Hydrobromides
Medchemexpress LLC Arecoline | 63-75-2 | 50 MG
Arecoline is a naturally occurring, brain-penetrant, and orally active psychoactive alkaloid. It acts as a partial agonist of both nicotinic and muscarinic acetylcholine receptors. It has been observed to induce stimulation, alertness, anxiolysis, and anti-parasitic effects, and can also induce oxidative stress.
- Naturally brain-penetrant and orally active psychoactive alkaloid.
- Partial agonist of nicotinic and muscarinic acetylcholine receptors.
- Exhibits stimulation, alertness, anxiolysis, and anti-parasitic effects.
- High purity: 99.84%.
Medchemexpress LLC Galanthamine hydrobromide | 1953-04-4 | 99.9% | C17H22BrNO3 | 1 ML
Galanthamine hydrobromide is a selective, reversible, competitive, alkaloid AChE inhibitor (IC50 0.35 μM) and a potent allosteric potentiating ligand (APL) for human α3β4, α4β2, α6β4 nicotinic receptors (nAChRs). It is developed for Alzheimer's disease (AD) research.
- Selective, reversible, competitive, alkaloid AChE inhibitor.
- Potent allosteric potentiating ligand (APL) of human nAChRs.
- Developed for Alzheimer's disease (AD) research.
- Demonstrates 53-fold selectivity for AChE over butyrylcholinesterase.
- Inhibits Aβ 1-40 and Aβ 1-42 aggregation (50 μM).
- Protects against Aβ(1-40) and Aβ(1-42) toxicity in SH-SY5Y cells.
- Reduces Aβ(1-40)-induced cellular apoptosis.
- Reduces cognitive deficits in APP23 mice.
Medchemexpress LLC NAN-190 hydrobromide | 115338-32-4 | 99.1% | 474.39 | 10 MG
NAN-190 hydrobromide is a serotonin receptor 5-HT antagonist, specifically a selective antagonist of 5-HT1A receptors. It is primarily used for research purposes and has been shown to reverse the catalepsy-improving effect of fluoxetine in 6-OHDA lesioned rats.
- Serotonin receptor 5-HT antagonist
- Selective antagonist of 5-HT1A receptor
- Reverses catalepsy-improving effect of fluoxetine
- For research use only
eMolecules 62595-74-8 | 3-Bromopiperidine-2,6-dione | Synthonix - Stock | MFCD11053059 | 192.012 | C5H6BrNO2 | 97.000 | BrC1CCC(=O)NC1=O | 1g | 476497459
3-Bromopiperidine-2,6-dione | Synthonix - Stock | 62595-74-8 | MFCD11053059 | 192.012 | C5H6BrNO2 | 97.000 | BrC1CCC(=O)NC1=O | 1g | 476497459
Medchemexpress LLC S-(2-aminoethyl) methanethiosulfonate hydrobromide | 16599-33-0 | 97.9% | 25 MG
MTSEA hydrobromide is a sulfhydryl-reactive reagent that selectively modifies free cysteine residues to introduce a positively charged side chain roughly the size of lysine. It is used in biochemical and electrophysiological studies to probe cysteine accessibility and to introduce charge at engineered cysteine sites.
- Sulfhydryl-reactive reagent for targeted cysteine modification.
- High supplied purity of 97.9%.
- Molecular weight 236.15 g/mol; formula C3H10BrNO2S2.
- Available in small solid packs suitable for research use.
- Store sealed at -20°C; in solution store at -80°C for long-term stability.
- CAS number 16599-33-0 for unambiguous identification.
Apexbio Technology LLC Imetit dihydrobromide 32385-58-3 10mg
Imetit dihydrobromide (CAS 32385-58-3) is a potent high-affinity agonist of histamine H3 and H4 receptors demonstrating Ki values of 0 3 nM and 2 7 nM respectively Functionally it replicates histaminergic effects by inducing morphological changes in eosinophils with an EC50 of 25 nM Owing to its selective receptor activity Imetit dihydrobromide is widely employed in studies investigating allergic inflammatory processes including asthma as well as in research focused on central nervous system physiology and histamine-related pathways
Medchemexpress LLC Guvacoline hydrobrom 10mg | 17210-51-4 | 222.08 g·mol⁻1 | C7H12BrNO2 | 10 MG
Guvacoline hydrobromide is the hydrobromide salt of guvacoline, a pyridine alkaloid that acts as a weak full agonist at atrial and ileal muscarinic acetylcholine receptors. This research-grade solid is provided for in vitro pharmacology and receptor-binding studies.
- High purity (96.09%) research-grade material.
- Molecular weight 222.08 g·mol⁻1; formula C7H12BrNO2.
- Suitable for muscarinic receptor pharmacology and neuropharmacology assays.
- Supplied as a 10 mg solid for small-scale experimental use.
Apexbio Technology LLC BD 1047 dihydrobromide 138356-21-5 50mg
BD 1047 dihydrobromide (CAS 138356-21-5) is a selective antagonist of the sigma-1 ( 1) receptor exhibiting Ki values of 0 93 nM for 1 and 47 nM for sigma-2 ( 2) receptors Sigma receptors distinct from opioid receptors include 1 and 2 subtypes and are implicated in modulating dopaminergic neurotransmission and drug-related behaviors In preclinical models BD 1047 dihydrobromide attenuates haloperidol- and DTG-induced dystonia and reverses cocaine-induced behavioral responses without affecting responses to natural rewards Additionally it alleviates mechanical allodynia in neuropathic pain models and modulates spinal 1 receptor and NR1 subunit expression This compound is utilized to investigate 1 receptor function in neuropharmacology and pain research
Medchemexpress LLC Sulfone, bis((4-chloroacetylamino)phenyl). | 17328-16-4 | MFCD00028183 | 98.0% | 401.26 g/mol | C16H14Cl2N2O4S | 1 ML
TC-E 5003 is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor supplied as a ready-to-use 10 mM solution in DMSO for research use in biochemical and cell-based assays. Handle and store according to laboratory safety and storage guidelines.
- Selective PRMT1 inhibitor with reported IC50 ≈ 1.5 μM.
- Supplied as a 10 mM solution in DMSO, 1 mL vial.
- Purity 98.0% by HPLC.
- Molecular weight 401.26 g/mol.
- Store solution at -80°C for long-term stability; short-term storage at -20°C.
Medchemexpress LLC Scopolamine hydrobromide trihydrate | 6533-68-2 | MFCD00150066 | 99.86% | 438.31 | 50 MG
Scopolamine hydrobromide trihydrate, also known as Hyoscine hydrobromide trihydrate, is a potent muscarinic antagonist capable of crossing the blood-brain barrier. It competitively antagonizes 5-HT3 receptors with an IC50 of 2.09 μM. This compound has been observed to induce cognitive and memory deficits in animals. It is currently being investigated for its potential applications in the prevention of postoperative nausea and vomiting, motion sickness, and nervous system diseases.
- High-affinity muscarinic antagonist.
- Able to cross the blood-brain barrier.
- Competitively antagonizes 5-HT3 receptors.
- Used in research for preventing postoperative nausea and vomiting.
- Used in research for motion sickness.
- Used in research for nervous system diseases.
Medchemexpress LLC Vortioxetine (hydrobromide) | 960203-27-4 | C18H23BrN2S | 1 G
Vortioxetine hydrobromide (Lu AA 21004) is a multimodal serotonergic agent that acts as an antagonist of 5-HT3A (Ki: 3.7 nM) and 5-HT7 (Ki: 19 nM) receptors. It also inhibits the 5-hydroxytryptamine transporter (SERT) with a Ki of 1.6 nM. Furthermore, it functions as a 5-HT1A agonist (Ki: 15 nM) and a partial 5-HT1B agonist (Ki: 33 nM), exhibiting potent inhibition of SERT.
- Antagonist of 5-HT3A and 5-HT7 receptors
- Inhibitor of 5-hydroxytryptamine transporter (SERT)
- Acts as a 5-HT1A agonist
- Functions as a partial 5-HT1B agonist
- High purity of 99.87%
- Light yellow to yellow solid appearance
Medchemexpress LLC L-2,4-diaminobutyric acid hydrobromide | 73143-97-2 | MFCD07368664 | 98.0% | 199.05 g/mol | C4H11BrN2O2 | 500 MG
L-2,4-diaminobutyric acid hydrobromide (L-DABA hydrobromide) is a research chemical described as a weak GABA transaminase inhibitor (IC50 > 500 μM) and reported to exhibit antitumor activity in vitro and in vivo. It is supplied as the hydrobromide salt, CAS 73143-97-2, with molecular weight 199.05 g/mol and reported purity 98.0%.
- High purity: 98.0%.
- Reported activity: weak GABA transaminase inhibitor (IC50 > 500 μM).
- Demonstrated antitumor activity in vitro and in vivo.
- Provided as hydrobromide salt for research use.
- Available in 500 mg pack size.
eMolecules 768-66-1 | 2,2,6,6-Tetramethylpiperidine | Combi-Blocks | MFCD00005985 | 141.258 | C9H19N | 95.000 | CC1(C)CCCC(C)(C)N1 | 5g | 296391144
2,2,6,6-Tetramethylpiperidine | Combi-Blocks | 768-66-1 | MFCD00005985 | 141.258 | C9H19N | 95.000 | CC1(C)CCCC(C)(C)N1 | 5g | 296391144
Apexbio Technology LLC Homatropine Methylbromide 80-49-9 10mM (in 1mL DMSO)
Homatropine Methylbromide (CAS 80-49-9) is a small molecule antagonist of muscarinic acetylcholine receptors (AChRs) It inhibits muscarinic signaling by blocking receptor activity on endothelial and smooth muscle cells as demonstrated in WKY-E and SHR-E models with IC50 values of 162 5 nM and 170 3 nM respectively This compound is utilized in studies investigating cholinergic modulation of vascular tone and smooth muscle function offering a tool for dissecting the roles of muscarinic receptors in cardiovascular and autonomic research contexts
Ambeed 2-BROMOMETHYL PYRIDINE HYDROB
2-(Bromomethyl)pyridine hydrobromide-5 gramsCAS No.: 31106-82-8Ambeed