Organophosphorus compounds

Medchemexpress LLC 1-(3,5-dimethylphenyl)-3-(2-(trifluoromethyl)phenyl)guanidine | 1430208-73-3 | MFCD31619254 | 99.7% | 307.31 | C16H16F3N3 | 100 MG

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A small-molecule Rac1 inhibitor that prevents EGF-induced Rac1 activation and disrupts Rac1-P-Rex1 interaction. It induces apoptosis and inhibits cell proliferation, migration, and cell-cycle progression in a concentration-dependent manner, and has demonstrated antimetastatic activity in vivo. Supplied as a white to off-white solid, it is intended for research applications.

• Inhibits Rac1 activation and Rac1-P-Rex1 interaction.
• Induces apoptosis and inhibits cell proliferation, migration, and cell-cycle progression.
• Demonstrates antimetastatic activity in vivo.
• Supplied as a white to off-white solid and as a DMSO solution.
• High purity suitable for research applications.
• Compatible with in vitro and in vivo assays for Rac1 pathway studies.

Medchemexpress LLC N-(3,5-dimethylphenyl)-N'-[2-(trifluoromethyl)phenyl]-guanidine | 1430208-73-3 | MFCD31619254 | 99.7% | 307.31 | C16H16F3N3 | 1 ML

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1A-116 is a small-molecule Rac1 inhibitor used in biological research to block Rac1 activation and downstream signaling. It disrupts Rac1-P-Rex1 interaction, induces apoptosis, and inhibits cell proliferation, migration, and cell cycle progression, and has shown antimetastatic activity in vivo.

• Potent Rac1 inhibitor that blocks Rac1-P-Rex1 interaction.
• Induces apoptosis and inhibits cell proliferation, migration, and cell cycle progression.
• Demonstrated antimetastatic activity in vivo.
• Available as a 10 mM solution in DMSO (1 mL) and in solid formats.
• High purity, 99.7%.
• Molecular weight 307.31 g/mol and formula C16H16F3N3.
• Recommended storage: powder at -20°C; in solvent at -80°C for long-term storage.

Medchemexpress LLC 1-(3,5-dimethylphenyl)-2-[2-(trifluoromethyl)phenyl]guanidine | 1430208-73-3 | 99.7% | 307.31 g·mol⁻¹ | C16H16F3N3 | 25 MG

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1A-116 is a small-molecule Rac1 inhibitor that selectively targets the W56 residue to prevent EGF-induced Rac1 activation and disrupt Rac1-P-Rex1 interaction. It induces apoptosis and inhibits cell proliferation, migration, and cell-cycle progression in a concentration-dependent manner, and has demonstrated antimetastatic activity in vivo. Molecular formula C16H16F3N3; molecular weight 307.31 g·mol⁻¹; reported purity 99.72%.

• Selective Rac1 inhibition via W56 targeting.
• Prevents EGF-induced Rac1 activation.
• Blocks Rac1-P-Rex1 interaction.
• Induces apoptosis and inhibits cell proliferation and migration.
• Demonstrates antimetastatic activity in vivo.

Medchemexpress LLC 1-(3,5-dimethylphenyl)-2-[2-(trifluoromethyl)phenyl]guanidine | 1430208-73-3 | MFCD31619254 | 99.7% | 307.31 g·mol⁻¹ | C16H16F3N3 | 50 MG

Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
Learn More

1A-116 is a small-molecule Rac1 inhibitor for research use that blocks Rac1 activation and disrupts Rac1-P-Rex1 interaction. It prevents EGF-induced Rac1 activation and has been shown to induce apoptosis in a circadian-dependent manner. Supplied as a white to off-white solid, the compound has a molecular weight of 307.31 g·mol⁻¹ and high purity (~99.7%), appropriate for biochemical and cell-based studies.

• Blocks Rac1 activation and Rac1-P-Rex1 interaction.
• Prevents EGF-induced Rac1 activation in cell assays.
• Induces apoptosis in a circadian-dependent manner in studied models.
• High purity suitable for biochemical and cell-based experiments.
• Available in multiple small-scale packaging options for laboratory research.
• Stable as a powder under recommended storage conditions.