Acyl Halides
Apexbio Technology LLC Aclidinium Bromide 320345-99-1 50mg
Aclidinium Bromide (CAS 320345-99-1) is a long-acting muscarinic antagonist (LAMA) that selectively inhibits muscarinic acetylcholine receptors In binding assays it demonstrates high affinity for M1 M5 receptor subtypes with Ki values of 0 10 0 21 nM Functional studies reveal greater potency at endogenous M2 and M3 receptors with EC50 values of 17 4 nM and 5 3 nM respectively In vivo aclidinium bromide produces a concentration-dependent inhibition of acetylcholine-induced bronchoconstriction (EC50 2 5 23 1 g/mL in anesthetized guinea pigs) and suppresses pilocarpine-induced salivation in rats (EC50 38 g/kg) This compound is widely utilized in respiratory research for evaluating airway smooth muscle modulation via muscarinic receptor antagonism
Medchemexpress LLC 4-Benzoyl-3-methyl-1-phenyl-5-pyrazolone | 4551-69-3 | 99.9% | 278.31 | 1 G
4-Benzoyl-3-methyl-1-phenyl-5-pyrazolone is a heterocyclic compound featuring a five-membered ring structure. It serves as a versatile compound in scientific research.
- Can be used as a starting material for organic synthesis.
- Functions as a reagent for organic transformation.
- Acts as a biological probe for studying biological processes.
- Utilized as a biomaterial or organic compound for life sciences research.
AdipoGen 10-Octadecylacridine orange Br
Chemical. CAS 75168-16-0. Formula C35H56BrN3. MW 598.74. Synthetic. Fluorescent reagent with high selectivity. Potential sensitive dye PSD to monitor differences in cell potential as they occur during ion transport through the cell membrane.
Medchemexpress LLC KRN2 bromide | 1390654-28-0 | 98.8% | 524.38 | 1 ML
KRN2 (bromide) is a selective inhibitor of nuclear factor of activated T cells (NFAT5), with an IC50 of 0.1 μM. It is for research use only and not sold to patients.
- Selectively suppresses the expression of pro-inflammatory genes, including Nos2 and Il6.
- Dose-dependently inhibits the NF-κB p65 binding to Nfat5 promoter 1.
- Directly blocks the interaction between NF-κB p65 and its DNA binding sequence.
- Effectively suppresses AIA and CIA in mice.
- Decreases the production of pro-inflammatory cytokines and autoantibodies.
- Reduces macrophage infiltration.
Medchemexpress LLC N6-benzoyl-2'-deoxyadenosine monohydrate | 305808-19-9 | MFCD00149575 | 98.0% | 373.36 g/mol | C17H19N5O5 | 10 G
N6-benzoyl-2'-deoxyadenosine monohydrate is a protected nucleoside analog supplied as a monohydrate solid for research use. It serves as a building block in oligonucleotide and nucleotide chemistry and is characterized for purity and composition to support analytical and synthetic workflows.
- Protected adenosine derivative for nucleotide synthesis.
- Monohydrate solid, white to off-white in appearance.
- High purity (98.0%) for reproducible results.
- Available in multiple package sizes, including 10 G, for scale flexibility.
- Documented molecular weight and formula for formulation and analysis.
AdipoGen 4-ITCB-MPO-pyridinium bromide
Chemical. CAS 155862-90-1. Formula C23H18BrN3O2S. MW 480.38. Synthetic. New class of highly photostable, water soluble fluorescent labels with large Stokes shift, high QY in aqueous media and pH tolerance. Major disadvantage rel. low extinction coefficient.
Medchemexpress LLC Clidinium bromide | 3485-62-9 | 99.0% | 1 ML
Clidinium bromide is a quaternary amine antimuscarinic agent. It may help alleviate symptoms of cramping and abdominal/stomach pain by decreasing stomach acid and slowing the intestines in vivo. It is for research use only and not sold to patients.
- Quaternary amine antimuscarinic agent
- May decrease stomach acid
- May slow intestines in vivo
- Helps with cramping and abdominal/stomach pain symptoms