Organic lithium salts
![Medchemexpress LLC Cholan-24-oic acid, 3-[(2S)-2-amino-3-carboxy-1-oxopropoxy]-, (3α,5β)- | 881179-02-8 | 98.0% | 491.66 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000436435-Logo.png-250.jpg){kind=logo}
Medchemexpress LLC Cholan-24-oic acid, 3-[(2S)-2-amino-3-carboxy-1-oxopropoxy]-, (3α,5β)- | 881179-02-8 | 98.0% | 491.66 | 50 MG
Lith-O-Asp is a sialyltransferase (ST) inhibitor with IC50s ranging from 12-37 μM. It has been shown to decrease the activity of both a-2,3- and a-2,6-sialyltransferases, inhibiting the transfer of sialic acids to targeted glycoproteins. Research indicates that Lith-O-Asp can suppress FAK/paxillin signaling, as well as cancer angiogenesis and metastasis pathways. It has demonstrated an ability to reduce lung metastases in animal models.
- Sialyltransferase (ST) inhibitor
- IC50s of 12-37 μM
- Suppresses FAK/paxillin signaling
- Inhibits cancer angiogenesis and metastasis pathways
- Decreases activity of a-2,3- and a-2,6-sialyltransferases
- Inhibits transfer of sialic acids to targeted glycoproteins
- Reduces lung metastases in vivo
![Medchemexpress LLC Cholan-24-oic acid, 3-[(2S)-2-amino-3-carboxy-1-oxopropoxy]-, (3α,5β)- | 881179-02-8 | 98.0% | 491.66 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000436434-Logo.png-250.jpg){kind=logo}
Medchemexpress LLC Cholan-24-oic acid, 3-[(2S)-2-amino-3-carboxy-1-oxopropoxy]-, (3α,5β)- | 881179-02-8 | 98.0% | 491.66 | 10 MG
Lith-O-Asp is a sialyltransferase (ST) inhibitor with IC50 values ranging from 12-37 μM. It has been shown to decrease the activity of both α-2,3- and α-2,6-sialyltransferases, thereby inhibiting the transfer of sialic acids to targeted glycoproteins. Research indicates that Lith-O-Asp may suppress cancer angiogenesis and metastasis pathways, as demonstrated by fewer lung metastases in treated mice compared to controls.
- Sialyltransferase (ST) inhibitor.
- Inhibits the activities of ST3Gal I, ST3Gal III, and ST6GalI.
- Decreases expression of cell surface α-2,3- and α-2,6-sialylated antigens.
- Suppresses cancer angiogenesis and metastasis pathways.
O | 1g | 482922328](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000225125.jpg-250.jpg)
eMolecules 3976-69-0 | Methyl (R)-3-hydroxybutyrate | Chemodex Ltd. | MFCD00063289 | 118.132 | C5H10O3 | 99.000 | COC(=O)C[C@@H](C)O | 1g | 482922328
Methyl (R)-3-hydroxybutyrate | Chemodex Ltd. | 3976-69-0 | MFCD00063289 | 118.132 | C5H10O3 | 99.000 | COC(=O)C[C@@H](C)O | 1g | 482922328
![Medchemexpress LLC Cholan-24-oic acid, 3-[(2S)-2-amino-3-carboxy-1-oxopropoxy]-, (3α,5β)- | 881179-02-8 | 98.0% | 491.66 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000440076-Logo.png-250.jpg){kind=logo}
Medchemexpress LLC Cholan-24-oic acid, 3-[(2S)-2-amino-3-carboxy-1-oxopropoxy]-, (3α,5β)- | 881179-02-8 | 98.0% | 491.66 | 25 MG
Lith-O-Asp is a sialyltransferase (ST) inhibitor, with IC50 values ranging from 12-37 μM against ST3Gal I, ST3Gal III, and ST6GalI. It inhibits α-2,3- and α-2,6-sialyltransferases, decreasing sialic acid transfer to targeted glycoproteins. Research shows potential in suppressing cancer angiogenesis and metastasis, with treated mice exhibiting fewer lung metastases in a 4T1-Luc breast cancer model.
- Sialyltransferase (ST) inhibitor
- IC50 values of 12-37 μM against ST3Gal I, ST3Gal III, and ST6GalI
- No apparent growth inhibition effect on different cancer cell lines at tested doses (10, 30, and 60 μM)
- Decreases expression of cell surface α-2,3- and α-2,6-sialylated antigens
- Suppresses FAK/paxillin signaling and cancer angiogenesis and metastasis pathways in vivo
Sigma Aldrich Fine Chemicals Biosciences SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES
NC3904204 TERT-BUTYLLITHIUM SOLUTI 100ML
Sigma Aldrich Fine Chemicals Biosciences Lithium acetate dihydrate1KG
Lithium acetate dihydrate is one of the commercially available forms of lithium acetate. Lithium acetate is a common salt with variety of applications such as product for efficient yeast transformation drug formulation and therapy lithium-6 CP/MAS standard solvent and catalyst. In addition it is also used as a buffer for gel electrophoresis of DNA and RNA additive or catalyst for textiles and polymer production and as a precursor material for batteries and ferromagnetic nanoparticles.
AdipoGen Bis(trifluoromethane)sulfonimide lithium salt
Bis(trifluoromethane)sulfonimide lithium salt, AdipoGen Life Sciences. Chemical. CAS: 90076-65-6. Formula: C2F6LiNO4S2. MW: 287.09. Synthetic Used in the preparation of electrolyte suitable for lithium batteries showing very high conductivity. Used in the preparation of a chiral imidazolium salt via anion metathesis of the corresponding triflate.
TARGETMOL CHEMICALS INC COLUMBIN 50MG
Also available in 5 mg 10 mg 25 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 1. Columbin has anti-inflammatory activity. 2. Columbin has chemopreventive ability against human colon cancer. 3. Columbin inhibits PLA2 hydrolysis of ghost RBC in a dose-dependent fashion. purity: 99%
Medchemexpress LLC Lithium acetate dihy 1kg
Lithium acetate dihydrate is a compound with a one-dimensional structure that has various applications in industries such as pharmaceuticals ceramics and research laboratories Lithium acetate dihydrate is often used as a source of lithium ions in chemical reactions and as a precursor in the synthesis of other lithium compounds[1]
Medchemexpress LLC Lith-O-Asp | 881179-02-8 | 98.0% | 491.66 | 100 MG
Lith-O-Asp is a sialyltransferase (ST) inhibitor with IC50s of 12-37 μM. It inhibits the activities of ST3Gal I, ST3Gal III, and ST6GalI, decreasing the expression of cell surface α-2,3- and α-2,6-sialylated antigens.
- Inhibits sialyltransferase (ST) activities with IC50 values ranging from 12 to 37 μM.
- Decreases the activity of both α-2,3- and α-2,6-sialyltransferases.
- Inhibits the transfer of sialic acids to targeted glycoproteins.
- Shows no apparent growth inhibition effect toward different cancer cell lines at tested doses.
- Leads to fewer lung metastases in treated mice.
- Decreases average tumor nodules per mouse in vivo.