Metal Aryls
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eMolecules Ambeed Methyl 3-amino-5 6-dichloro-2-pyrazinecarboxylate 50mg 521393976 A108171 0 000 1458-18-0 MFCD00010431 222 030 C6H5Cl2N3O2
Ambeed Methyl 3-amino-5 6-dichloro-2-pyrazinecarboxylate 50mg 521393976 A108171 0 000 1458-18-0 MFCD00010431 222 030 C6H5Cl2N3O2
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Medchemexpress LLC ABT-639 | 1235560-28-7 | 99.3% | 455.91 | 5 MG
ABT-639 is a novel, peripherally acting, selective T-type Ca2+ channel blocker. It is for research use only and not sold to patients.
- Novel, peripherally acting, selective T-type Ca2+ channel blocker.
- Blocks recombinant human T-type (Cav3.2) Ca2+ channels (IC50=2 μM).
- Attenuates low voltage-activated (LVA) currents in rat DRG neurons (IC50=8 μM).
- Less active at other Ca2+ channels (e.g., Cav1.2, Cav2.2) (IC50>30 mM).
- High oral bioavailability (%F=73), low protein binding (88.9%), low brain:plasma ratio (0.05:1) in rodents.
- Produces dose-dependent antinociception in rat model of knee joint pain (ED50=2 mg/kg, p.o.).
- Increases tactile allodynia thresholds in multiple models of neuropathic pain (10-100 mg/kg, p.o.).
- Does not attenuate hyperalgesia in inflammatory pain models.
- Does not significantly alter hemodynamic or psychomotor function at higher doses (e.g., 100-300 mg/kg).
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eMolecules 131747-43-8 | 2-(Trifluoromethyl)pyridine-3-carboxylic Acid | Accela ChemBio (ASD) | MFCD01862052 | 191.109 | C7H4F3NO2 | 97.000 | OC(=O)c1cccnc1C(F)(F)F | 1g | 444758920
2-(Trifluoromethyl)pyridine-3-carboxylic Acid | Accela ChemBio (ASD) | 131747-43-8 | MFCD01862052 | 191.109 | C7H4F3NO2 | 97.000 | OC(=O)c1cccnc1C(F)(F)F | 1g | 444758920
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Frontier Specialty Chemicals 100G 2-(TRIBUTYLSTANNYL)PYRIDI
100g 2-(tributylstannyl)pyridi. 17997-47-6
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Aobchem Methyl 4-(benzyloxy)-3 5-dichlorobenzoate | ≥97% | CAS 536974-83-1 | C15H12Cl2O3 | 500mg
Methyl 4-(benzyloxy)-3 5-dichlorobenzoate | ≥97% | CAS 536974-83-1 | C15H12Cl2O3 | 500mg
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