Hydrobromides
Medchemexpress LLC Fatostatin hydrobromide | 298197-04-3 | MFCD00760867 | 99.52% | C18H19BrN2S | 25 MG
Fatostatin hydrobromide (125B11 hydrobromide) is a specific inhibitor of SREBP activation. It impairs the activation of SREBP-1 and SREBP-2 by binding to SCAP (SREBP cleavage-activating protein), which inhibits the ER-Golgi translocation of SREBPs. This action leads to a decrease in the transcription of lipogenic genes in cells.
- Specific inhibitor of SREBP activation.
- Impairs activation of SREBP-1 and SREBP-2.
- Inhibits ER-Golgi translocation of SREBPs.
- Decreases transcription of lipogenic genes.
- Exhibits antitumor properties.
- Lowers hyperglycemia in ob/ob mice.
Medchemexpress LLC Galanthamine hydrobromide (Galantamine hydrobromide) | 1953-04-4 | 99.9% | C17H22BrNO3 | 500 MG
Galanthamine hydrobromide is a selective, reversible, competitive, alkaloid AChE inhibitor with an IC50 of 0.35 μM. It also acts as a potent allosteric potentiating ligand (APL) for human α3β4, α4β2, and α6β4 nicotinic receptors (nAChRs). This compound is primarily developed for research into Alzheimer's disease (AD).
- Selective, reversible, competitive alkaloid AChE inhibitor
- Potent allosteric potentiating ligand of human α3β4, α4β2, α6β4 nicotinic receptors (nAChRs)
- Developed for Alzheimer's disease (AD) research
- IC50 of 0.35 μM for AChE
eMolecules 849928-26-3 | 1-Boc-3-Bromopiperidine | ChemScene | MFCD07779077 | 264.163 | C10H18BrNO2 | 95.000 | CC(C)(C)OC(=O)N1CCCC(Br)C1 | 25g | 859848138
1-Boc-3-Bromopiperidine | ChemScene | 849928-26-3 | MFCD07779077 | 264.163 | C10H18BrNO2 | 95.000 | CC(C)(C)OC(=O)N1CCCC(Br)C1 | 25g | 859848138
eMolecules 180695-79-8 | 1-Boc-4-bromopiperidine | Accela ChemBio (ASD) | MFCD04115039 | 264.163 | C10H18BrNO2 | 97.000 | CC(C)(C)OC(=O)N1CCC(Br)CC1 | 25g | 444759518
1-Boc-4-bromopiperidine | Accela ChemBio (ASD) | 180695-79-8 | MFCD04115039 | 264.163 | C10H18BrNO2 | 97.000 | CC(C)(C)OC(=O)N1CCC(Br)CC1 | 25g | 444759518
eMolecules 180695-79-8 | N-Boc-4-bromopiperidine | ChemScene | MFCD04115039 | 264.163 | C10H18BrNO2 | 97.000 | CC(C)(C)OC(=O)N1CCC(Br)CC1 | 25g | 536904869
N-Boc-4-bromopiperidine | ChemScene | 180695-79-8 | MFCD04115039 | 264.163 | C10H18BrNO2 | 97.000 | CC(C)(C)OC(=O)N1CCC(Br)CC1 | 25g | 536904869
Medchemexpress LLC Arecaidine hydrobromide | 6013-57-6 | MFCD01692013 | 98.0% | 222.08 g/mol | C7H12BrNO2 | 10 MG
Arecaidine hydrobromide is the hydrobromide salt of arecaidine, a pyridine alkaloid that acts as a GABA uptake inhibitor. It is supplied as a research-grade reagent, typically with a reported purity of 98.0%, and is used in studies of GABA transport and related membrane transporter pathways.
- Suitable for research use only.
- Reported purity of 98.0% by supplier specification.
- Molecular formula C7H12BrNO2 and molecular weight 222.08 g/mol.
- Identified by CAS number 6013-57-6 for unambiguous substance lookup.
- Available in small research packs such as 10 mg for laboratory testing and screening.
TARGETMOL CHEMICALS INC REMODELIN HYDROBROMIDE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10. purity: 99%
Medchemexpress LLC Arecoline hydrobromide | 300-08-3 | 99.95% | 1 ML
Arecoline hydrobromide is a naturally brain-penetrant and orally active psychoactive alkaloid. It acts as a partial agonist of nicotinic and muscarinic acetylcholine receptors, exhibiting properties such as stimulation, alertness, anxiolysis, and anti-parasitic effects. It can also induce oxidative stress. This compound is for research use only.
- Acts as a partial agonist of nicotinic and muscarinic acetylcholine receptors
- Exhibits stimulation, alertness, anxiolysis, and anti-parasitic effects
- Can induce oxidative stress
- Brain-penetrant and orally active
- Induces reactive oxygen species generation and G1/G0 phase cell cycle arrest in HaCaT cells
- Upregulates stress-responsive genes
- Alleviates anxiety and depression in CFA-induced mice
Active Motif Arecoline hydrobromide
Active Motif's Arecoline hydrobromide is an inhibitor of acetyl-CoA acetyltransferase 1 (ACAT1). Tyrosine 407 phosphorylation activates mitochondrial acetyl-CoA ACAT1 by stabilizing its tetramer. This is believed to be the mechanisms by which ACAT1 is "hijacked" and contributes to the Warburg effect in cancer. Arecoline is a covalent inhibitor of ACAT1 which binds to and disrupts only ACAT1 tetramers (IC50 = 11.1 uM). ACAT2 and DLAT are not inhibited. Treatment of xenograft nude mice with Arecoline resulted in a dose-dependent reduction in tumor mass. It is an agonist at muscarinic acetylcholine receptors M1-M5 (EC50 in the range of 7-410 nM), and may be involved in dementia.
Apexbio Technology LLC A 61603 hydrobromide 107756-30-9 1mg
A 61603 hydrobromide (CAS 107756-30-9) is a potent and highly selective agonist of the 1A-adrenergic receptor one of the 1-adrenergic receptor subtypes involved in cellular growth and proliferation Compared to its activity at 1B- and 1D-adrenergic receptors A 61603 demonstrates approximately 35-fold higher potency for 1A-AR In cellular assays it robustly induces phosphoinositide hydrolysis in 1A-AR-expressing fibroblasts (pEC50 8 24) and in neonatal rat cardiomyocytes it increases calcium transient frequency in a dose-dependent manner (EC50 6 9 nM) In vascular models A 61603 markedly elevates perfusion pressure demonstrating significantly greater efficacy than noradrenaline This compound serves as a valuable tool for delineating 1A-AR-mediated signaling and vascular regulation