Hydrobromides
Medchemexpress LLC CCT031374 hydrobromide | 1219184-91-4 | MFCD06737234 | 98.1% | 434.33 g·mol⁻¹ | C23H20BrN3O | 5 MG
CCT031374 hydrobromide is the hydrobromide salt of a small-molecule β-catenin/TCF signaling inhibitor supplied for research use only. It is provided as an off-white to light yellow solid with high chemical purity and is intended for pathway inhibition, cell signaling assays, and preclinical studies.
- β-catenin/TCF signaling inhibitor
- High purity (98.1%)
- Molecular weight 434.33 g·mol⁻¹
- Off-white to light yellow solid form
- Available in milligram-scale packages for research use
- Intended for in vitro and in vivo research applications
Medchemexpress LLC SCH-202676 (hydrobromide) | 265980-25-4 | 96.8% | 348.26 | 25 MG
SCH-202676 hydrobromide is an allosteric modulator of G protein-coupled receptors (GPCRs) and adenosine receptor (AR). It exhibits antiviral activity, inhibiting 3CLpro in a time-dependent manner with an IC50 value of 0.655 μM.
- Allosteric modulator of G protein-coupled receptors (GPCRs)
- Allosteric modulator of adenosine receptor (AR)
- Antiviral activity
- Inhibits 3CLpro in a time-dependent manner
Medchemexpress LLC Nan-190 hydrobromide | 115338-32-4 | 99.1% | 474.39 | 200 MG
NAN-190 hydrobromide is a serotonin receptor 5-HT antagonist that selectively targets the 5-HT1A receptor. This compound is intended for research use only. In vivo studies demonstrate its ability to reverse the catalepsy-improving effect of fluoxetine in 6-OHDA lesioned rats.
- Selective antagonist of 5-HT1A receptor
- Antagonist of 5-HT1 receptor
- Suitable for research applications
Active Motif Arecoline hydrobromide
Active Motif's Arecoline hydrobromide is an inhibitor of acetyl-CoA acetyltransferase 1 (ACAT1). Tyrosine 407 phosphorylation activates mitochondrial acetyl-CoA ACAT1 by stabilizing its tetramer. This is believed to be the mechanisms by which ACAT1 is "hijacked" and contributes to the Warburg effect in cancer. Arecoline is a covalent inhibitor of ACAT1 which binds to and disrupts only ACAT1 tetramers (IC50 = 11.1 uM). ACAT2 and DLAT are not inhibited. Treatment of xenograft nude mice with Arecoline resulted in a dose-dependent reduction in tumor mass. It is an agonist at muscarinic acetylcholine receptors M1-M5 (EC50 in the range of 7-410 nM), and may be involved in dementia.
Medchemexpress LLC CCT031374 hydrobromide | 1219184-91-4 | 98.08% | 434.33 | 25 MG
CCT031374 hydrobromide is a potent inhibitor of β-catenin/transcription factor (TCF) complex signaling. It inhibits TCF-dependent transcription of genes in the Wnt signaling pathway and demonstrates antitumor activity.
- Potent inhibitor of β-catenin/TCF complex signaling
- Inhibits TCF-dependent transcription of Wnt signaling pathway genes
- Demonstrates antitumor activity
- For research use only
TARGETMOL CHEMICALS INC CCT 031374 HYDROBROMIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CCT 031374 hydrobromide is a TCF/(beta)-catenin inhibitor with antitumor activities. purity: 98%
Medchemexpress LLC NAN-190 hydrobromide | 115338-32-4 | 99.1% | 474.39 | 1 ML
NAN-190 hydrobromide is a serotonin receptor 5-HT antagonist and a selective antagonist of 5-HT1A. It is intended for research use only and can reverse the catalepsy-improving effect of fluoxetine in 6-OHDA lesioned rats.
- Appearance: solid
- Color: light yellow to yellow
- Shipping: room temperature in continental US; may vary elsewhere
- Storage: 4°C, sealed storage, away from moisture. In solvent: -80°C for 6 months; -20°C for 1 month (sealed storage, away from moisture)
- For research use only
Medchemexpress LLC 3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-1-methyl-, methyl ester, hydrobromide | 300-08-3 | 99.95% | 1 G
Arecoline hydrobromide is a naturally occurring psychoactive alkaloid that is brain-penetrant and orally active. It acts as a partial agonist of nicotinic and muscarinic acetylcholine receptors. It exhibits stimulation, alertness, anxiolysis, and anti-parasitic effects, and can also induce oxidative stress. It is intended for research use only.
- Acts as a partial agonist of nicotinic and muscarinic acetylcholine receptors.
- Exhibits stimulation, alertness, anxiolysis, and anti-parasitic effects.
- Can induce oxidative stress.
- Induces reactive oxygen species generation and G1/G0 phase cell cycle arrest in HaCaT cells.
- Alleviates anxiety and depression in CFA-induced mice.
eMolecules 180695-79-8 | TERT-BUTYL4-BROMOPIPERIDINE-1-CARBOXYLATE | AstaTech | MFCD04115039 | 264.163 | C10H18BrNO2 | 97.000 | CC(C)(C)OC(=O)N1CCC(Br)CC1 | 25g | 112534061
TERT-BUTYL4-BROMOPIPERIDINE-1-CARBOXYLATE | AstaTech | 180695-79-8 | MFCD04115039 | 264.163 | C10H18BrNO2 | 97.000 | CC(C)(C)OC(=O)N1CCC(Br)CC1 | 25g | 112534061
Apexbio Technology LLC Homatropine Bromide 51-56-9 1g
Homatropine Bromide (CAS 51-56-9) is a small molecule antagonist of muscarinic acetylcholine receptors (AChRs) It selectively inhibits muscarinic receptor-mediated responses in endothelial and smooth muscle cells with reported IC50 values of 162 5 nM and 170 3 nM for WKY-E and SHR-E cell models respectively This compound serves as a valuable tool for investigating the role of muscarinic signaling in vascular function and smooth muscle physiology within experimental research settings
Medchemexpress LLC Remodelin hydrobromide | 1622921-15-6 | 99.6% | 363.28 | 100 MG
Remodelin hydrobromide is an orally active and selective inhibitor of acetyltransferase NAT10. It inhibits NAT10 activity, slows DNA replication, and suppresses the growth of prostate cancer cells. It has been shown to inhibit the growth of prostate cancer and hepatocellular carcinoma in xenograft models. Additionally, Remodelin hydrobromide enhances the healthspan in the Hutchinson-Gilford progeria syndrome (HGPS) mouse model.
- Inhibits NAT10 activity and cell proliferation in prostate cancer cells.
- Slows DNA replication.
- Suppresses the growth of prostate cancer cells.
- Inhibits the growth of hepatocellular carcinoma in xenograft models.
- Enhances healthspan in the HGPS mouse model.
- Decreases nuclear shape defects and increases genomic stability in fibroblasts.