Hydrochlorides
Medchemexpress LLC LY2389575 hydrochlor 5mg | 885104-09-6 | 5MG
LY2389575 hydrochloride is a selective and noncompetitive mGlu3 negative allosteric modulator (NAM) with an IC50 value of 190 nM LY2389575 hydrochloride induces an increase in Mrc1 levels LY2389575 hydrochloride also independently amplifies Amyloid beta (A ) toxicity and can be used in study of Alzheimer s disease[1 [2 [3
Medchemexpress LLC TC-A 2317 hydrochloride | 1245907-03-2 | MFCD19690936 | >=98.0% | 392.93 | C19H29ClN6O | 1 MG
TC-A 2317 hydrochloride is the hydrochloride salt of TC-A 2317, a small-molecule Aurora kinase inhibitor used in cell-cycle and DNA damage research. It is supplied as a research reagent for biochemical and cellular studies.
- Used in cell-cycle and DNA damage pathway studies.
- Hydrochloride salt form for improved stability and solubility.
- Molecular formula C19H29ClN6O; molecular weight 392.93.
- Available in small pack sizes suitable for screening and assay work.
- Store sealed at 4°C; in solvent, store at -80°C up to 6 months or -20°C up to 1 month.
Chemscene ChemScene | 5-Bromo-3-pyridylacetic acid | 5G | CS-W014873 | 0.96 | 39891-12-8| MFCD00829308 | 216.034
ChemScene | 5-Bromo-3-pyridylacetic acid | 5G | CS-W014873 | 0.96 | 39891-12-8| MFCD00829308 | 216.034
Medchemexpress LLC Zacopride hydrochloride | 101303-98-4 | MFCD04971977 | 99.7% | 346.25 | C15H21Cl2N3O2 | 1 ML
Zacopride hydrochloride is a research-grade 5-HT3 receptor antagonist supplied as either a 10 mM solution in DMSO or as solid material for pharmacological and analytical studies. It has defined purity and physicochemical properties suitable for in vitro and in vivo protocols. Intended for research use only.
- High purity (99.69%).
- Concentration: 10 mM solution, 1 mL vial in DMSO.
- Also available as solid in multiple masses (5-100 mg; larger sizes by quote).
- Molecular weight 346.25; formula C15H21Cl2N3O2.
- CAS number 101303-98-4.
- Recommended solvent: DMSO; in vivo formulation suggestions provided.
- For research use only; not for human or clinical use.
Chemscene ChemScene | 2-Iminothiolane (hydrochloride) | 1G | CS-W016514 | 0.98 | 4781-83-3| MFCD00039013 | 137.63
ChemScene | 2-Iminothiolane (hydrochloride) | 1G | CS-W016514 | 0.98 | 4781-83-3| MFCD00039013 | 137.63
FUJIFILM BIOSCIENCES INC 2 5-DIAMINOTOLUENE DIHYDROCHLO
*Orders for this supplier are non-cancellable/non-returnable once they are processed.* 2,5-Diaminotoluene Dihydrochloride 250GR
Medchemexpress LLC VU-1545 | 890764-63-3 | 99.0% | 402.38 | 50 MG
VU-1545 is a metabotropic glutamate receptor 5 positive allosteric modulator (mGluR5 PAM). It exhibits a Ki of 156 nM and an EC50 of 9.6 nM. This compound promotes AKT activation at concentrations of 0.1 and 1.0 μM and is intended for research use only.
- Functions as a metabotropic glutamate receptor 5 positive allosteric modulator (mGluR5 PAM).
- Demonstrates a Ki of 156 nM and an EC50 of 9.6 nM.
- Promotes AKT activation.
- Promotes Akt phosphorylation in neuronal cells.
- Solid appearance, light yellow to yellow color.
- Powder storage: -20°C for 3 years, 4°C for 2 years.
- In solvent storage: -80°C for 6 months, -20°C for 1 month.
Medchemexpress LLC 5,7-dimethoxy-3-(4-pyridinyl)quinoline dihydrochloride | 1123491-15-5 | MFCD02262123 | 99.1% | 339.22 g/mol | C16H16Cl2N2O2 | 5 MG
DMPQ dihydrochloride is the dihydrochloride salt of 5,7-dimethoxy-3-(4-pyridinyl)quinoline. It is a small-molecule inhibitor that selectively targets human platelet-derived growth factor receptor β (PDGFRβ) with reported biochemical potency, and is supplied as a light yellow to yellow solid for research use in biochemical and cell-based assays.
- Potent PDGFRβ inhibition with reported IC50 of 80 nM.
- High reported purity suitable for biochemical assays.
- Solid form, convenient for weighing and formulation.
- Available in multiple small pack sizes for research applications.
Sigma Aldrich Fine Chemicals Biosciences o-Phenylenediamine dihydrochloride tablet, 60 mg substrate per tablet | 615-28-1 | MFCD00012966 | 50TAB
o-Phenylenediamine dihydrochloride tablet, 60 mg substrate per tablet | Mol Wt: 181.06 | 615-28-1 | MFCD00012966 | 50TAB
![Medchemexpress LLC 6-(4-(4-methylthiazol-2-yl)-1H-imidazol-5-yl)benzo[d]thiazole hydrochloride | 2459963-17-6 | MFCD32633583 | 99.2% | 334.85 g/mol | C14H11ClN4S2 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000308312.png-250.jpg)
Medchemexpress LLC 6-(4-(4-methylthiazol-2-yl)-1H-imidazol-5-yl)benzo[d]thiazole hydrochloride | 2459963-17-6 | MFCD32633583 | 99.2% | 334.85 g/mol | C14H11ClN4S2 | 10 MG
TP0427736 hydrochloride is a research-grade small-molecule ALK5 (TGF-β receptor I) inhibitor supplied as the hydrochloride salt. The compound is provided as a high-purity solid intended for in vitro biochemical and cellular studies, with documented solubility in water and DMSO and recommended cold storage for long-term stability.
- High purity suitable for research assays.
- Hydrochloride salt form improves aqueous and DMSO solubility.
- Documented solubility values aid experimental planning.
- Stable when stored as powder at recommended cold temperatures.
- Appropriate for pathway, target validation, and pharmacology studies.
Medchemexpress LLC L-778123 hydrochloride | 253863-00-2 | 99.9% | 442.34 | 1 ML
L-778123 hydrochloride is a dual inhibitor of FPTase and GGPTase-I, with IC50 values of 2 nM and 98 nM respectively. For research use only, not for sale to patients. In vitro, it does not show obvious cytotoxicity on HT-29 and A549 cell lines (IC50: >100 μM) but can generate synergistic effects with Doxorubicin, with decreased IC50s of 1.72 and 1.52 μM respectively. It inhibits myeloid leukemia cell proliferation with IC50 values of 0.2 μM-1.8 μM for cell lines, and 0.1 μM-161.8 μM in primary samples. It inhibits H-RAS prenylation in HL-60 cells, and inhibits phosphorylated MEK-1/2 level. It also inhibits lymphocyte activation and function in human PBMCs.
- Dual inhibitor of FPTase and GGPTase-I
- Shows synergistic effects with Doxorubicin
- Inhibits myeloid leukemia cell proliferation
- Inhibits H-RAS prenylation and phosphorylated MEK-1/2 level
- Inhibits lymphocyte activation and function
Medchemexpress LLC L-778123 hydrochloride | 253863-00-2 | 99.9% | 442.34 | 50 MG
L-778123 hydrochloride is a dual inhibitor of FPTase and GGPTase-I, with IC50 values of 2 nM and 98 nM respectively. It is intended for research use only.
- Dual inhibitor of FPTase and GGPTase-I.
- Exhibits IC50 values of 2 nM for FPTase and 98 nM for GGPTase-I.
- Alone, it does not show obvious cytotoxicity on HT-29 and A549 cell lines (IC50: >100 μM), but can generate synergistic effects with Doxorubicin.
- Inhibits myeloid leukemia cell proliferation with IC50 values ranging from 0.2 μM to 1.8 μM for cell lines, and 0.1 μM to 161.8 μM in primary samples.
- Inhibits H-RAS prenylation in HL-60 cells and phosphorylated MEK-1/2 levels.
- Inhibits lymphocyte activation and function in human PBMCs.
Medchemexpress LLC Co 101244 hydrochloride | 193356-17-1 | 99.9% | 377.90 | C21H28ClNO3 | 10 MG
Co 101244 hydrochloride (PD 174494 hydrochloride) is a selective antagonist of NR2B (GluN2B)-containing NMDA receptors used to study NMDA receptor pharmacology and neuronal signaling in vitro. The hydrochloride salt is characterized by formula C21H28ClNO3, molecular weight 377.90 g/mol, and supplier-reported purity near 99.9%. It is supplied in small-molecule formats for research assays.
- Selective antagonist of NR2B-containing NMDA receptors.
- High chemical purity for reproducible experimental results.
- Hydrochloride salt form for improved solubility in assay solvents.
- Suitable for in vitro pharmacology and receptor binding assays.
- Available in mg-scale solid and DMSO solution formats.
- Molecular weight and formula provided for dosing calculations.