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RP-1664 is a selective and orally active PLK4 inhibitor with an IC50 of 3 nM. It demonstrates selectivity over related kinases like AURKA/B and PLK1. This compound disrupts centriole biogenesis in cancer cells, leading to an accumulation of PLK4 and p21 protein. RP-1664 shows increased sensitivity in TRIM37-high-expressing cells or tumors and exhibits anti-tumor activity in breast cancer and neuroblastoma research.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Desethyl chloroquine diphosphate is the diphosphate salt of desethyl chloroquine, a primary desethyl metabolite of chloroquine. It is provided as a research-grade antiplasmodic compound for biochemical and pharmacological studies, offered at high purity and in small pack sizes suitable for laboratory experiments.
High reported purity (99.7%).
Available in small pack sizes, including 10 mg.
Supplied as the diphosphate salt.
Molecular formula C16H28ClN3O8P2; molecular weight 487.81.
Suitable for biochemical and pharmacological research applications.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More