Hydrochlorides
Medchemexpress LLC Iptakalim hydrochloride | 642407-63-4 | 98.0% | 179.73 g/mol | C9H22ClN | 10 MG
Iptakalim hydrochloride is a lipophilic para-amino small molecule used in research as an ATP-sensitive potassium (KATP) channel opener and α4β2-containing nicotinic acetylcholine receptor modulator. It is supplied as the hydrochloride salt for laboratory pharmacology and formulation studies.
- Acts as an ATP-sensitive potassium (KATP) channel opener and α4β2-containing nicotinic receptor modulator.
- CAS number 642407-63-4.
- Molecular formula C9H22ClN; molecular weight 179.73 g/mol.
- Purity 98.0%.
- Available in milligram pack sizes for research, including 10 mg.
- Solubility: water 25 mg/mL (requires warming and sonication); PBS formulations achievable.
- Storage: solid sealed at 4°C; in solution store at -80°C for long-term stability.
Medchemexpress LLC (±)-Bepridil hydrochloride hydrate | 74764-40-2 | 99.9% | 421.02 | 25 MG
Bepridil hydrochloride hydrate is a non-selective, long-acting calcium channel antagonist and sodium, potassium channel inhibitor. It exhibits antianginal and type I antiarrhythmic effects, and also functions as a cardiac Na+/Ca2+ exchange (NCX1) inhibitor. This product is intended for research on cardiovascular disorders.
- Non-selective calcium channel antagonist
- Long-acting
- Sodium channel inhibitor
- Potassium channel inhibitor
- Antianginal effects
- Type I antiarrhythmic effects
- Cardiac Na+/Ca2+ exchange (NCX1) inhibitor
- Blockades of Ca2+-dependent action potentials in vascular smooth muscle
- Blocks Ca currents and Na currents
- Decreases IKs under blockade of IKr
- Exhibits a half-life of averages 33±15 hours after single-dose administration
Medchemexpress LLC Vu0134992 hydrochloride | 1052515-91-9 | 98.5% | 1 ML
VU0134992 hydrochloride is a selective Kir4.1 inward-rectifier potassium channel blocker provided as the hydrochloride salt. Supplied as a 10 mM solution in DMSO or as a solid, it is used as a research tool to inhibit Kir4.1-mediated currents in electrophysiology and cell-based assays.
- Selective Kir4.1 blocker (IC50 = 0.97 μM).
- Supplied as hydrochloride salt for improved solubility.
- Available as 10 mM solution in DMSO or in solid form.
- Suitable for electrophysiology and cell-based assays.
- High purity suitable for research applications.
Medchemexpress LLC Doxapram hydrochloride hydrate | 7081-53-0 | MFCD09954698 | 99.3% | 432.98 g/mol | C24H33ClN2O3 | 10 MG
Doxapram hydrochloride hydrate is a small-molecule respiratory stimulant and TASK-1 potassium channel inhibitor supplied as a solid hydrate for research use. It is provided with high purity and is available in small solid quantities and pre-made DMSO solutions for assay work.
- High purity (99.3%).
- Molecular weight 432.98 g/mol.
- Supplied as a solid hydrate; white to off-white appearance.
- Available in small pack sizes suitable for assay development.
- Offered in solution formats (10 mM in DMSO) for immediate use.
Medchemexpress LLC Doxapram (hydrochloride hydrate) | 7081-53-0 | 99.3% | 1 ML
Doxapram hydrochloride hydrate is a respiratory stimulant that increases breathing rate and depth by acting on the brain's respiratory centers and peripheral chemoreceptors. It can be used for the study of respiratory depression such as post-anesthesia respiratory depression, chronic obstructive pulmonary disease, and apnea of prematurity.
- Inhibits TASK-1, TASK-3, and TASK-1/TASK-3 heterodimeric channel function
- Inhibits Ca²⁺-activated and Ca²⁺-independent potassium current in type I cells of the carotid body
- Significantly prolongs the effective refractory period of the atrium
- Has an anti-arrhythmic effect