Hydrochlorides
Medchemexpress LLC Cp-409092 hydrochloride | 225240-86-8 | 99.8% | 333.81 g/mol | C17H20ClN3O2 | 25 MG
CP-409092 hydrochloride is a research chemical that functions as a partial agonist of the GABAA receptor and has reported anxiolytic activity. Supplied as the hydrochloride salt, it is provided as a high-purity solid for in vitro and in vivo pharmacology studies.
- Acts as a partial agonist of the GABAA receptor.
- Demonstrates reported anti-anxiety (anxiolytic) activity in pharmacological assays.
- High purity (≈99.8%) with white to off-white solid appearance.
- Soluble in water and DMSO with ultrasonic assistance for stock preparation.
- Documented with COA, SDS, and data sheet for research handling.
Medchemexpress LLC Cyclopentanecarboxylic acid, 1-(4-nitrophenyl)-, 2-(diethylamino)ethyl ester, hydrochloride | 98636-73-8 | MFCD00673872 | 99.6% | 370.87 g/mol | C18H27ClN2O4 | 25 MG
Nitrocaramiphen hydrochloride is a selective M1 muscarinic receptor antagonist supplied as the hydrochloride salt for research use. It inhibits muscarine-induced hyperpolarization in muscle fibers and is provided as a white to off-white solid suitable for biochemical and pharmacological studies.
- Selective M1 receptor antagonist (Ki: 5.5 nM).
- High purity: 99.6% (manufacturer COA).
- White to off-white solid, molecular formula C18H27ClN2O4.
- Molecular weight 370.87 g/mol.
- Available in small milligram quantities for research use.
- Store sealed away from moisture; in solvent: -80°C (6 months), -20°C (1 month).
Medchemexpress LLC Ynt-185 | 1804978-81-1 | 98.5% | 615.74 | 1 ML
YNT-185 is a nonpeptide, selective orexin type-2 receptor (OX2R) agonist. It has EC50s of 0.028 μM for OX2R and 2.75 μM for OX1R. YNT-185 has been shown to ameliorate narcolepsy-cataplexy symptoms in mouse models. It is for research use only and not sold to patients.
- Selectively activates the orexin type-2 receptor
- Ameliorates narcolepsy-cataplexy symptoms in mouse models
- Increases wakefulness in mice
- Significantly increases wake time in a dose-dependent manner
Medchemexpress LLC Fipexide hydrochloride | 34161-23-4 | 99.9% | 50 MG
Fipexide hydrochloride is a parachloro-phenossiacetic acid derivative and an orally active nootropic agent. It reduces striatal adenylate cyclase activity and positively affects cognitive performance through dopaminergic neurotransmission. Fipexide hydrochloride is used for senile dementia research. It also acts as a chemical inducer in callus formation, shoot regeneration, and Agrobacterium infection.
- Reduces striatal adenylate cyclase activity.
- Positively affects cognitive performance.
- Used in senile dementia research.
- Acts as a chemical inducer in callus formation, shoot regeneration, and Agrobacterium infection.
- Abolishes memory deficits produced by kindling.
Medchemexpress LLC Naloxone hydrochloride (standard) | 357-08-4 | 99.7% | 363.84 | 50 MG
Naloxone hydrochloride (Standard) is the analytical standard of Naloxone hydrochloride, intended for research and analytical applications. It functions as an antagonist of the Opioid receptor and is known to alleviate opioid-overdose-induced respiratory depression. This compound is a reference standard supplied for assay and is commonly used in qualitative, quantitative, and methodological research experiments.
- Used for research and analytical applications.
- Functions as an Opioid receptor antagonist.
- Alleviates opioid-overdose-induced respiratory depression.
- Suitable for HPLC, GC, and MS experiments.
- Reference standard grade for assay.
Medchemexpress LLC Urapidil (hydrochloride) | 64887-14-5 | MFCD00078601 | 99.98% | 100 MG
Urapidil hydrochloride (Standard) is an analytical standard intended for research and analytical applications. It is an orally active α1-adrenoceptor antagonist and 5-HT1A receptor agonist, showing an antihypertensive effect.
- Analytical standard grade
- Used in qualitative research experiments
- Used in quantitative research experiments
- Used in methodological research experiments
- Applicable in HPLC
- Applicable in GC
- Applicable in MS
Medchemexpress LLC XE991 dihydrochloride | 122955-13-9 | 99.6% | 449.37 | 10 MG
XE991 dihydrochloride is a Kv7 (KCNQ) channels blocker. It potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channels, and M-current with IC50s of 0.75 μM, 0.71 μM, 0.6 μM, and 0.98 μM, respectively. This compound is designed for research applications.
- Potent Kv7 (KCNQ) channels blocker
- Inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channels, and M-current
- Enhances [3H]ACh release from rat brain slices with an EC50 of 490 nM
- Demonstrates good in vivo potency and duration of action
- For research use only
Medchemexpress LLC Dptn dihydrochloride | 325767-87-1 | 98.5% | 459.39 g/mol | C22H20Cl2N4OS | 10 MG
DPTN dihydrochloride is a research-grade dihydrochloride salt that functions as a potent, selective antagonist of the adenosine A3 receptor (A3AR) in human, mouse, and rat. It is supplied as a solid for in vitro and receptor-binding studies and is intended for research use only.
- Potent A3AR antagonist with high affinity (hA3 Ki = 1.65 nM; mouse = 9.61 nM; rat = 8.53 nM).
- High purity suitable for biochemical assays (98.47%).
- Solid, light yellow to yellow physical form for easy handling.
- Soluble in DMSO (~5 mg/mL) with ultrasonic warming recommended.
- Stable when stored sealed at -20°C; in solution store at -80°C for long-term.
Medchemexpress LLC 4-(4-fluoronaphthalen-1-yl)-6-propan-2-ylpyrimidin-2-amine | 199864-87-4 | MFCD20270616 | 100.0% | 281.33 g/mol | C17H16FN3 | 10 MG
RS-127445 is a selective, high-affinity 5-HT2B receptor antagonist used in preclinical research. It is orally bioavailable, shows a pKi of 9.5, and is supplied as a white to off-white solid suitable for both in vitro and in vivo studies. Intended for laboratory research use only.
- Selective 5-HT2B receptor antagonist with nanomolar affinity.
- Orally bioavailable and active in vivo models.
- High chemical purity suitable for analytical and biological assays.
- Available as a solid for convenient weighing and formulation.
- Suitable for in vitro potency and selectivity profiling.
Medchemexpress LLC SB-399885 hydrochloride | 402713-81-9 | MFCD09970355 | 98.3% | 482.81 g·mol⁻¹ | C18H22Cl3N3O4S | 50 MG
SB-399885 hydrochloride is the hydrochloride salt of SB-399885, a selective 5-HT6 (serotonin 6) receptor antagonist supplied for research use. It is provided as a high-purity solid and is available as a ready-to-use solution in DMSO, for use in in vitro and in vivo pharmacological studies.
- Selective 5-HT6 receptor antagonist.
- High reported purity (~98.3%).
- Hydrochloride salt form for improved stability and solubility.
- Available as solid and 10 mM solution in DMSO.
- Suitable for in vitro and in vivo pharmacology studies.
Medchemexpress LLC TAK-960 dihydrochloride | 1137868-52-0 | C27H36Cl2F3N7O3 | 50 MG
TAK-960 dihydrochloride is an orally available, selective inhibitor of polo-like kinase 1 (PLK1), with an IC50 of 0.8 nM. It also shows inhibitory activities against PLK2 and PLK3, with IC50s of 16.9 and 50.2 nM, respectively. This compound inhibits the proliferation of multiple cancer cell lines and exhibits significant efficacy against multiple tumor xenografts.
- Causes accumulation of G2-M cells, aberrant polo mitosis morphology, and increased phosphorylation of histone H3 (pHH3).
- Inhibits proliferation of multiple cancer cell lines (e.g., HT-29, HCT116, HeLa) with mean EC50 values from 8.4 to 46.9 nM, not affecting normal cells.
- In HeLa cells, 8 nM leads to G2/M cell cycle arrest without significant cytotoxicity.
- In animal models, it shows substantial antitumor activity and good tolerability against HT-29 colorectal cancer xenografts.
Medchemexpress LLC Zt 52656a hydrochloride | 115730-24-0 | 99.98% | 390.87 | C19H26ClF3N2O | 10 MG
ZT 52656A hydrochloride is the hydrochloride salt of a selective kappa-opioid receptor agonist used in research on kappa opioid receptor pharmacology. It is reported for prevention or alleviation of ocular pain and is supplied for in vitro and in vivo experimental use.
- Selective kappa-opioid receptor agonist, useful for KOR pharmacology studies.
- High reported purity of 99.98% for consistent experimental results.
- Chemical formula C19H26ClF3N2O and molecular weight 390.87 aid in dosing and calculations.
- Available in multiple pack sizes and as a DMSO solution for flexible experimental use.
- Provided as the hydrochloride salt to improve solubility in aqueous media.