Organo-Metalloid Compounds
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Filtered Search Results
Medchemexpress LLC Azide-PEG3-Desthiobi 25mg
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Azide-PEG3-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1] Azide-PEG3-Desthiobiotin is a click chemistry reagent it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
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eMolecules Azido-PEG5-triethoxysilane | Broadpharm |538.714 | C22H46N4O9Si | 98.000 | CCO[Si](CCCNC(=O)CCOCCOCCOCCOCCOCCN=[N+]=[N-])(OCC)OCC | 1g | 411413987
Azido-PEG5-triethoxysilane | Broadpharm |538.714 | C22H46N4O9Si | 98.000 | CCO[Si](CCCNC(=O)CCOCCOCCOCCOCCOCCN=[N+]=[N-])(OCC)OCC | 1g | 411413987
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Medchemexpress LLC [2-[[5-[(4-fluorophenyl)carbamoyl]pyrimidin-2-yl]sulfanylmethyl]-4-(trifluoromethoxy)phenyl]boronic acid | 1648843-04-2 | 98.7% | 1 ML
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SX-682 is a small-molecule allosteric inhibitor of chemokine receptors CXCR1 and CXCR2. It has been investigated preclinically and in clinical trials for reducing tumor myeloid-derived suppressor cell recruitment and enhancing anti-tumor immune responses.
- Potent CXCR1/2 allosteric inhibitor used in research.
- Investigated in immuno-oncology and tumor microenvironment studies.
- Reported to reduce myeloid-derived suppressor cell recruitment.
- Supplied for laboratory research, often as concentrated solutions or milligram-scale powders.
- Soluble in DMSO at high concentrations for in vitro use.
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Medchemexpress LLC M-PEG3-SH | 31521-83-2 | 98.95% | 180.27 | 10 G
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m-PEG3-SH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are molecules designed to degrade target proteins by leveraging the intracellular ubiquitin-proteasome system.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Designed to selectively degrade target proteins
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eMolecules 31127-85-2 | HOOCCH2CH2O-PEG3-CH2CH2COOH | Acrotein ChemBio Inc. | MFCD22201545 | 294.300 | C12H22O8 | 97.000 | OC(=O)CCOCCOCCOCCOCCC(O)=O | 5g | 487537379
HOOCCH2CH2O-PEG3-CH2CH2COOH | Acrotein ChemBio Inc. | 31127-85-2 | MFCD22201545 | 294.300 | C12H22O8 | 97.000 | OC(=O)CCOCCOCCOCCOCCC(O)=O | 5g | 487537379
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eMolecules 867062-95-1 | Fmoc-NH-PEG3-CH2CH2COOH | ChemScene | MFCD06656471 | 443.496 | C24H29NO7 | 96.000 | OC(=O)CCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 10g | 582640564
Fmoc-NH-PEG3-CH2CH2COOH | ChemScene | 867062-95-1 | MFCD06656471 | 443.496 | C24H29NO7 | 96.000 | OC(=O)CCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 10g | 582640564
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Medchemexpress LLC HO-PEG3-(CH2)6-Cl | 1355955-95-1 | 95.0% | 268.78 | C12H25ClO4 | 5 MG
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HO-PEG3-(CH2)6-Cl is a PEG-based PROTAC linker containing a hydroxy-terminated PEG3 spacer attached to a six-carbon chain bearing a terminal chloride. It is intended as a functionalized spacer for assembling PROTACs and other ligand-linker conjugates and is supplied for research use only.
- Hydroxy-terminated PEG3 linker for flexible spacer design.
- Six-carbon chloroalkyl handle enables haloalkane conjugation chemistry.
- Suitable for assembling PROTACs and ligand-linker constructs.
- Available in small research-scale quantities, such as 5 mg.
- Molecular formula C12H25ClO4 and molecular weight 268.78.
- For research use only; not for human or clinical use.
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Medchemexpress LLC (S,R,S)-AHPC-C2-PEG3-BCN | 2876198-36-4 | 98.4% | 810.01 | 100 MG
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(S,R,S)-AHPC-C2-PEG3-BCN (Compound 16b) is a VHL ligand that can be used for the synthesis of PROTACs. It is intended for research use only and is not for sale to patients. Its appearance is a solid, ranging from white to light yellow in color.
- VHL ligand
- Can be used for the synthesis of PROTACs
- Intended for research use only
- Solid, white to light yellow appearance
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Medchemexpress LLC Perfluorophenyl 3-(2-(2-(2-(1,3-dioxoisoindolin-2-yloxy)ethoxy)ethoxy)ethoxy)propanoate | 2101206-87-3 | >96.0% | 533.4 g/mol | C23H20F5NO8 | 10 MG
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NHPI-PEG3-C2-Pfp ester is a noncleavable, trifunctional 3-unit polyethylene glycol (PEG) linker bearing an N-hydroxyphthalimide (NHPI) group and a perfluorophenyl (Pfp) activated ester. It is used for bioconjugation and in the synthesis of antibody-drug conjugates (ADCs). Intended for research use only.
- Noncleavable 3-unit PEG linker
- NHPI functional group for site-specific conjugation
- Perfluorophenyl activated ester for amine coupling
- Molecular weight about 533.4 g/mol; formula C23H20F5NO8
- Purity greater than 96%
- Intended for research use only, not for human or animal use
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Medchemexpress LLC N-Boc-C1-PEG3-C3-NH2 | 194920-62-2 | 320.42 | 25 G
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N-Boc-C1-PEG3-C3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Connects two ligands in PROTACs
- Facilitates protein degradation via ubiquitin-proteasome system
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Tos-PEG3-CH2COOtBu | 1530778-24-5 | 418.50 | 10 G
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Tos-PEG3-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Contains two different ligands connected by a linker
- Ligands for an E3 ubiquitin ligase and a target protein
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eMolecules 134179-38-7 | Amino-PEG3-C2-Azido | Medchem Express | MFCD00269874 | 218.257 | C8H18N4O3 | 98.000 | NCCOCCOCCOCCN=[N+]=[N-] | 500mg | 746319562
Amino-PEG3-C2-Azido | Medchem Express | 134179-38-7 | MFCD00269874 | 218.257 | C8H18N4O3 | 98.000 | NCCOCCOCCOCCN=[N+]=[N-] | 500mg | 746319562
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Medchemexpress LLC Azido-PEG3-SSPy | 98.6% | 344.45 g/mol | C13H20N4O3S2 | 25 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Azido-PEG3-SSPy is a cleavable three-unit polyethylene glycol (PEG) linker containing an azide functional group, designed for bioconjugation and antibody-drug conjugate (ADC) synthesis. It enables click chemistry (CuAAC) and strain-promoted azide-alkyne cycloadditions (SPAAC) for attachment to alkyne- or DBCO/BCN-containing molecules.
- Cleavable disulfide-containing PEG linker suitable for ADC construction.
- Azide-functionalized for copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Compatible with strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN.
- Supplied as a colorless to light yellow liquid with high purity.
- Suitable for bioconjugation and linker development in drug conjugates.
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eMolecules 252881-74-6 | NH2-PEG3-C2-Boc | Ambeed | MFCD06201017 | 277.361 | C13H27NO5 | 97.000 | CC(C)(C)OC(=O)CCOCCOCCOCCN | 5g | 526391552
NH2-PEG3-C2-Boc | Ambeed | 252881-74-6 | MFCD06201017 | 277.361 | C13H27NO5 | 97.000 | CC(C)(C)OC(=O)CCOCCOCCOCCN | 5g | 526391552
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Medchemexpress LLC 4,7,10,13-tetraoxatetradecanoic acid | 67319-28-2 | 97.0% | 236.26 | C10H20O6 | 1 G
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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m-PEG3-CH2CH2COOH is a monomethyl-terminated PEG3 linker bearing a terminal carboxylic acid, used as a non-cleavable linker in antibody-drug conjugate and PROTAC synthesis. It is supplied as a colorless to light yellow liquid with a high NMR purity and defined molecular properties.
- Monomethyl-terminated PEG3 linker
- Terminal carboxylic acid functionality for conjugation
- Suitable for ADC and PROTAC synthesis
- Colorless to light yellow liquid form
- 97.0% purity (NMR)
- Molecular weight 236.26; formula C10H20O6
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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