Choose the brand aligned with your industry so we can best serve your needs.
For researchers, scientists, and technical professionals: Your one-stop shop for the complete range of laboratory, production, and safety products and services.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Amlodipine besylate (Amlodipine benzenesulfonate) is an orally active dihydropyridine calcium channel blocker and antianginal agent. It functions by blocking voltage-dependent L-type calcium channels, inhibiting initial calcium influx. This compound can be used for research into high blood pressure and cancer.
Blocks voltage-dependent L-type calcium channels
Inhibits initial influx of calcium
Useful for high blood pressure research
Useful for cancer research
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
TO-1187 TFA is a selective HDAC6 PROTAC degrader with a DC50 of 5.81 nM. It functions by promoting the ubiquitination and degradation of HDAC6 and can be used in the study of hematological malignancies and solid tumors. The compound is described as being composed of an HDAC6 ligand (HY-173386), a CRBN ligase ligand (HY-41547), and a linker (HY-140212).
Selective HDAC6 PROTAC degrader (DC50: 5.81 nM).
Promotes the ubiquitination and degradation of HDAC6.
Applicable in the study of hematological malignancies and solid tumors.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Amlodipine maleate (CAS No 88150-47-4) is a calcium channel blocker commonly used in cardiovascular research Originating from the dihydropyridine class its mechanism of action involves inhibiting the influx of calcium ions through L-type calcium channels leading to vasodilation and reduced blood pressure This compound has demonstrated in vitro activity in the nanomolar to low micromolar range making it a valuable tool for studying cardiac function and vascular smooth muscle relaxation It is often utilized in cell models including cardiomyocytes and endothelial cells as well as in animal studies to explore hypertension and related pathologies Additionally amlodipine maleate is employed in high-throughput drug screening assays to identify potential therapeutic agents Experimental concentrations typically depend on the specific research design
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More