Acetylides
Medchemexpress LLC Propargyl-peg8-nh2 | 1196732-52-1 | ≥98.0% | 407.50 | C19H37NO8 | 25 MG
Propargyl-PEG8-NH2 is a polyethylene glycol (PEG) based bifunctional linker bearing a terminal propargyl (alkyne) group and a primary amine. It is used for bioconjugation and as a non-cleavable linker in ADC and PROTAC synthesis, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAC) and amine-based coupling reactions.
- Contains terminal alkyne (propargyl) and primary amine functional groups.
- PEG8 spacer provides flexibility and solubility for conjugates.
- Suitable for CuAAC click chemistry with azide-containing partners.
- High purity (≥98.0%) for research and conjugation workflows.
- Molecular weight approximately 407.50 Da and formula C19H37NO8.
- Available in multiple package sizes to suit synthesis scale.
(C)C#C | 500g | 388714762](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000483075.jpg-250.jpg)
eMolecules 1066-54-2 | Trimethylsilylacetylene | Combi-Blocks | MFCD00008569 | 98.220 | C5H10Si | 95.000 | C[Si](C)(C)C#C | 500g | 388714762
Trimethylsilylacetylene | Combi-Blocks | 1066-54-2 | MFCD00008569 | 98.220 | C5H10Si | 95.000 | C[Si](C)(C)C#C | 500g | 388714762
Medchemexpress LLC Bis-propargyl-PEG8 25mg | 1092554-87-4 | 446.53 | C22H38O9 | 25 MG
Bis-propargyl-PEG8 is a PEG-based bifunctional linker bearing terminal propargyl (alkyne) groups. It is used in click chemistry (copper-catalyzed azide-alkyne cycloaddition) and for assembling PROTACs and other bioconjugates in research settings.
- Contains terminal alkyne groups suitable for CuAAC reactions.
- PEG8 spacer provides water solubility and flexible linkage.
- Bifunctional ends enable conjugation to two partners.
- Available in research-scale package sizes for synthesis workflows.
- Compatible with common organic synthesis and bioconjugation methods.
eMolecules 32199-97-6 | Propargyl-PEG14-alcohol | Broadpharm | MFCD28976685 | 628.753 | C29H56O14 | 98.000 | OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C | 1g | 550804246
Propargyl-PEG14-alcohol | Broadpharm | 32199-97-6 | MFCD28976685 | 628.753 | C29H56O14 | 98.000 | OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C | 1g | 550804246
Medchemexpress LLC Propargyl-PEG9-amine | 2093153-98-9 | 97.0% | 1 G
Propargyl-PEG9-amine is a PEG-based PROTAC linker. It is used in the synthesis of PROTACs and functions as a click chemistry reagent, containing an Alkyne group. It can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules that contain Azide groups. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Functions as a click chemistry reagent
- Contains an alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
- Peg-based PROTAC linker
- Used in the synthesis of PROTACs
- Supports selective degradation of target proteins
Medchemexpress LLC VH032-PEG3-acetylene | 2098799-80-3 | 98.1% | 25 MG
VH032-PEG3-acetylene is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. This compound is also a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Synthesized E3 ligase ligand-linker conjugate
- Incorporates a VH032 based VHL ligand
- Utilizes a linker employed in PROTAC technology
- Functions as a click chemistry reagent
- Contains an alkyne group
- Capable of copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
Medchemexpress LLC Bis-PEG1-C-PEG1-CH2COOH | 2358775-67-2 | 95.0% | 10 MG
Bis-PEG1-C-PEG1-CH2COOH (PROTAC Linker 26) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Peg-based protac linker
- Used in the synthesis of protacs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC 3,6,9,12,15,18,21-Heptaoxatetracos-23-yn-1-ol | 1422023-54-8 | ≥97.0% | 250 MG
Propargyl-PEG7-alcohol is a chemical compound identified by CAS number 1422023-54-8. It has a molecular formula of C17H32O8 and a molecular weight of 364.43. This compound is typically found as a colorless to light yellow liquid, with a purity of ≥97.0%. It is intended for research use only.
- Molecular formula: C17H32O8
- Molecular weight: 364.43
- Purity: ≥97.0%
- Appearance: colorless to light yellow liquid
- Storage for pure form: 3 years at -20°C, 2 years at 4°C
- Storage in solvent: 6 months at -80°C, 1 month at -20°C