Choose the brand aligned with your industry so we can best serve your needs.
For researchers, scientists, and technical professionals: Your one-stop shop for the complete range of laboratory, production, and safety products and services.
Organic compounds with acidic properties, and will commonly have carboxylic acids or similar functional groups in their structure. Derived compounds are also included.
Ixazomib Citrate (MLN9708) is a prodrug of Ixazomib (MLN2238) which is a selective orally bioavailable inhibitor of 20S proteasome that inhibits the chymotrypsin-like proteolytic ( 5) site with IC50 of 3 4 nM and Ki of 0 93 nM respectively Ixazomib (MLN2238) also inhibits caspase-like ( 1) and trypsin-like ( 2) proteolytic sites with IC50 of 31 nM and 3500 nM respectively
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
An inhibitor of FSP1; induces condensation and phase separation of FSP1 in cells at 2.5 µM; does not inhibit FSP1 enzymatic activity in a cell-free assay (IC50 = > 30 µM); induces ferroptosis in HT-1080 fibrosarcoma cells; decreases tumor volume and weight in a B16/F10 murine melanoma model using human FSP1-overexpressing, Gpx4-/-Fsp1-/- B16/F10 cells at 50 mg/kg
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More