Hydrobromides
TARGETMOL CHEMICALS INC Halofuginone hydrobromide 10MG
Also available in 1 mL, 1 mg, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor cell growth. Halofuginone Hydrobromide is the hydrobromide salt of halofuginone, a semisynthetic quinazolinone alkaloid anticoccidial derived from the plant Dichroa febrifuga, with antifibrotic and potential antineoplastic activities. These effects appear to be due to halofuginone-mediated inhibition of the collagen type I and MMP-2 promoters. Collagen type I and MMP-2 play important roles in fibroproliferative diseases. Purity 98.5%
Medchemexpress LLC Remodelin (hydrobromide) | 1622921-15-6 | 99.6% | 363.28 | 500 MG
Remodelin hydrobromide is an orally active and selective inhibitor of acetyltransferase NAT10. It inhibits NAT10 activity, slows DNA replication, and suppresses the growth of prostate cancer cells. It also inhibits the growth of prostate cancer and hepatocellular carcinoma in xenograft models. Additionally, it enhances the healthspan in a Hutchinson-Gilford Progeria Syndrome (HGPS) mouse model.
- Orally active and selective inhibitor of acetyltransferase NAT10.
- Inhibits NAT10 activity.
- Slows DNA replication.
- Suppresses growth of prostate cancer cells.
- Inhibits the growth of prostate cancer and hepatocellular carcinoma in xenograft model.
- Enhances healthspan in Hutchinson-Gilford Progeria Syndrome (HGPS) mouse model.
Cayman Chemical FenoterolhydrobromIde 10mg
An analytical reference standard categorized as a β2-adrenergic receptor agonist; has been used as a performance-enhancing drug in sports doping and is banned by WADA; intended for research and forensic applications
Medchemexpress LLC Halofuginone hydrobromide | 64924-67-0 | 495.59 | 100 MG
Halofuginone hydrobromide (RU-19110 hydrobromide) is a competitive prolyl-tRNA synthetase inhibitor. This Febrifugine derivative acts as a specific inhibitor of type-I collagen synthesis and helps in attenuating osteoarthritis by inhibiting TGF-β activity. It also functions as a potent pulmonary vasodilator through the activation of Kv channels and blocking voltage-gated, receptor-operated, and store-operated Ca2+ channels.
- Acts as a competitive prolyl-tRNA synthetase inhibitor.
- Inhibits type-I collagen synthesis.
- Attenuates osteoarthritis by inhibiting TGF-β activity.
- Functions as a potent pulmonary vasodilator.
- Activates Kv channels.
- Blocks voltage-gated, receptor-operated, and store-operated Ca2+ channels.
- Possesses anti-malaria effects.
- Demonstrates anti-inflammatory properties.
- Exhibits anti-cancer and anti-fibrosis effects.
Apexbio Technology LLC SR 95531 hydrobromide 104104-50-9 25mg
SR 95531 hydrobromide (CAS 104104-50-9) also known as Gabazine is a selective competitive antagonist of the GABAA receptor By binding to the GABA recognition site on the receptor it blocks the activation induced by -aminobutyric acid (GABA) Experimental studies report an inhibitory concentration (IC50) of approximately 0 2 M for GABAA receptor-mediated responses Widely utilized in neuroscience research Gabazine is applied to investigate the physiological and pathological roles of GABAA receptor-mediated synaptic transmission neural network modulation and neurotransmitter regulation
Medchemexpress LLC Oxidopamine (hydrobromide) | 636-00-0 | 99.4% | 500 MG
Oxidopamine (6-OHDA) hydrobromide is a potent neurotoxin that selectively destroys dopaminergic neurons by acting as an antagonist of the neurotransmitter dopamine. It is a valuable tool for research into various neurological conditions, including Parkinson's disease (PD), attention-deficit hyperactivity disorder (ADHD), and Lesch-Nyhan syndrome. The compound also promotes COX-2 activation, leading to PGE2 synthesis and pro-inflammatory cytokine IL-1β secretion.
- Selectively destroys dopaminergic neurons
- Antagonist of dopamine neurotransmitter
- Promotes COX-2 activation and PGE2 synthesis
- Induces pro-inflammatory cytokine IL-1β secretion
- Useful for Parkinson's disease research models
- Applicable in ADHD and Lesch-Nyhan syndrome studies
Medchemexpress LLC Fenoterol hydrobromide | 1944-12-3 | 100.0% | 1 ML
Fenoterol hydrobromide (Th-1165a) is a sympathomimetic agent that acts as a selective and orally active β2-adrenoceptor agonist. It is an effective bronchodilator, making it suitable for research into bronchospasm associated with asthma, bronchitis, and other obstructive airway diseases.
- Selective and orally active β2-adrenoceptor agonist
- Functions as an effective bronchodilator
- Used in research for bronchospasm associated with asthma, bronchitis, and other obstructive airway diseases
Medchemexpress LLC Halofuginone hydrobromide | 64924-67-0 | MFCD00946455 | 100.0% | 495.59 g·mol⁻¹ | C16H18Br2ClN3O3 | 10 MG
Halofuginone hydrobromide is a febrifugine derivative and a competitive prolyl-tRNA synthetase inhibitor used as a research standard for studies of collagen synthesis, TGF-β signaling, fibrosis, cancer biology, and anti-parasitic activity.
- Competitive prolyl-tRNA synthetase inhibitor with reported Ki ≈ 18.3 nM.
- Inhibits type-I collagen synthesis, useful for fibrosis and TGF-β studies.
- High reported purity (99.99%), suitable as a reference standard.
- Characterized molecular weight (495.59 g·mol⁻¹) and CAS number (64924-67-0).
- Available in small mg quantities for in vitro and pharmacological assays.
Medchemexpress LLC 1,4-PBIT (dihydrobromide) | 157254-60-9 | 98.0% | 444.25 g·mol⁻¹ | C12H20Br2N4S2 | 5 MG
1,4-PBIT (dihydrobromide) is a research-grade small-molecule inhibitor of nitric oxide synthases provided as the dihydrobromide salt (CAS 157254-60-9). Supplied in small-mass vials for biochemical and pharmacological studies, the compound is characterized by analytical documentation and high purity suitable for in vitro research.
- Potent inhibitor of iNOS, eNOS, and nNOS isoforms.
- High purity for reliable experimental results.
- Available in small-mass vials suitable for medicinal chemistry applications.
- Stable dihydrobromide salt form for consistent handling.
- Documented analytical data and certificate of analysis available.
Medchemexpress LLC Amthamine dihydrobromide | 142457-00-9 | MFCD00673891 | 99.6% | 319.07 g/mol | C6H13Br2N3S | 10 MG
Amthamine dihydrobromide is the dihydrobromide salt of amthamine, a histamine receptor agonist active at H1-H4 subtypes. It is supplied for research use to investigate histamine receptor pharmacology, gastric acid secretion, and hepatotoxicity models. Follow standard laboratory safety and storage recommendations.
- High purity (99.6%) suitable for biochemical and pharmacological studies.
- Molecular weight 319.07 g/mol.
- Chemical formula C6H13Br2N3S.
- CAS number 142457-00-9 for unambiguous identification.
- Available in small research quantities, such as 10 MG, for laboratory use.
- Stable when stored sealed and kept away from moisture; refrigerated storage extends stability.
Medchemexpress LLC Darifenacin hydrobromide | 133099-07-7 | MFCD08141803 | 99.8% | C28H31BrN2O2 | 50 MG
Darifenacin hydrobromide is a selective and orally active M3 muscarinic receptor (M3R) antagonist. It exhibits high specificity for M3R, binding >20-fold more specifically than to other muscarinic receptors. This compound is valuable for studying urinary incontinence and other symptoms associated with an overactive bladder. Additionally, it has demonstrated potential in inhibiting tumor growth in colorectal cancer cells, suggesting anti-tumor effects.
- Selective and orally active M3 muscarinic receptor antagonist
- High specificity for M3R
- Useful in studying urinary incontinence and overactive bladder
- Inhibits tumor growth in colorectal cancer cells
- Exhibits anti-tumor effects
Medchemexpress LLC Oxidopamine hydrobromide | 636-00-0 | 99.42% | 100 MG
Oxidopamine (6-OHDA) hydrobromide is an antagonist of the neurotransmitter dopamine. It is a widely used neurotoxin that selectively destroys dopaminergic neurons. It promotes COX-2 activation, leading to PGE2 synthesis and pro-inflammatory cytokine IL-1β secretion. Oxidopamine hydrobromide can be used for the research of Parkinson's disease (PD), attention-deficit hyperactivity disorder (ADHD), and Lesch-Nyhan syndrome.
- Antagonist of the neurotransmitter dopamine.
- Widely used neurotoxin.
- Selectively destroys dopaminergic neurons.
- Promotes COX-2 activation.
- Leads to PGE2 synthesis and pro-inflammatory cytokine IL-1β secretion.
- Used for research of Parkinson's disease (PD), attention-deficit hyperactivity disorder (ADHD), and Lesch-Nyhan syndrome.
Medchemexpress LLC Oxidopamine (hydrobromide) | 636-00-0 | 99.4% | 50 MG
Oxidopamine (6-OHDA) hydrobromide is a neurotoxin that selectively destroys dopaminergic neurons and acts as an antagonist of the neurotransmitter dopamine. It promotes COX-2 activation, leading to PGE2 synthesis and pro-inflammatory cytokine IL-1β secretion. This compound is used in research for Parkinson's disease (PD), attention-deficit hyperactivity disorder (ADHD), and Lesch-Nyhan syndrome.
- Antagonist of the neurotransmitter dopamine.
- Selectively destroys dopaminergic neurons.
- Promotes COX-2 activation, leading to PGE2 synthesis and pro-inflammatory cytokine IL-1β secretion.
- Used for research of Parkinson's disease (PD), attention-deficit hyperactivity disorder (ADHD), and Lesch-Nyhan syndrome.
- Can induce Parkinson's disease models.
Medchemexpress LLC Anisodamine hydrobromide | 55449-49-5 | 99.5% | 386.28 g/mol | C17H24BrNO4 | 10 MG
Anisodamine hydrobromide is the hydrobromide salt of anisodamine (6-hydroxyhyoscyamine), a belladonna alkaloid with muscarinic and nicotinic receptor activity. It is supplied as a high-purity research reagent for pharmacology and biochemical studies; not for clinical use.
- High purity (approximately 99.5%).
- Molecular weight 386.28 g/mol.
- Hydrobromide salt increases water solubility for aqueous assays.
- Supplied in small milligram quantities suitable for analytical and preclinical research.
- Commonly used in muscarinic receptor pharmacology and biochemical research applications.
![Medchemexpress LLC Piperidine, 4-[2-[(4-methylphenyl)thio]phenyl]-, hydrobromide | 960151-65-9 | 99.8% | 364.34 g/mol | C18H22BrNS | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000249020.png-250.jpg)
Medchemexpress LLC Piperidine, 4-[2-[(4-methylphenyl)thio]phenyl]-, hydrobromide | 960151-65-9 | 99.8% | 364.34 g/mol | C18H22BrNS | 1 ML
Tedatioxetine hydrobromide is the hydrobromide salt of tedatioxetine, a serotonin- and norepinephrine-preferring triple reuptake inhibitor that also antagonizes 5-HT2A, 5-HT2C, 5-HT3, and α1A-adrenergic receptors. It is supplied for research use as a solid and as a 10 mM solution in DMSO, intended for in vitro transporter and receptor pharmacology studies.
- High purity (99.83%) suitable for research applications.
- Supplied as solid and as a 10 mM solution in DMSO (1 mL).
- Suitable for transporter and receptor pharmacology assays.
- Molecular formula C18H22BrNS; molecular weight 364.34 g/mol.
- Store sealed, away from moisture; in solvent: -80°C (6 months) or -20°C (1 month).