Organosulfur Compounds
ALADDIN SCIENTIFIC CORPORATION Sulfanilamide, 100g
Sulfonamide antibacterial Sulfanilamide is an antibacterial and used in the treatment of vaginal yeast infections It is a competitive inhibitor of dihydropteroate synthestase to block the synthesis of folic acid It serves as an intermediate for the preparation of 26-disubstituted anilines by electrophilic substitution followed by removal of the sulfonamide blocking group by desulfonation with sulfuric acid
Medchemexpress LLC Fura-2 pentapotassium | 113694-64-7 | 97.0% | 500 UG
Fura-2 pentapotassium is a cell-impermeable scaled fluorescent dye utilized for intracellular calcium imaging. It exhibits an emission wavelength of 510 nm and excitation wavelengths of 340 nm or 380 nm. The ratio of 340/380 fluorescence intensity directly corresponds to the intracellular Ca2+ level. Since it cannot permeate the cell membrane, various methods are employed for its introduction into the cytoplasm of cells.
- Utilized for intracellular calcium imaging
- Emission wavelength of 510 nm
- Excitation wavelengths of 340 nm or 380 nm
- Ratio of fluorescence intensity is proportional to intracellular Ca2+ level
- Requires methods like microinjection for cellular uptake
Medchemexpress LLC Sulfathiazole | 72-14-0 | 99.7% | 10 G
Sulfathiazole is an orally active endocrine disruptor that targets the steroidogenic pathway. It enhances the activity of CYP19 in human adrenal cancer cells (H295R) and has endocrine-disrupting effects on aquatic organisms.
- Enhances CYP19 activity in human adrenal cancer cells (H295R).
- Upregulates mRNA expression of CYP17, CYP19, and 3β-HSD.
- Increases production of 17-estradiol (E2).
- Exhibits endocrine-disrupting effects on aquatic organisms like the Japanese medaka fish.
- For research use only.
Medchemexpress LLC Sulfathiazole | 72-14-0 | 99.7% | 5 G
Sulfathiazole is an orally active compound identified as an endocrine disruptor. It specifically targets the steroidogenic pathway by enhancing the activity of CYP19 in human adrenal cancer cells (H295R) and increasing the mRNA expression of CYP17, CYP19, and 3β-HSD. This leads to an increased production of 17-estradiol (E2) and has been observed to cause endocrine disrupting effects on aquatic organisms such as the Japanese medaka fish.
- Orally active.
- Targets the steroidogenic pathway.
- Enhances CYP19 activity in human adrenal cancer cells (H295R).
- Upregulates mRNA expression of CYP17, CYP19, and 3β-HSD.
- Increases 17-estradiol (E2) production.
- Exhibits endocrine disrupting effects on aquatic organisms (e.g., Japanese medaka fish).
- Can inhibit the corrosion of copper in 0.1 M NaCl solution, with efficiency exceeding 80% at increased concentrations.
Medchemexpress LLC Sulforaphane | 4478-93-7 | 99.0% | 177.29 | 500 MG
Sulforaphane is an orally active inducer of the Keap1/Nrf2/ARE pathway. It promotes the transcription of tumor-suppressing proteins and effectively inhibits the activity of HDACs. By activating the Keap1/Nrf2/ARE pathway and further inducing HO-1 expression, Sulforaphane protects the heart. It suppresses high glucose-induced pancreatic cancer through AMPK-dependent signal transmission and exhibits both anticancer and anti-inflammatory properties.
- Orally active inducer of the Keap1/Nrf2/ARE pathway.
- Promotes transcription of tumor-suppressing proteins.
- Effectively inhibits HDACs activity.
- Protects the heart.
- Suppresses high glucose-induced pancreatic cancer.
- Exhibits anticancer and anti-inflammatory properties.
- Induces cell cycle arrest and apoptosis.
- Reduces ROS production and cell apoptosis.
eMolecules 67-68-5 | Dimethyl sulfoxide | Combi-Blocks, Inc. | MFCD00002089 | 78.130 | C2H6OS | 95.000 | CS(C)=O | 500g | 642100602
Dimethyl sulfoxide | Combi-Blocks, Inc. | 67-68-5 | MFCD00002089 | 78.130 | C2H6OS | 95.000 | CS(C)=O | 500g | 642100602
Medchemexpress LLC CXCR7 modulator 2 | 2227426-37-9 | 98.71% | 522.68 | 1 ML
CXCR7 modulator 2 is a modulator of C-X-C Chemokine Receptor Type 7 (CXCR7), with a Ki of 13 nM. It is for research use only and not sold to patients. This modulator offers protection against cardiac injury.
- Potent CXCR7-binding affinity (Ki=13 nM).
- β-arrestin activity (EC50=11 nM).
- Improved selectivity in the GPCR panel.
- Improved therapeutic index in the hERG patch-clamp assay.
- Moderate to high in vitro turnover in NADPH-supplemented mouse-liver microsomes (MLM, 93 μL/min/mg) and hepatocytes (28 μL/min per million cells).
- Good aqueous solubility.
- Rapidly absorbed with a mean maximal plasma concentration (Cmax) of 682 ng/mL at 0.25 h (Tmax).
- Reduces cardiac fibrosis in an isoproterenol-induced cardiac injury model in mice.
eMolecules 67-68-5 | Dimethyl sulfoxide, meets analytical specification of Ch.P. | ChemScene | MFCD00002089 | 78.130 | C2H6OS | 99.000 | CS(C)=O | 550g | 717421097
Dimethyl sulfoxide, meets analytical specification of Ch.P. | ChemScene | 67-68-5 | MFCD00002089 | 78.130 | C2H6OS | 99.000 | CS(C)=O | 550g | 717421097
Cayman Chemical Sulindac sulfide, Purity: ≥98%, CAS: 49627-27-2, 10 mg
An active metabolite of sulindac; inhibits COX-1 and COX-2 (IC50s = 1.9 and 1.21 µM, respectively); inhibits aldose reductase (IC50 = 279 nM), blocking NADPH-dependent reduction of glucose to sorbitol, and reducing type 2 diabetic complications; inhibits colorectal cancer growth in vitro and in vivo
Medchemexpress LLC Kv3 modulator 2 | 2101321-76-8 | 99.9% | 25 MG
Kv3 modulator 2 is a potent Kv3 channels modulator, extracted from patent WO2018109484A1. It exhibits analgesic activity and is utilized in the prophylaxis or treatment of related disorders. This compound is for research use only and is not intended for patient use. It has a molecular weight of 379.41 and a chemical formula of C21H21N3O4, appearing as a solid that is white to off-white in color.
- Potent Kv3 channels modulator
- Exhibits analgesic activity
- Used in the prophylaxis or treatment of related disorders
- For research use only
- Molecular weight: 379.41
- Chemical formula: C21H21N3O4
- Appearance: Solid, white to off-white
- Shipped at room temperature in the continental US
- Storage conditions: 4°C sealed, away from moisture and light; in solvent: -80°C for 6 months or -20°C for 1 month (sealed storage, away from moisture and light)
- Solubility: 100 mg/mL in DMSO
Medchemexpress LLC 2,4-Pentanedione, 3-pentadecylidene- | 1314006-43-3 | C20H36O2 | 25 MG
2,4-Pentanedione, 3-pentadecylidene- | 1314006-43-3 | C20H36O2 | 25 MG