Lignans and related compounds
Selleck Chemical LLC O-Demethyl-Gefitinib-E0833-5MG
O-Desmethyl gefitinib a major active metabolite of gefitinib is a potent EGFR (ErbB1/HER1) inhibitor inhibits subcellular EGFR tyrosine kinase through a mechanism similar to that of gefitinib with IC50 values of 36 and 22 nM respectively
Apexbio Technology LLC Etoposide 33419-42-0 10mM (in 1mL DMSO)
Etoposide (VP-16) is a topoisomerase II inhibitor widely used in biomedical research to study mechanisms of DNA damage and cancer therapy It forms a stabilized complex with DNA and topoisomerase II preventing the enzyme-mediated religation of cleaved DNA strands Resulting DNA double-strand breaks lead to apoptosis particularly in rapidly dividing cancer cells Reported IC50 values vary across cell lines such as 59 2 M for topoisomerase II inhibition 30 16 M in HepG2 and 0 051 M for MOLT-3 indicating differential cytotoxic responses to etoposide in various cancer cell models
Medchemexpress LLC N-demethyl lincomycin hydrochloride | 14600-41-0 | >95.0% | 428.97 g/mol | C17H33ClN2O6S | 2.5 MG
N-demethyl lincomycin hydrochloride is the hydrochloride salt of 4'-propyl-N-demethyllincomycin and is described as an impurity of lincomycin. It is provided for research and analytical use as an impurity/reference standard and is not for human consumption.
- Hydrochloride salt form suitable for analytical use.
- Used as an impurity standard for lincomycin impurity profiling.
- CAS number 14600-41-0 and molecular formula C17H33ClN2O6S.
- Molecular weight approximately 428.97 g/mol.
- Typical purity >95.0% (HPLC) for reference use.
- Provided in small laboratory quantities for analytical workflows.
Medchemexpress LLC 5-O-Demethyl-28-hydroxy-Avermectin A1a | 96722-46-2 | 96.0% | 889.08 | 1 MG
5-O-Demethyl-28-hydroxy-Avermectin A1a is a degradation product of Avermectin B1a. It is intended for research use only.
- Degradation product of Avermectin B1a
- For research use only
- Purity: 96.0%
- Molecular weight: 889.08
- Appearance: White to off-white solid
- Storage for powder: -20°C for 3 years, 4°C for 2 years
- Storage in solvent: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC Etoposide impurity 1 (standard) | 23363-35-1 | 562.52 | 50 MG
Etoposide impurity 1, also known as Lignan P, is an analytical and reference standard intended strictly for research and analytical applications. It is not for patient use and is commonly employed in qualitative, quantitative, and methodological research experiments.
- Useful in techniques such as High-Performance Liquid Chromatography (HPLC), Gas Chromatography (GC), and Mass Spectrometry (MS).
- Molecular weight: 562.52
- Molecular formula: C27H30O13
Medchemexpress LLC Etoposide | 33419-42-0 | 588.56 | 1 ML
Etoposide (VP-16; VP-16-213) is an anti-cancer chemotherapy agent that inhibits topoisomerase II, thereby stopping DNA replication and inducing cell cycle arrest, apoptosis, and autophagy.
- Acts as an anti-cancer chemotherapy agent
- Inhibits topoisomerase II activity
- Stops DNA replication
- Induces cell cycle arrest, apoptosis, and autophagy
- Soluble in DMSO for in vitro studies
- Applicable for cancer and infection research
Pfanstiehl Inc Podophyllotoxin (P-126) 100g pack API, active pharmaceutical ingredient CAS: 518-28-5
Podophyllotoxin (P-126) 100g pack API, active pharmaceutical ingredient CAS: 518-28-5
AdipoGen Podophyllotoxin
Chemical. CAS 518-28-5. Formula C22H22O8. MW 414.4. Isolated from Podophyllum emodi rhizomes. Potent microtubule assembly inhibitor. Anticancer compound. Cell death inducer. DNA topoisomerase II inhibitor. Cell cycle inhibitor at the metaphase. Antiviral and antihelminthic.
Apexbio Technology LLC Etoposide, 33419-42-0, MFCD00869325, 100 mg
MF: C29H32O13, MW: 588.56, Solubility: 29.45mg/mL in DMSO. Etoposide (VP-16) is the first agent recognized as a topoisomerase II inhibitor of anticancer drug with IC50 of 59.2 uM.
Medchemexpress LLC Rac N-demethyl promethazine hydrochloride | 60113-77-1 | MFCD18379322 | 25mg
N-demethyl Promethazine hydrochloride is a metabolite of Phenothiazine (HY-Y0055) Phenothiazine is an antibiotic which has insecticidal fungicidal antibacterial and anthelmintic activities
Medchemexpress LLC D-Glucurono-6,3-lactone acetonide | 20513-98-8 | >98% | 216.19 | 50 G
D-Glucurono-6,3-lactone acetonide can be converted to optically active and partially protected inositols. This product is for research use only and not intended for patient use.
- For research use only
- Can be converted to optically active and partially protected inositols
Medchemexpress LLC D-Glucurono-6,3-lactone acetonide | 20513-98-8 | 216.19 | 100 G
D-Glucurono-6,3-lactone acetonide can be converted to optically active and partially protected inositols.
- For research use only.
