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Organic compounds that contain a carbon atom bonded to a halogen atom, and an oxygen atom via a double bond; commonly derived from an oxoacid by replacing a hydroxyl group with a halogen atom.
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
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1-Palmitoyl-2-linoleoyl-sn-glycero-3-PC (PLPC) is a phospholipid used as a major component in lipid bilayer system models. It can serve as an untreated control, mixed with oxidized lipids such as 1-palmitoyl-2-(13-hydroxy-9,11-octadecanedienoyl)-lecithin (OHPLPC) and 1-palmitoyl-2-(13-hydroperoxy-9,11-octadecanedienoyl)-lecithin (HpPLPC), to study the effects of oxidation on membrane properties.
Used as a major component in lipid bilayer system models.
Can serve as an untreated control to study the effects of oxidation on membrane properties when mixed with oxidized lipids.
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Also available in 1 mL, 1 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. 13-Methylberberine chloride shows anti-adipogenic effect on 3T3-L1 adipocytes, it has potential as an anti-obesity drug Purity 99.85%
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Also available in 1 mL, 1 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid exhibiting anti-inflammatory and anti-cancer activities and can enhance the activation of p38 MAPK. Purity 99.88%
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Hemin chloride (CAS 16009-13-5) is an oxidized derivative of heme known to inhibit eukaryotic translation initiation factor 2 kinase 1 (eIF2 K1) a negative regulator of eIF-2 EIF2 phosphorylation at Ser51 generally transforms eIF2 into an inhibitor of its guanine-nucleotide exchange factor eIF2 In biochemical assays Hemin chloride (20 40 M) reduces phosphorylation of eIF-2 and eIF-2 enhancing translation activity in cellular lysates Animal studies show hemin administration induces heme oxygenase-1 (HO-1) expression and delays thrombus formation in mice demonstrating its usefulness in translational regulation and vascular biology research
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Hemin chloride (CAS 16009-13-5) is an oxidized derivative of heme known to inhibit eukaryotic translation initiation factor 2 kinase 1 (eIF2 K1) a negative regulator of eIF-2 EIF2 phosphorylation at Ser51 generally transforms eIF2 into an inhibitor of its guanine-nucleotide exchange factor eIF2 In biochemical assays Hemin chloride (20 40 M) reduces phosphorylation of eIF-2 and eIF-2 enhancing translation activity in cellular lysates Animal studies show hemin administration induces heme oxygenase-1 (HO-1) expression and delays thrombus formation in mice demonstrating its usefulness in translational regulation and vascular biology research
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More