing tosylate ester used as a cleavable linker and an alkynyl reagent for click chemistry, bioconjugation, and linker synthesis in medicinal chemistry. It is supplied as a purified solid for synthetic chemistry applications.
- Cleavable ADC linker and click chemistry reagent.
- Used in bioconjugation and linker synthesis.
- High purity (>97.0%) available for synthetic applications.
- Molecular weight 224.28 g/mol and formula C11H12O3S.
- Supplied in small pack sizes suitable for laboratory synthesis.
Medchemexpress LLC N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) | 2112732-01-9 | 519.58 | 100 MG
N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Alkyne group capable of copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. PROTACs themselves contain two distinct ligands linked together, one targeting an E3 ubiquitin ligase and the other the protein of interest, utilizing the intracellular ubiquitin-proteasome system for selective target protein degradation. This product is for research use only.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Click chemistry reagent
- Contains an alkyne group
- Capable of copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Reacts with azide-containing molecules
- Exploits ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Propargyl-PEG10-acid | 2055022-18-7 | 98.0% | 524.60 | 500 MG
Propargyl-PEG10-acid is a PEG derivative that features a propargyl group along with a terminal carboxylic acid. It functions as a click chemistry reagent, containing an Alkyne group, and is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules that possess Azide groups.
- PEG derivative
- Features a propargyl group
- Contains a terminal carboxylic acid
- Functions as a click chemistry reagent
- Contains an alkyne group
- Capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Suitable for PROTAC synthesis
- Used as a biochemical assay reagent