Heptane

Medchemexpress LLC Br102910 | 2505339-54-6 | MFCD34565708 | 99.8% | 459.30 | C18H14Cl2F2N4O2S | 100 MG

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BR102910 is a small-molecule research inhibitor of fibroblast activation protein (FAP) with reported nanomolar potency (IC50 2 nM). It is provided as a high-purity solid for in vitro and preclinical studies and shows additional activity against prolyl oligopeptidase (PREP).

• High potency FAP inhibitor (IC50 2 nM).
• Activity against PREP (IC50 49.0 μM) and minimal DPP-4 activity (>100 μM).
• Purity 99.82%.
• Molecular weight 459.30; formula C18H14Cl2F2N4O2S.
• Solid, white to off-white appearance; typical pack size 100 MG.
• Recommended storage: 4°C for solid; in solvent -80°C (6 months) or -20°C (1 month).
• Includes structural data (SMILES) for computational and modeling use.

Medchemexpress LLC BR102910 | 2505339-54-6 | MFCD34565708 | 99.8% | 459.30 | C18H14Cl2F2N4O2S | 50 MG

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A selective fibroblast activation protein (FAP) inhibitor for biochemical and cellular research. It exhibits potent FAP inhibition and weaker activity against prolyl oligopeptidase, making it useful for studies of FAP-related biology and metabolic disease models.

• Potent FAP inhibition (IC50 = 2 nM).
• Also inhibits prolyl oligopeptidase (IC50 = 49.0 μM).
• High purity (99.8%).
• Solid form, white to off-white powder.
• Molecular weight 459.30, formula C18H14Cl2F2N4O2S.
• CAS number 2505339-54-6 for unambiguous identification.
• Store solid at 4°C; in solvent store at -80°C (6 months) or -20°C (1 month).

Medchemexpress LLC 2-propenamide, 3-(3-chlorophenyl)-N-[2-[4-(methylsulfonyl)-1-piperazinyl]-2-oxoethyl]-, (2E)- | 2505001-54-5 | 100.0% | 385.87 g·mol-1 | C16H20ClN3O4S | 5 MG

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SR15006 is a small-molecule inhibitor of Krüppel-like factor 5 (KLF5) supplied as a high-purity research reagent. It has reported activity in cell-based assays (IC50 = 41.6 nM in DLD-1/pGL4.18hKLF5p cells) and is provided with solubility and storage guidance for in vitro and in vivo use.

• Inhibits KLF5 with IC50 = 41.6 nM in DLD-1/pGL4.18hKLF5p cells.
• High purity suitable for research applications.
• Soluble in DMSO at 100 mg/mL; example in vivo formulations provided.
• Recommended storage: solid at 4°C; in solution -80°C (6 months) or -20°C (1 month).
• Molecular formula C16H20ClN3O4S; molecular weight 385.87 g·mol-1.
• For research use only; not for human or clinical use.

Medchemexpress LLC N-(2-(2-acrylamidophenyl)-4-(pyridin-4-yl)thiazol-5-yl)-2-(difluoromethyl)benzamide | 2227368-54-7 | MFCD34593626 | 99.0% | 452.46 g/mol | C25H20N6O3 | 25 MG

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Potent and selective IRAK1 inhibitor for research use. The compound inhibits IRAK1 with an apparent IC50 of 9 nM and shows no inhibition of IRAK4 at concentrations up to 10 μM. Supplied as a solid or as a DMSO solution, it provides defined solubility and storage properties.

• Potent, selective IRAK1 inhibition with an apparent IC50 of 9 nM.
• High purity (99.03%) for reliable experimental results.
• Available as solid and as 10 mM solutions in DMSO for flexible dosing.
• Molecular weight 452.46 g/mol; molecular formula C25H20N6O3.
• High solubility in DMSO (125 mg/mL) and in vivo formulation solubility ≥1.98 mg/mL under protocol conditions.
• Stable storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).