Lignans and related compounds
Sigma Aldrich Fine Chemicals Biosciences SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES
NC3909202 N-DEMETHYL ONDANSETRON 100MG
Medchemexpress LLC Anthracene-9-carboxylic acid | 723-62-6 | MFCD00001257 | 222.24 g/mol | C15H10O2 | 1 ML
Anthracene-9-carboxylic acid is an anthracene derivative supplied as a 10 mM solution in DMSO and as solid material. It is used in electrophysiology and cellular studies to block and identify Ca2+-activated Cl- currents (CaCCs). Chemical identifiers: CAS 723-62-6; formula C15H10O2; molecular weight 222.24 g/mol.
- Supplied as a ready-to-use 10 mM solution in DMSO.
- Available as solid for synthesis and analytical use.
- Acts as a blocker and identifier of Ca2+-activated Cl- currents in cell studies.
- Well-characterized chemical properties for reproducible experimental use.
TARGETMOL CHEMICALS INC Etoposide 500MG
Also available in 1 mL, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Etoposide (VP-16-213) is a topoisomerase II inhibitor that inhibits DNA synthesis by forming a complex with topoisomerase II and DNA (IC50=60.3 uM). Etoposide has antitumor activity and induces apoptosis and autophagy. Purity 99.95%
Medchemexpress LLC N-demethyl lincomycin hydrochloride | 14600-41-0 | MFCD00008831 | >95.0% | 428.97 | C17H33ClN2O6S | 1 MG
N-demethyl lincomycin hydrochloride is the N-demethylated derivative of lincomycin supplied as the hydrochloride salt for research and analytical applications. It is provided as an impurity reference for impurity profiling and method development in analytical laboratories.
- Hydrochloride salt form for improved handling and solubility.
- Intended for use as an analytical standard and impurity reference.
- Applicable to HPLC and method development workflows.
- Molecular formula C17H33ClN2O6S and molecular weight 428.97 g/mol.
- Available in small-scale quantities suitable for analytical testing.
Selleck Chemical LLC Teniposide-25mg
Teniposide (NSC 122819, VM-26) is a chemotherapeutic medication mainly used in the treatment of childhood acute lymphocytic leukemia (ALL).
Medchemexpress LLC O-demethyl lenvatinib hydrochloride | 97.1% | 449.29 g/mol | C20H18Cl2N4O4 | 5 MG
O-demethyl lenvatinib hydrochloride is the O-demethylated metabolite of the kinase inhibitor lenvatinib, provided as a hydrochloride salt for research and analytical applications. It is intended as an analytical standard for in vitro studies, method development, and metabolite identification.
- Metabolite of lenvatinib for metabolite profiling and analytical reference.
- Hydrochloride salt form for improved stability and handling.
- High purity (97.1%) suitable for analytical workflows.
- Small 5 mg pack size ideal for method development and reference use.
- Molecular weight 449.29 g/mol and formula C20H18Cl2N4O4 for accurate calculations.
Medchemexpress LLC N-desmethyl promethazine hydrochloride | 60113-77-1 | MFCD18379322 | 5mg
N-demethyl Promethazine hydrochloride is a metabolite of Phenothiazine (HY-Y0055) Phenothiazine is an antibiotic which has insecticidal fungicidal antibacterial and anthelmintic activities
Apexbio Technology LLC Podophyllotoxin 518-28-5 10mM (in 1mL DMSO)
Podophyllotoxin (CAS 518-28-5) is a naturally occurring lignan that acts as a microtubule assembly inhibitor by binding to tubulin thereby disrupting mitotic spindle formation and inhibiting cell division This mechanism underlies its antineoplastic activity making it a valuable tool in studies of cell cycle regulation cytoskeletal dynamics and anticancer drug development Podophyllotoxin is widely used in biomedical research to investigate mechanisms of cytotoxicity and to screen for compounds targeting mitotic pathways The compound is supplied as 100 mg in a glass bottle or 50 mg in a poly bottle
Medchemexpress LLC Etoposide | 33419-42-0 | C29H32O13 | 10MG
Etoposide (Standard) is an analytical reference standard of the antineoplastic agent etoposide (CAS 33419-42-0). It is intended for research and analytical applications such as assay development, method validation, and quality control. The material has confirmed purity of 99.62% by HPLC and is supplied with supporting documentation for traceability.
- High purity reference material, 99.62% by HPLC.
- Intended for assay development and method validation.
- Suitable for quality control and analytical testing.
- Applicable to studies of topoisomerase II inhibition and related pharmacology.
- Provided with a certificate of analysis to support traceability.
Selleck Chemical LLC Demethyl-Coclaurine S3294-5mg
Demethyl-Coclaurine (Higenamine Norcoclaurine) the key component of the Chinese herb aconite root is a beta-2 adrenergic receptor ( 2-AR) agonist Demethyl-Coclaurine stimulates AKT phosphorylation and requires PI3K activation for the anti-apoptotic effect in cardiomyocytes
Medchemexpress LLC Etoposide impurity 1 | 23363-35-1 | MFCD01725594 | 562.52 g/mol | C27H30O13 | 5 MG
Etoposide impurity 1 is an analytical impurity standard of the chemotherapeutic agent etoposide, supplied for method development, impurity profiling, and quality control. It is provided as a solid material with defined storage recommendations to maintain stability for analytical use.
- Analytical reference standard for impurity profiling and method development.
- White to off-white solid suitable for HPLC and LC-MS analyses.
- Molecular formula C27H30O13; molecular weight 562.52 g/mol.
- Available in small pack sizes, including 5 MG, for trace-level studies.
- Store at 4°C under inert gas; in solvent: -80°C (6 months) or -20°C (1 month).
Abcam Picropodophylloto x in, IGF-1R inhibitor, 25MG
MW 414.4 Da, Purity >97%. Selective insulin-like growth factor-1 receptor (IGF-1R) inhibitor. Reduces pAkt and pErk1/2. Does not compete with ATP and may inhibit IGF-1R autophosphorylation. Anticancer agent. Active in vitro and in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Selleck Chemical LLC Etoposide S1225-10g
Etoposide is a semisynthetic derivative of podophyllotoxin which inhibits DNA synthesis via topoisomerase II inhibition activity which enhances double-strand and single-strand cleavage of DNA and reversibly inhibits repair by topoisomerase II binding Etoposide induces autophagy mitophagy and apoptosis
AdipoGen Podophyllotoxin
Chemical. CAS 518-28-5. Formula C22H22O8. MW 414.4. Isolated from Podophyllum emodi rhizomes. Potent microtubule assembly inhibitor. Anticancer compound. Cell death inducer. DNA topoisomerase II inhibitor. Cell cycle inhibitor at the metaphase. Antiviral and antihelminthic.