TO-1187 TFA is a selective PROTAC degrader designed to target HDAC6, effectively promoting its ubiquitination and subsequent degradation. It is a valuable tool for research into hematological malignancies and solid tumors, composed of an HDAC6 ligand, a CRBN ligase ligand, and a linker.
- Selective PROTAC degrader for HDAC6
- Promotes ubiquitination and degradation of HDAC6
- Useful for studying hematological malignancies and solid tumors
- Provided as a light yellow to yellow solid
- Soluble in DMSO at 100 mg/mL