Hydrobromides
Apexbio Technology LLC Homatropine Bromide 51-56-9 5g
Homatropine Bromide (CAS 51-56-9) is a small molecule antagonist of muscarinic acetylcholine receptors (AChRs) It selectively inhibits muscarinic receptor-mediated responses in endothelial and smooth muscle cells with reported IC50 values of 162 5 nM and 170 3 nM for WKY-E and SHR-E cell models respectively This compound serves as a valuable tool for investigating the role of muscarinic signaling in vascular function and smooth muscle physiology within experimental research settings
TARGETMOL CHEMICALS INC FATOSTATIN HYDROBROMIDE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Fatostatin hydrobromide (Fatostatin A HBr) ia an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2. purity: 99%
Medchemexpress LLC Methanamine, N-(2,3-diphenyl-1,2,4-thiadiazol-5(2H)-ylidene)-, hydrobromide | 265980-25-4 | 96.81% | 348.26 | 1 MG
SCH-202676 hydrobromide is an allosteric modulator of G protein-coupled receptors (GPCRs) and adenosine receptor (AR). It has antiviral activity and inhibits 3CLpro in a time-dependent manner with an IC50 value of 0.655 μM.
- Allosteric modulator of G protein-coupled receptors (GPCRs) and adenosine receptor (AR).
- Has antiviral activity.
- Inhibits 3CLpro in a time-dependent manner with an IC50 value of 0.655 μM.
Medchemexpress LLC Arecoline hydrobromide | 300-08-3 | 99.9% | 100 MG
Arecoline hydrobromide is a naturally brain-penetrant and orally active psychoactive alkaloid. It functions as a partial agonist of nicotinic and muscarinic acetylcholine receptors, exhibiting stimulation, alertness, anxiolysis, and anti-parasitic effects. It can also induce oxidative stress.
- Acts as a partial agonist of nicotinic and muscarinic acetylcholine receptors
- Exhibits stimulation, alertness, anxiolysis, and anti-parasitic effects
- Induces generation of reactive oxygen species and cell cycle arrest in HaCaT cells
- Up-regulates stress-responsive genes
- Alleviates anxiety and depression in CFA-induced mice
Apexbio Technology LLC Arecoline hydrobromide 300-08-3 10mM (in 1mL DMSO)
Arecoline hydrobromide (CAS 300-08-3) is a nicotinic alkaloid that acts as a partial agonist at muscarinic acetylcholine receptors M1 M4 In electrophysiological studies it significantly inhibits the hERG potassium channel current with an IC50 of 9 55 mol/L The compound s inhibitory effect on IhERG displays concentration time and voltage dependency with blockade intensity influenced by stimulation frequency Subcutaneous administration in mice yields an LD50 of 100 mg/kg Arecoline hydrobromide is utilized in research on cardiac electrophysiology and muscarinic receptor pharmacology particularly for investigating frequency- and state-dependent modulation of cardiac ion channels
eMolecules 62595-74-8 | 3-bromopiperidine-2,6-dione | Pharmablock | MFCD11053059 | 192.012 | C5H6BrNO2 | 97.000 | BrC1CCC(=O)NC1=O | 2.5g | 686930241
3-bromopiperidine-2,6-dione | Pharmablock | 62595-74-8 | MFCD11053059 | 192.012 | C5H6BrNO2 | 97.000 | BrC1CCC(=O)NC1=O | 2.5g | 686930241
Medchemexpress LLC Remodelin hydrobromide | 1622921-15-6 | 99.6% | 363.28 | 50 MG
Remodelin hydrobromide is an orally active and selective inhibitor of acetyltransferase NAT10. It works by inhibiting NAT10 activity, which in turn slows down DNA replication and suppresses the growth of prostate cancer cells. This compound has been shown to inhibit the growth of both prostate cancer and hepatocellular carcinoma in xenograft models. Additionally, it enhances the healthspan in a mouse model of Hutchinson-Gilford progeria syndrome (HGPS).
- Orally active and selective inhibitor.
- Inhibits NAT10 activity.
- Slows DNA replication.
- Suppresses growth of prostate cancer cells.
- Inhibits growth of hepatocellular carcinoma in xenograft models.
- Enhances healthspan in a mouse model of HGPS.