Hydrobromides
Medchemexpress LLC CCT031374 hydrobromide | 1219184-91-4 | MFCD06737234 | 98.1% | 434.33 g·mol⁻¹ | C23H20BrN3O | 5 MG
CCT031374 hydrobromide is the hydrobromide salt of a small-molecule β-catenin/TCF signaling inhibitor supplied for research use only. It is provided as an off-white to light yellow solid with high chemical purity and is intended for pathway inhibition, cell signaling assays, and preclinical studies.
- β-catenin/TCF signaling inhibitor
- High purity (98.1%)
- Molecular weight 434.33 g·mol⁻¹
- Off-white to light yellow solid form
- Available in milligram-scale packages for research use
- Intended for in vitro and in vivo research applications
Medchemexpress LLC Dihydro-β-erythroidine hydrobromide | 29734-68-7 | >98.0% | 356.25 g·mol⁻¹ | C16H22BrNO3 | 5 MG
Dihydro-β-erythroidine hydrobromide is a research reagent that acts as a competitive antagonist of neuronal nicotinic acetylcholine receptors, with preferential activity at α4β2 and α4β4 subtypes. Supplied as the hydrobromide salt, it is used in electrophysiology, receptor pharmacology, and in vivo studies to selectively inhibit nAChR-mediated responses.
- High purity (≥98% by HPLC).
- Selective antagonist for α4β2 and α4β4 nicotinic receptors.
- Suitable for in vitro and in vivo pharmacology studies.
- Supplied as hydrobromide salt for improved stability and solubility.
- Available in small research package sizes (1 mg, 5 mg, 10 mg).
- Documented identifiers include CAS 29734-68-7 and molecular weight 356.25 g·mol⁻¹.
Medchemexpress LLC NAN-190 hydrobromide | 115338-32-4 | 99.1% | 474.39 | 100 MG
NAN-190 hydrobromide is a serotonin receptor 5-HT antagonist and a selective antagonist of 5-HT1A. It is intended for research use only.
- Appearance: Solid
- Color: Light yellow to yellow
- Shipping: Room temperature in continental US; may vary elsewhere
- Storage: 4°C, sealed storage, away from moisture. In solvent: -80°C, 6 months; -20°C, 1 month
Medchemexpress LLC 3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-1-methyl-, methyl ester, hydrobromide | 300-08-3 | 99.95% | 1 G
Arecoline hydrobromide is a naturally occurring psychoactive alkaloid that is brain-penetrant and orally active. It acts as a partial agonist of nicotinic and muscarinic acetylcholine receptors. It exhibits stimulation, alertness, anxiolysis, and anti-parasitic effects, and can also induce oxidative stress. It is intended for research use only.
- Acts as a partial agonist of nicotinic and muscarinic acetylcholine receptors.
- Exhibits stimulation, alertness, anxiolysis, and anti-parasitic effects.
- Can induce oxidative stress.
- Induces reactive oxygen species generation and G1/G0 phase cell cycle arrest in HaCaT cells.
- Alleviates anxiety and depression in CFA-induced mice.
Medchemexpress LLC NAN-190 hydrobromide | 115338-32-4 | 99.1% | 474.39 | 1 ML
NAN-190 hydrobromide is a serotonin receptor 5-HT antagonist and a selective antagonist of 5-HT1A. It is intended for research use only and can reverse the catalepsy-improving effect of fluoxetine in 6-OHDA lesioned rats.
- Appearance: solid
- Color: light yellow to yellow
- Shipping: room temperature in continental US; may vary elsewhere
- Storage: 4°C, sealed storage, away from moisture. In solvent: -80°C for 6 months; -20°C for 1 month (sealed storage, away from moisture)
- For research use only
Medchemexpress LLC Arecoline hydrobromide | 300-08-3 | 99.9% | 100 MG
Arecoline hydrobromide is a naturally brain-penetrant and orally active psychoactive alkaloid. It functions as a partial agonist of nicotinic and muscarinic acetylcholine receptors, exhibiting stimulation, alertness, anxiolysis, and anti-parasitic effects. It can also induce oxidative stress.
- Acts as a partial agonist of nicotinic and muscarinic acetylcholine receptors
- Exhibits stimulation, alertness, anxiolysis, and anti-parasitic effects
- Induces generation of reactive oxygen species and cell cycle arrest in HaCaT cells
- Up-regulates stress-responsive genes
- Alleviates anxiety and depression in CFA-induced mice
Apexbio Technology LLC 6-Hydroxydopamine hydrobromide(Synonyms: Oxidopamine hydrobromide, 6-OHDA hydrobromide, 6-Hydroxydopamine HBr), 50mg, CAS: 636-00-0.
6-Hydroxydopamine hydrobromide (CAS 636-00-0) commonly referred to as 6-OHDA hydrobromide is a catecholamine-derived neurotoxin frequently used in neuroscience research to induce selective dopaminergic neuronal degeneration Upon administration it generates intracellular reactive oxygen species (ROS) activating apoptotic pathways via caspase-3 -8 and -9 as demonstrated in PC12 cell studies In rodent models targeted injection into substantia nigra striatum or medial forebrain bundle leads to loss of tyrosine hydroxylase-positive neurons and resultant locomotor dysfunction resembling symptoms observed in Parkinson s disease Consequently it serves as a valuable tool for elucidating dopaminergic dysfunction mechanisms and evaluating therapeutic candidates
Cayman Chemical Clobenpropit hydrobromide
A selective histamine H3 receptor antagonist (Ki = 0.17 nM in rat cortical membranes); reduces inhibition of electrically induced contractions in isolated guinea pig ileum longitudinal muscle by (R)-α-methylhistamine at 0.3, 0.1, and 3 nM; decreases the duration of the tonic, clonic, and convulsive coma phases of electrically induced convulsions in mice at 1 and 3 mg/kg, an effect that can be blocked by (R)-α-methylhistamine or imetit; increases GABA release and inhibits NMDA-induced neurotoxicity in primary rat cortical neurons at 0.1 μM
Medchemexpress LLC Methanamine, N-(2,3-diphenyl-1,2,4-thiadiazol-5(2H)-ylidene)-, hydrobromide | 265980-25-4 | 96.81% | 348.26 | 1 MG
SCH-202676 hydrobromide is an allosteric modulator of G protein-coupled receptors (GPCRs) and adenosine receptor (AR). It has antiviral activity and inhibits 3CLpro in a time-dependent manner with an IC50 value of 0.655 μM.
- Allosteric modulator of G protein-coupled receptors (GPCRs) and adenosine receptor (AR).
- Has antiviral activity.
- Inhibits 3CLpro in a time-dependent manner with an IC50 value of 0.655 μM.
Medchemexpress LLC m-Tyramine hydrobromide | 38449-59-1 | 98.2% | 1 ML
m-Tyramine hydrobromide is an endogenous trace amine neuromodulator that affects adrenergic and dopaminergic receptors.
- Endogenous trace amine neuromodulator
- Affects adrenergic and dopaminergic receptors
- Appears as a solid, light yellow to yellow in color
- Molecular weight: 218.09
- Chemical formula: C8H12BrNO
- Classified as alkaloids and phenols
- Initial source is an endogenous metabolite
Medchemexpress LLC Burixafor (hydrobromide) | 1191450-19-7 | 98.0% | 769.01 | 50 MG
Burixafor hydrobromide is a potent CXCR4 antagonist with a pIC50 of 7.4. It inhibits CXCL12 binding to CXCR4, antagonizes Gαᵢ and β-arrestin2 recruitment, and blocks downstream Gαᵢ-mediated effects on cAMP signal transduction. This compound mobilizes CD34+ hematopoietic stem/progenitor cells (HSPC) for research on autologous hematopoietic stem cell transplantation (ASCT).
- Potent CXCR4 antagonist with a pIC50 of 7.4.
- Inhibits CXCL12 binding to CXCR4.
- Antagonizes CXCL12-induced Gαᵢ and β-arrestin2 recruitment.
- Blocks downstream Gαᵢ-mediated inhibitory effect on cAMP signal transduction.
- Mobilizes CD34+ hematopoietic stem/progenitor cells (HSPC).
- Useful for research on autologous hematopoietic stem cell transplantation (ASCT).