Hydrochlorides
Medchemexpress LLC ASP-4058 hydrochloride | 952510-14-4 | 99.7% | 478.78 | 25 MG
ASP-4058 hydrochloride is a next-generation, selective, and orally active agonist for Sphingosine 1-Phosphate receptors 1 and 5 (S1P1 and S1P5). This compound has been shown to ameliorate rodent experimental autoimmune encephalomyelitis with a favorable safety profile.
- Next-generation S1P1 and S1P5 agonist
- Selective and orally active
- Ameliorates rodent experimental autoimmune encephalomyelitis
- Favorable safety profile
Medchemexpress LLC VU 0364439 | 1246086-78-1 | C18H13Cl2N3O3S | 1 MG
VU 0364439 is a mGlu4 positive allosteric modulator (PAM) with an EC50 of 19.8 nM. It is for research use only. The compound shows better stability in HLM (63% remaining) than RLM (2% remaining). It is a positive allosteric modulator of human mGlu4 receptor expressed in CHO cells, assessed as potentiation of glutamate-induced calcium mobilization. The appearance is a solid, white to off-white.
- Positive allosteric modulator of human mGlu4 receptor
- EC50 of 19.8 nM
- Better stability in HLM (63% remaining) than RLM (2% remaining)
- Appearance: Solid, white to off-white
- For research use only
Medchemexpress LLC Nylidrin hydrochloride | 849-55-8 | 98.7% | 335.87 g·mol⁻¹ | C19H26ClNO2 | 10 MG
Nylidrin hydrochloride is the hydrochloride salt of buphenine, a research-grade β-adrenergic agonist with reported NMDA NR1A/2B antagonism and antiviral activity against H1N1 influenza. It is used in receptor pharmacology and preclinical models of hemorrhagic shock and allergic responses.
- Orally active β-adrenergic agonist for receptor pharmacology studies.
- Reported NMDA NR1A/2B antagonist activity.
- Demonstrated antiviral activity against multiple H1N1 influenza A subtypes.
- Used in hemorrhagic shock and anti-allergic research models.
- High-purity research reagent suitable for analytical and in vivo studies.
Medchemexpress LLC Cp-409092 Hydrochlor 10Mm 1Ml | HY-101639A-10MM 1ML
Cp-409092 Hydrochlor 10Mm 1Ml
Medchemexpress LLC Piperoxan hydrochloride | 135-87-5 | MFCD00079224 | ≥98% | 269.77 g/mol | C14H20ClNO2 | 1 ML
Piperoxan hydrochloride is an α2 adrenoceptor antagonist and first-generation antihistamine supplied as a 10 mM solution in DMSO (1 mL) for research use. It is identified by CAS 135-87-5 and has a molecular weight of 269.77 g/mol. The ready-to-use format is intended for in vitro receptor pharmacology and small-scale assay applications.
- Ready-to-use 10 mM solution in DMSO.
- Suitable for adrenergic receptor and antihistamine research.
- Supplied at 1 mL volume for small-scale assays.
- Molecular weight 269.77 g/mol; CAS 135-87-5.
- Reported high purity (≥98%) in supplier documentation.
Medchemexpress LLC GKT136901 hydrochloride | 1254507-01-1 | 99.9% | 403.26 g/mol | C19H16Cl2N4O2 | 1 ML
GKT136901 hydrochloride is a research-grade small-molecule inhibitor selective for NADPH oxidase isoforms NOX1 and NOX4. It is used in preclinical studies to investigate oxidative stress, inflammation, and related disease models such as diabetic nephropathy, stroke, and neurodegeneration. The hydrochloride salt is supplied as a solid or as a 10 mM solution in DMSO for biochemical and cell-based assays.
- Selective NOX1/4 inhibition for targeted research applications.
- Potent activity (Ki ≈ 160 nM) for effective pathway modulation.
- Available as a 10 mM solution in DMSO for ready-to-use assays.
- High chemical purity to support reproducible results.
- Supplied as a stable solid with recommended cold storage.
- Suitable for biochemical and cell-based experimental workflows.
Medchemexpress LLC Rx 801077 hydrochloride | 89196-95-2 | 99.8% | 222.67 g/mol | C11H11ClN2O | 50 MG
RX 801077 hydrochloride (2 BFI) is a selective imidazoline I2 receptor agonist used in neuroscience research. It exhibits nanomolar binding affinity to I2 receptors and has been reported to show anti-inflammatory and neuroprotective effects relevant to traumatic brain injury and receptor pharmacology studies.
- Selective imidazoline I2 receptor agonist.
- High purity: 99.8%.
- Hydrochloride salt for improved stability and handling.
- Suitable for in vitro and in vivo pharmacology research.
- Molecular weight: 222.67 g/mol.
- Reported anti-inflammatory and neuroprotective activity.
- Available as a 50 MG research-size package.
eMolecules 21987-29-1 | 4,4-DIFLUOROPIPERIDINE | AstaTech | MFCD03094281 | 121.131 | C5H9F2N | 95.000 | FC1(F)CCNCC1 | 1g | 261434922
4,4-DIFLUOROPIPERIDINE | AstaTech | 21987-29-1 | MFCD03094281 | 121.131 | C5H9F2N | 95.000 | FC1(F)CCNCC1 | 1g | 261434922
eMolecules 6291-01-6 | Cyclobutanamine hydrochloride | ChemScene | MFCD00034953 | 107.580 | C4H10ClN | 97.000 | Cl.NC1CCC1 | 10g | 536772988
Cyclobutanamine hydrochloride | ChemScene | 6291-01-6 | MFCD00034953 | 107.580 | C4H10ClN | 97.000 | Cl.NC1CCC1 | 10g | 536772988
eMolecules 912999-79-2 | 5-Chloroisoindoline hydrochloride | Ambeed | MFCD11223562 | 190.07 | C8H9Cl2N | 98 | Cl.Clc1ccc2CNCc2c1 | 5g | 552537975
5-Chloroisoindoline hydrochloride | Ambeed | 912999-79-2 | MFCD11223562 | 190.070 | C8H9Cl2N | 98.000 | Cl.Clc1ccc2CNCc2c1 | 5g | 552537975
Medchemexpress LLC Nisoxetine | 53179-07-0 | MFCD00865443 | 98.6% | 271.35 | C17H21NO2 | 10 MG
Nisoxetine is a selective norepinephrine transporter (NET) inhibitor intended for research use. It is supplied as a high-purity solid suitable for pharmacology, binding, and analytical studies.
- Selective norepinephrine transporter inhibitor for research use only.
- High purity (≈98.6%) suitable for analytical assays.
- Molecular weight 271.35 and formula C17H21NO2.
- Available in sizes from 5-500 mg to support assay scale-up.
- Supplied with analytical documentation (COA, LCMS, NMR, SDS).
Apexbio Technology LLC VU 0361737 1161205-04-4 5mg
VU 0361737 (CAS 1161205-04-4) is a selective brain-penetrant positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4) It demonstrates high selectivity for mGluR4 over other mGluR subtypes with EC50 values of 240 nM for human and 110 nM for rat mGluR4 and shows minimal to no activity at mGluR1 mGluR2 mGluR3 mGluR6 and mGluR7 while exhibiting weak activity at mGluR5 and mGluR8 VU 0361737 crosses the blood-brain barrier and achieves significant brain exposure (brain plasma ratio of 4 1) with a short half-life (T1/2 20 min) following administration in rats This compound is utilized in studies exploring the modulation of basal ganglia neurotransmission and the pathophysiology of Parkinson s disease
Medchemexpress LLC SB-224289 (hydrochloride) | 180084-26-8 | 99.0% | 557.08 g/mol | C32H33ClN4O3 | 100 MG
SB-224289 hydrochloride is a research-grade selective 5-HT1B receptor antagonist reported to have anxiolytic effects. Supplied as the hydrochloride salt in solid form, it is intended for laboratory research use only and is used in pharmacology and neuroscience studies of 5-HT1B receptor function.
- High purity: 99.0%.
- Cas number: 180084-26-8.
- Molecular formula C32H33ClN4O3; molecular weight 557.08 g/mol.
- Supplied as a 100 MG solid pack.
- Recommended storage under nitrogen at -20°C; in solution -80°C (6 months), -20°C (1 month).
- For research use only; not for human or clinical use.
Medchemexpress LLC Cp-100356 monohydrochloride | 142715-48-8 | MFCD00911858 | >98.0% | 597.10 g·mol⁻¹ | C31H37ClN4O6 | 1 ML
CP-100356 hydrochloride is a research-grade inhibitor of multidrug transporters used to study transporter-mediated drug disposition and drug-drug interactions. It is supplied in both solid form and as a ready-to-use 10 mM solution in DMSO for in vitro assays, and it is commonly used in pharmacokinetic and cellular uptake studies.
- Potent inhibitor of P-gp and BCRP transporters.
- Available as a 10 mM solution in DMSO or as solid packs (5-100 mg).
- High purity suitable for in vitro assays (>98% by HPLC).
- Well characterized molecular properties for experimental reproducibility.
- Used for transporter assays and drug-drug interaction studies.
eMolecules 1069115-10-1 | 4-PYRIDINEACETIC ACID, 3-BROMO-ALPHA,ALPHA-DIMETHYL-, ETHYL ESTER | AstaTech | MFCD25372692 | 272.142 | C11H14BrNO2 | 95.000 | CCOC(=O)C(C)(C)c1ccncc1Br | 0.25g | 434268991
4-PYRIDINEACETIC ACID, 3-BROMO-ALPHA,ALPHA-DIMETHYL-, ETHYL ESTER | AstaTech | 1069115-10-1 | MFCD25372692 | 272.142 | C11H14BrNO2 | 95.000 | CCOC(=O)C(C)(C)c1ccncc1Br | 0.25g | 434268991