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ACTB-1003 (CAS 939805-30-8) also known as EOC317 is an orally bioavailable small-molecule kinase inhibitor that selectively targets fibroblast growth factor receptor 1 (FGFR1) vascular endothelial growth factor receptor 2 (VEGFR2) and the endothelial-specific tyrosine kinase Tie-2 In vitro studies demonstrate that ACTB-1003 suppresses the activity of these kinases at nanomolar concentrations By modulating these angiogenesis-associated signaling pathways ACTB-1003 serves as a valuable tool for investigating tumor angiogenesis and related signal transduction mechanisms in biomedical research
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6-azido-1-hexanamine is an azide-functionalized hexylamine reagent used as a cleavable linker in antibody-drug conjugate (ADC) synthesis and for click chemistry conjugation. It provides an azide handle for azide-alkyne cycloaddition reactions and is supplied as a colorless to light yellow liquid.
CAS number 349553-73-7
Molecular formula C6H14N4
Molecular weight 142.20 g/mol
Purity 98.7%
Pack size 500 mg
Storage 4°C, protect from light; in solvent: -80°C (6 months), -20°C (1 month)
Applications ADC linker synthesis and click chemistry conjugation
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