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Oxybuprocaine hydrochloride is a short-acting ester local anesthetic used topically to produce surface anesthesia by reversibly blocking voltage-gated sodium channels and preventing propagation of painful nerve impulses in ocular tissues. It is intended for research and analytical applications requiring a topical anesthetic agent.
Short-acting ester local anesthetic for topical applications.
Reversibly blocks voltage-gated sodium channels to prevent nerve impulse propagation.
Suitable for ophthalmic and otolaryngologic research applications.
HCl salt form with CAS 5987-82-6 and molecular weight 344.88 g/mol.
Supplied in a 10 MG research pack suitable for analytical and preclinical use.
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2-(Fmoc-amino)-3-(1-Boc-3-piperidyl)propanoic Acid is a Amino Acid reagent (Subcategory: Unusual AA) sold by WuXi TIDES. Offered in 50 g. Store at 4 °C. SDS available for reference.
Specifications - CAS: 457060-97-8 - MDL: MFCD02683129 - InChIKey: WPCUPMFUJBWUFE-UHFFFAOYSA-N - Molecular Weight: 494.588 - Molecular Formula: C28H34N2O6 - Purity: ≥95% - Container Type: 250 mL HDPE - Pack Size: 50 g - Net Weight: 50 g - Gross Weight: 89.8 g - Commodity Code: 29333999 - Country Of Origin: China - IUPAC: 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-(tert-butoxycarbonyl)piperidin-3-yl)propanoic acid - SMILES: CC(OC(N1CCCC(CC(C(O)=O)NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)C1)=O)(C)C
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Teneligliptin hydrobromide is an orally active and selective dipeptidyl peptidase 4 (DPP-4) inhibitor, demonstrating IC50s of 0.37 nM for human DPP-4 and 0.29 nM for rat DPP-4. This compound improves blood glucose levels and is utilized in research pertaining to type 2 diabetes mellitus.
Prevents activation of the NLRP3 inflammasome and associated injury.
Protects against hypoxia/reoxygenation-induced endothelial cell injury by reducing reactive oxygen species.
Inhibits inflammation and apoptosis induced by doxorubicin.
Ameliorates diabetic polyneuropathy and enhances pancreatic β-cell volume and insulin secretion.
Attenuates myocardial hypertrophy, injury, and inflammatory response in diabetic models.
Prevents obesity and obesity-related manifestations by boosting energy expenditure.
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L-Leucinamide hydrochloride is the hydrochloride salt of L-leucinamide, an amino acid derivative reported to have anti-inflammatory properties. The product is supplied as a solid for research use, with specified purity and recommended storage conditions.
Hydrochloride salt, solid form.
Purity 97.0% (NMR).
Molecular formula C6H15ClN2O, molecular weight 166.65 g·mol⁻¹.
CAS number 10466-61-2.
Packaging: 25 g; recommended storage: powder at -20°C for up to 3 years or 4°C for up to 2 years.
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(S)-Tomoxetine hydrochloride is the S-enantiomer of tomoxetine supplied as a white to off-white solid for research and analytical applications. It is an isomer of a norepinephrine reuptake inhibitor and is reported to inhibit norepinephrine reuptake with a Ki of 16.8 nM; not for human use.
High purity: 99.8%.
Appearance: white to off-white solid.
Reported activity: norepinephrine reuptake inhibition (Ki = 16.8 nM).
Solubility: DMSO 100 mg/mL (requires ultrasonic).
Recommended storage: powder -20 °C (up to 3 years) or 4 °C (up to 2 years).
Available pack sizes: 5 MG, 10 MG, larger sizes by quote.
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Norfluoxetine hydrochloride is an active N-demethylated metabolite of Fluoxetine. Fluoxetine is a selective serotonin (5-HT) reuptake inhibitor that is metabolized to Norfluoxetine hydrochloride by cytochrome P450 (CYP) 2D6, CYP2C19, and CYP3A4. Norfluoxetine hydrochloride inhibits 5-HT uptake and inhibits CaV3.3 T current (IC50 = 5 μM). It also has anticonvulsant activity.
Inhibits 5-HT uptake.
Inhibits CaV3.3 T current (IC50 = 5 μM).
Exhibits anticonvulsant activity.
Pretreatment with Norfluoxetine hydrochloride (20 mg/kg s.c.) significantly increases both the rate and duration of survival, demonstrating a significant protective effect against Pentylenetetrazol-induced epilepsy.
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