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Organic compounds that are derived from or have a benzene group in their molecular structure. Benzene is an aromatic organic molecule composed of 6 carbon atoms and 6 hydrogen atoms that form a ring. Includes derivatives and substituted molecules.
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(Rac)-Zevaquenabant is a high-purity research compound that acts as a cannabinoid receptor type 1 (CB1R) and inducible nitric oxide synthase (iNOS) antagonist, used for preclinical pharmacology and disease-model studies including liver fibrosis research. The compound is supplied as a powder with documented solubility and storage recommendations.
Dual CB1R and iNOS antagonist activity.
High reported CB1R affinity (Ki 5.7 nM).
High purity (99.2%).
Molecular weight 547.98 g/mol.
Soluble in DMSO; sonication recommended for stock solutions.
Stable when stored as powder at -20°C for long-term use.
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TNF-α-IN-2 is a small-molecule, orally active inhibitor of tumor necrosis factor alpha for research applications. It distorts the TNFα trimer to alter signaling and reduces E-selectin expression in cellular assays.
Potent TNFα inhibition with HTRF IC50 of 25 nM.
Inhibits E-selectin expression in HUVECs (IC50 30 nM).
High purity: 99.2%.
Solid, light yellow to yellow appearance.
Soluble in DMSO (100 mg/mL; may require sonication).
Stable as powder at -20 °C for long-term storage.
Available in multiple milligram pack sizes for research use only.
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GW-870086 is a synthetic glucocorticoid receptor agonist used in research to probe anti-inflammatory signaling. It inhibits NF-κB activity in A549 cells with a reported pIC50 of 10.1 and is supplied with high purity for in vitro pharmacology and cell-based assays.
Potent glucocorticoid receptor agonist active in cell-based NF-κB assays.
Reported pIC50 of 10.1 in A549 NF-κB assay.
High purity (99.59%) suitable for in vitro pharmacology.
Available as powder in multiple mg scales and as a 10 mM solution in DMSO for convenience.
Stable storage recommendations provided for powder and solvent solutions.
Molecular formula C31H39F2NO6; molecular weight 559.64.
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CCR2 antagonist 4 hydrochloride is a potent, selective CCR2 receptor antagonist supplied as the hydrochloride salt for biochemical and cell-based research. The compound shows activity against CCR2b and inhibits MCP-1-induced chemotaxis in cellular assays.
Hydrochloride salt suitable for research use.
Molecular formula C21H22Cl2F3N3O2; molecular weight 476.32 g/mol.
Purity 99.9% (as supplied).
Available in small research pack sizes, including 50 mg.
Reported CCR2b and chemotaxis inhibitory activity in cell-based assays.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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