Hydrobromides
Selleck Chemical LLC Arecoline HBr S2614-50mg
Arecoline(NSC-31750) is a muscarinic acetylcholine receptor agonist
Medchemexpress LLC CPTH6 hydrobromide 1mg | 2321332-57-2 | 1 MG
CPTH6 hydrobromide is a thiazole-derived small molecule that modulates histone acetyltransferase activity and induces apoptotic and autophagic features in leukemia cell lines. It is provided as the hydrobromide salt for use in biochemical and cell-based cancer research applications.
- Thiazole-derived HAT inhibitor that reduces histone acetylation.
- Promotes apoptotic program and increases autophagic features in leukemia cells.
- Provided as a solid hydrobromide salt for improved handling and stability.
- Suitable for biochemical assays and cell-based studies of acetylation-dependent processes.
- Supplied in small research quantities for screening and mechanistic experiments.
Medchemexpress LLC Arecoline | 63-75-2 | 100 MG
Arecoline is a naturally brain-penetrant and orally active psychoactive alkaloid. It functions as a partial agonist of nicotinic and muscarinic acetylcholine receptors. It has been observed to exhibit stimulation, alertness, anxiolysis, and anti-parasitic effects. Research indicates it can also induce oxidative stress.
- Partial agonist of nicotinic and muscarinic acetylcholine receptors
- Exhibits stimulation and alertness
- Demonstrates anxiolysis and anti-parasitic effects
- Induces generation of reactive oxygen species
- Causes cell cycle arrest at G1/G0 phase in HaCaT cells
- Upregulates hemeoxygenase-1, ferritin light chain, glucose-6-phosphate dehydrogenase, glutamate-cysteine ligase catalytic subunit, and glutathione reductase expression
- Alleviates anxiety and depression in CFA-induced mice
Medchemexpress LLC Eletriptan hydrobromide | 177834-92-3 | 99.8% | C22H27BrN2O2S | 100 MG
Eletriptan hydrobromide is a 5-HT1B and 5-HT1D receptor agonist with antimigraine activity, exhibiting Ki values of 0.92 nM and 3.14 nM, respectively. It is intended for research use only. In vivo studies have shown that eletriptan hydrobromide dose-dependently reduces carotid blood flow in anesthetized dogs and inhibits dural plasma protein extravasation in anesthetized rats.
- Functions as a 5-HT1B and 5-HT1D receptor agonist.
- Exhibits Ki values of 0.92 nM for 5-HT1B receptor.
- Exhibits Ki values of 3.14 nM for 5-HT1D receptor.
- Dose-dependently reduces carotid blood flow in anesthetized dogs.
- Inhibits dural plasma protein extravasation in anesthetized rats.
- Completely inhibits plasma protein extravasation from the dura mater at 100 μg/kg.
Apexbio Technology LLC SR 95531 hydrobromide 104104-50-9 50mg
SR 95531 hydrobromide (CAS 104104-50-9) also known as Gabazine is a selective competitive antagonist of the GABAA receptor By binding to the GABA recognition site on the receptor it blocks the activation induced by -aminobutyric acid (GABA) Experimental studies report an inhibitory concentration (IC50) of approximately 0 2 M for GABAA receptor-mediated responses Widely utilized in neuroscience research Gabazine is applied to investigate the physiological and pathological roles of GABAA receptor-mediated synaptic transmission neural network modulation and neurotransmitter regulation
Medchemexpress LLC Darifenacin hydrobromide | 133099-07-7 | 99.78% | C28H31BrN2O2 | 100 MG
Darifenacin hydrobromide (UK-88525) is a selective and orally active antagonist of the M3 muscarinic receptor (M3R) with a pKi of 8.9. It exhibits over 20-fold greater specificity for M3R compared to other muscarinic receptors. This compound is utilized in research for studying urinary incontinence and other symptoms associated with overactive bladder. Additionally, Darifenacin hydrobromide has demonstrated inhibitory effects on tumor growth in colorectal cancer cells and possesses anti-tumor properties.
- Selective M3 muscarinic receptor antagonist
- Over 20-fold greater specificity for M3R
- Used in research for urinary incontinence and overactive bladder symptoms
- Demonstrates inhibitory effects on tumor growth in colorectal cancer cells
- Possesses anti-tumor properties
Medchemexpress LLC Guvacoline hydrobrom 25mg | 17210-51-4 | 25 MG
Guvacoline hydrobromide is the hydrobromide salt of guvacoline, a pyridine alkaloid found in Areca triandra. It is used as a research reagent and functions as a weak full agonist of atrial and ileal muscarinic acetylcholine receptors (mAChR).
- Acts as a weak full agonist of atrial and ileal muscarinic receptors.
- White to off-white solid physical form.
- Molecular formula C7H12BrNO2 and molecular weight 222.08.
- Purity typically around 96.09% by HPLC.
- Store sealed at 4°C and protect from moisture and light; in solution store at -80°C for long-term.
- Supplied in small milligram pack sizes for laboratory research.
Medchemexpress LLC Galanthamine hydrobromide (Galantamine hydrobromide) | 1953-04-4 | 99.9% | C17H22BrNO3 | 500 MG
Galanthamine hydrobromide is a selective, reversible, competitive, alkaloid AChE inhibitor with an IC50 of 0.35 μM. It also acts as a potent allosteric potentiating ligand (APL) for human α3β4, α4β2, and α6β4 nicotinic receptors (nAChRs). This compound is primarily developed for research into Alzheimer's disease (AD).
- Selective, reversible, competitive alkaloid AChE inhibitor
- Potent allosteric potentiating ligand of human α3β4, α4β2, α6β4 nicotinic receptors (nAChRs)
- Developed for Alzheimer's disease (AD) research
- IC50 of 0.35 μM for AChE
Apexbio Technology LLC Homatropine Bromide 51-56-9 5g
Homatropine Bromide (CAS 51-56-9) is a small molecule antagonist of muscarinic acetylcholine receptors (AChRs) It selectively inhibits muscarinic receptor-mediated responses in endothelial and smooth muscle cells with reported IC50 values of 162 5 nM and 170 3 nM for WKY-E and SHR-E cell models respectively This compound serves as a valuable tool for investigating the role of muscarinic signaling in vascular function and smooth muscle physiology within experimental research settings