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Organic compounds that consists entirely of hydrogen and carbon elements usually organized in a chain; some may have a cyclic structure. Includes hydrocarbons that have additional functional groups such as aromatic rings.
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2-Methylcyclopentane-1,3-dione is a chemical compound that serves as a key intermediate in the total synthesis of steroids. It is also utilized as a drug intermediate, and for general laboratory chemical applications including the manufacture of various substances.
Key intermediate for total synthesis of steroids
Drug intermediate
Suitable for laboratory chemical applications
Used in the manufacture of substances
White to light yellow solid appearance
High purity of 99.96% (HPLC)
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MD-224 is a first-in-class and highly potent small-molecule human murine double minute 2 (MDM2) degrader based on the proteolysistargeting chimera (PROTAC) concept MD-224 consists of ligands for Cereblon and MDM2 MD-224 induces rapid degradation of MDM2 at concentrations 1 nM in human leukemia cells and achieves an IC50 value of 1 5 nM in inhibition of growth of RS4 11 cells MD-224 has the potential to be a new class of anticancer agent[1] MD-224 is a click chemistry reagent it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups
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Octadecane-1-thiol-d37 is a deuterium labeled version of Octadecane-1-thiol. It is intended for research use only and not for sale to patients. Stable heavy isotopes like deuterium have been incorporated into drug molecules for use as tracers in drug development, and deuteration may impact the pharmacokinetic and metabolic profiles of drugs.
Used as a tracer.
Can be utilized as an internal standard for quantitative analysis through NMR, GC-MS, or LC-MS.
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NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT is a potent topoisomerase I inhibitor. It is designed for delivery to cells via conjugated antibody targeting, demonstrating strong antibody-drug conjugate (ADC) activity both in vivo and in vitro.
Functions as a topoisomerase I inhibitor
Designed for conjugated antibody targeting
Exhibits good ADC activity in vivo
Shows good ADC activity in vitro
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