Tetrahydrofuran
Medchemexpress LLC 5-(1-methyl-1H-pyrazol-4-yl)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)nicotinamide | 2095849-04-8 | MFCD31813597 | 98.0% | 479.45 g·mol⁻¹ | C25H20F3N5O2 | 5 MG
CSF1R-IN-1 is a potent small-molecule inhibitor of the colony-stimulating factor 1 receptor (CSF1R) with a reported IC50 of 0.5 nM. The compound demonstrates good intestinal permeability in Caco-2 assays and favorable oral pharmacokinetics in mice, supporting its use for in vivo pharmacology testing in preclinical tumor models.
- Potent CSF1R inhibition (IC50 = 0.5 nM).
- Good intestinal permeability in Caco-2 assays.
- Favorable oral pharmacokinetics in mice for in vivo studies.
- High purity suitable for research applications.
- Recommended storage as a powder at -20°C to maintain stability.
Medchemexpress LLC Dalpiciclib | 5MG
Dalpiciclib (SHR-6390) is an orally active and highly selective inhibitor of CDK4 and 6 with IC50 values of 12 4 nM and 9 9 nM respectively[1][2] Dalpiciclib shows antitumor activity against breast cancer and esophageal squamous cell carcinoma[1][2][3][4]
Medchemexpress LLC Phosphatidylinositols, soya, sodium salts | 383907-36-6 | MFCD00145109 | 99.3% | 857.0352 | C43H78NaO13P | 5 MG
Phosphatidylinositols, soya, sodium salts is a soy-derived mixture of phosphatidylinositol lipids provided as the sodium salt for research use. Phosphoinositides participate in membrane trafficking and lipid signaling by recruiting or activating effector proteins; this material is supplied as a solid for biochemical and lipid biology applications.
- High reported purity (99.3%).
- Supplied as a solid, white to off-white.
- Available in small vial sizes suitable for assay work.
- Suitable for studies of vesicular transport, membrane fusion, and cytoskeleton dynamics.
- Store sealed at -20°C; in solvent, -80°C recommended for long-term storage.
Medchemexpress LLC Zectivimod | 1623066-63-6 | 99.4% | 528.5 g/mol | C28H31Cl2N3O3 | 5 MG
Zectivimod is a small-molecule sphingosine-1-phosphate receptor (S1P1) agonist used in research on immune modulation. It has been investigated as an orally available S1P1 modulator and is employed in preclinical and clinical research focused on autoimmune and chronic inflammatory diseases. The compound is supplied for laboratory research use only.
- Selective S1P1 receptor agonist for immune modulation studies.
- Investigated as an orally available S1P1 modulator.
- Useful for research into autoimmune and chronic inflammatory diseases.
- High chemical purity (>99%).
- Supplied in small laboratory quantities for experimental use.
- Not for human or veterinary use; for research only.
Medchemexpress LLC GW406108X 50mg | 1644443-92-4 | 400.21 | C20H11Cl2NO4 | 50 MG
GW406108X (GW108X) is a small-molecule research inhibitor of Kif15 and ULK1 used in cellular and biochemical studies of mitosis and autophagy. It is supplied as a high-purity research chemical (CAS 1644443-92-4) with molecular formula C20H11Cl2NO4 and molecular weight 400.21.
- High purity (98.0%) suitable for biochemical and cellular assays.
- Reported activity against Kif15 and ULK1 for mechanistic studies.
- Known molecular weight and formula to support compound characterization.
- Supplied as a solid with good solubility in DMSO for stock preparation.
- Available in small pack sizes appropriate for research-scale experiments.
Medchemexpress LLC Taurohyodeoxycholic 50mg | 386523 | 50 MG
Taurohyodeoxycholic acid is a taurine-conjugated 6α-hydroxylated bile acid used in preclinical research to study liver disease, colitis, and biliary disorders. It exhibits anti-inflammatory effects, including reductions in MPO activity, TNF-α, and IL-6.
- Used to study nonalcoholic fatty liver disease and colitis.
- Shows anti-inflammatory activity in animal models.
- Available in multiple solid and solution pack sizes.
- Chemical formula C26H45NO6S; molecular weight 499.70 g/mol.
Medchemexpress LLC Nelonicline | 1026134-63-3 | 99.8% | 313.42 g/mol | C17H19N3OS | 10 MG
Nelonicline is an orally active, selective agonist of the α7 nicotinic acetylcholine receptor supplied as a research reagent for preclinical and in vitro studies. It has molecular formula C17H19N3OS and molecular weight 313.42 g/mol. For research use only; not for clinical or diagnostic applications.
- Selective α7 nicotinic acetylcholine receptor agonist suitable for receptor pharmacology studies.
- Orally active small molecule compatible with in vivo and in vitro experiments.
- Available as a 10 MG solid and as a 10 mM solution in DMSO for assay use.
- High-purity research compound appropriate for preclinical studies.
- Supplied for research use only, not intended for therapeutic use.