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Trimethylamine oxide-15N is the deuterium labeled Trimethylamine N-oxide (HY-116084) Trimethylamine N-oxide is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients Trimethylamine N-oxide induces inflammation by activating the ROS/NLRP3 inflammasome Trimethylamine N-oxide also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF- /smad2 signaling pathway[1][2][3]
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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PSB-1114 triethylamine is a potent, enzymatically stable, and subtype-selective P2Y2 receptor agonist with an EC50 of 134 nM. It displays >50-fold selectivity versus the P2Y4 (EC50 of 9.3 μM) and P2Y6 (EC50 of 7.0 μM) receptors.
Appearance: Solid
Color: Light yellow to yellow
Shipping: Room temperature in continental US; may vary elsewhere.
Storage: -20°C, sealed storage, away from moisture. In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture).
Solubility (in vitro): H2O: ≥ 100 mg/mL
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