Hydrobromides
Medchemexpress LLC Adtn hydrobromide | 13575-86-5 | 98.0% | 10 MG
ADTN hydrobromide is the hydrobromide salt of ADTN, a long-acting dopamine receptor agonist used in research to probe dopaminergic signaling. It is supplied as a small, high-purity reagent for laboratory studies and has been reported to reduce behavioral visual threshold in DA-IPC-depleted zebrafish.
- Long-acting dopamine receptor agonist.
- Used to study dopaminergic signaling and zebrafish visual behavior.
- High purity: 98.0%.
- Supplied in a small research pack suitable for small-scale assays.
- Molecular formula C10H14BrNO2, molecular weight 260.13 g/mol.
Accela Chembio Inc 3-(bromomethyl)pyridine Hydrobromide | 5g | 4916-55-6 | MFCD01321314 | 95+% | Shelf Life: 1260 Days | Light Sensitive/nitrogen Or Argon/+4
3-(bromomethyl)pyridine Hydrobromide | 5g | 4916-55-6 | MFCD01321314 | 95+% | Shelf Life: 1260 Days | Light Sensitive/nitrogen Or Argon/+4
Apexbio Technology LLC Scopolamine hydrobromide 114-49-8 500mg
Scopolamine hydrobromide (114-49-8) is a small-molecule antagonist targeting muscarinic acetylcholine receptors and serotonin 5-HT3 receptors It is designed to reversibly block these receptors thereby modulating cholinergic and serotonergic signaling pathways Scopolamine hydrobromide exerts its biological activity primarily through reversible antagonism of muscarinic receptors and inhibition of serotonin 5-HT3 receptor responses In receptor binding studies Scopolamine hydrobromide demonstrates antagonistic activity with reported IC50 values generally ranging from nanomolar to micromolar concentrations depending on the receptor subtype and experimental conditions Based on these pharmacological properties Scopolamine hydrobromide holds research potential in studies of neurotransmission cholinergic signaling gastrointestinal motility assays cognitive impairment models and emesis reflex investigations
Medchemexpress LLC Burixafor hydrobromide | 1191450-19-7 | 98.0% | 769.01 | 100 MG
Burixafor (TG-0054) hydrobromide is a potent CXCR4 antagonist with a pIC50 of 7.4. It inhibits the binding of CXCL12 to CXCR4, antagonizes CXCL12-induced recruitment of Gαᵢ and β-arrestin2, and blocks the downstream Gαᵢ-mediated inhibitory effect on cAMP signal transduction. Burixafor hydrobromide mobilizes CD34+ hematopoietic stem/progenitor cells (HSPC) from the bone marrow to the peripheral blood and can be used for research on autologous hematopoietic stem cell transplantation (ASCT).
- Potent CXCR4 antagonist with a pIC50 of 7.4
- Inhibits CXCL12 binding to CXCR4
- Antagonizes CXCL12-induced recruitment of Gαᵢ and β-arrestin2
- Blocks downstream Gαᵢ-mediated inhibitory effect on cAMP signal transduction
- Mobilizes CD34+ hematopoietic stem/progenitor cells (HSPC) from bone marrow to peripheral blood
- Can be used for research on autologous hematopoietic stem cell transplantation (ASCT)
Medchemexpress LLC Burixafor hydrobromide | 1191450-19-7 | 98.0% | 769.01 | 200 MG
Burixafor (TG-0054) hydrobromide is a potent CXCR4 antagonist with a pIC50 of 7.4. It inhibits the binding of CXCL12 to CXCR4, antagonizes CXCL12-induced recruitment of Gαᵢ and β-arrestin2, and blocks the downstream Gαᵢ-mediated inhibitory effect on cAMP signal transduction. It mobilizes CD34+ hematopoietic stem/progenitor cells (HSPC) from the bone marrow to the peripheral blood and can be used for research on autologous hematopoietic stem cell transplantation (ASCT).
- Potent CXCR4 antagonist (pIC50 of 7.4)
- Inhibits CXCL12 binding to CXCR4
- Antagonizes CXCL12-induced recruitment of Gαᵢ and β-arrestin2
- Blocks downstream Gαᵢ-mediated inhibitory effect on cAMP signal transduction
- Mobilizes CD34+ hematopoietic stem/progenitor cells (HSPC) from bone marrow to peripheral blood
- Potential for research on autologous hematopoietic stem cell transplantation (ASCT)
Medchemexpress LLC Burixafor hydrobromide | 1191450-19-7 | 98.0% | 769.01 | 500 MG
Burixafor (TG-0054) hydrobromide is a potent CXCR4 antagonist with a pIC50 of 7.4. It inhibits the binding of CXCL12 to CXCR4, antagonizes CXCL12-induced recruitment of Gαᵢ and β-arrestin2, and blocks the downstream Gαᵢ-mediated inhibitory effect on cAMP signal transduction. Burixafor hydrobromide mobilizes CD34+ hematopoietic stem/progenitor cells (HSPC) from the bone marrow to the peripheral blood.
- Can be used for research on autologous hematopoietic stem cell transplantation (ASCT).
- Potent CXCR4 antagonist.
- Inhibits CXCL12 binding to CXCR4.
- Blocks Gαᵢ-mediated inhibitory effect on cAMP signal transduction.
- Mobilizes CD34+ hematopoietic stem/progenitor cells.
Medchemexpress LLC Darifenacin hydrobromide | 133099-07-7 | 99.8% | C28H31BrN2O2 | 5 MG
Darifenacin hydrobromide is a selective and orally active M3 muscarinic receptor (M3R) antagonist. It is used in the study of urinary incontinence and other symptoms of overactive bladder, and has demonstrated anti-tumor effects by inhibiting tumor growth in colorectal cancer cells. In vitro, it inhibits Kv currents and the phosphorylation of p38, ERK1/2, and Akt. In vivo studies showed antitumor effects in xenograft mouse models and decreased afferent activity in rat bladders.
- Selective and orally active M3 muscarinic receptor antagonist
- Used in the study of urinary incontinence and overactive bladder symptoms
- Exhibits anti-tumor effects in colorectal cancer cells
- Inhibits Kv currents in coronary arterial smooth muscle cells
- Decreases afferent activity of bladder Aδ and C fibers in female rats
TARGETMOL CHEMICALS INC VORTIOXETINE HYDROBROMID 100MG
Also available in 10 mg 25 mg 50 mg 200 mg 500 mg 1000 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Vortioxetine hydrobromide (Lu AA21004 hydrobromide) is a serotonin (5-HT) modulator and stimulator (SMS) inhibits 5-HT1A/1B/3A/7 receptor and SERT (IC50 15/33/3.7/19/1.6 nM). purity: 99%
Apexbio Technology LLC Imetit dihydrobromide 32385-58-3 10mg
Imetit dihydrobromide (CAS 32385-58-3) is a potent high-affinity agonist of histamine H3 and H4 receptors demonstrating Ki values of 0 3 nM and 2 7 nM respectively Functionally it replicates histaminergic effects by inducing morphological changes in eosinophils with an EC50 of 25 nM Owing to its selective receptor activity Imetit dihydrobromide is widely employed in studies investigating allergic inflammatory processes including asthma as well as in research focused on central nervous system physiology and histamine-related pathways
Medchemexpress LLC Remodelin (hydrobromide) | 1622921-15-6 | 99.6% | 363.28 | 500 MG
Remodelin hydrobromide is an orally active and selective inhibitor of acetyltransferase NAT10. It inhibits NAT10 activity, slows DNA replication, and suppresses the growth of prostate cancer cells. It also inhibits the growth of prostate cancer and hepatocellular carcinoma in xenograft models. Additionally, it enhances the healthspan in a Hutchinson-Gilford Progeria Syndrome (HGPS) mouse model.
- Orally active and selective inhibitor of acetyltransferase NAT10.
- Inhibits NAT10 activity.
- Slows DNA replication.
- Suppresses growth of prostate cancer cells.
- Inhibits the growth of prostate cancer and hepatocellular carcinoma in xenograft model.
- Enhances healthspan in Hutchinson-Gilford Progeria Syndrome (HGPS) mouse model.
Medchemexpress LLC Remodelin (hydrobromide) | 1622921-15-6 | 99.6% | 363.28 | 25 MG
Remodelin hydrobromide is an orally active and selective inhibitor of acetyltransferase NAT10. It inhibits NAT10 activity, slows DNA replication, and suppresses the growth of prostate cancer cells. This compound has been shown to inhibit the growth of prostate cancer and hepatocellular carcinoma in xenograft models, and enhances healthspan in a Hutchinson-Gilford Progeria Syndrome (HGPS) mouse model.
- Orally active and selective NAT10 inhibitor
- Inhibits NAT10 activity and slows DNA replication
- Suppresses growth of prostate cancer cells
- Inhibits growth of prostate cancer and hepatocellular carcinoma in xenograft models
- Enhances healthspan in HGPS mouse model
Medchemexpress LLC Scopolamine hydrobromide trihydrate | 6533-68-2 | MFCD00150066 | 99.86% | 438.31 | 50 MG
Scopolamine hydrobromide trihydrate, also known as Hyoscine hydrobromide trihydrate, is a potent muscarinic antagonist capable of crossing the blood-brain barrier. It competitively antagonizes 5-HT3 receptors with an IC50 of 2.09 μM. This compound has been observed to induce cognitive and memory deficits in animals. It is currently being investigated for its potential applications in the prevention of postoperative nausea and vomiting, motion sickness, and nervous system diseases.
- High-affinity muscarinic antagonist.
- Able to cross the blood-brain barrier.
- Competitively antagonizes 5-HT3 receptors.
- Used in research for preventing postoperative nausea and vomiting.
- Used in research for motion sickness.
- Used in research for nervous system diseases.
Medchemexpress LLC Eletriptan hydrobromide | 177834-92-3 | 99.8% | C22H27BrN2O2S | 50 MG
Eletriptan hydrobromide (Eletriptan HBr) is a 5-HT1B and 5-HT1D receptor agonist with antimigraine activity, with Ki values of 0.92 nM and 3.14 nM, respectively. It is for research use only and not sold to patients.
- 5-HT1B and 5-HT1D receptor agonist
- Antimigraine activity
Apexbio Technology LLC BD 1047 dihydrobromide 138356-21-5 50mg
BD 1047 dihydrobromide (CAS 138356-21-5) is a selective antagonist of the sigma-1 ( 1) receptor exhibiting Ki values of 0 93 nM for 1 and 47 nM for sigma-2 ( 2) receptors Sigma receptors distinct from opioid receptors include 1 and 2 subtypes and are implicated in modulating dopaminergic neurotransmission and drug-related behaviors In preclinical models BD 1047 dihydrobromide attenuates haloperidol- and DTG-induced dystonia and reverses cocaine-induced behavioral responses without affecting responses to natural rewards Additionally it alleviates mechanical allodynia in neuropathic pain models and modulates spinal 1 receptor and NR1 subunit expression This compound is utilized to investigate 1 receptor function in neuropharmacology and pain research
Selleck Chemical LLC Fenoterol hydrobromide
Fenoterol hydrobromide (Phenoterol) is the the hydrobromide salt of fenoterol a 2 adrenoreceptor agonist with bronchodilator activity