Organosulfur Compounds
Medchemexpress LLC 1-Piperidinyloxy, 4-azido-2,2,6,6-tetramethyl- | 63697-61-0 | C9H17N4O | 25 MG
N3-TEMPO is a click chemistry reagent containing an azide group. It can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups, and ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. Click chemistry is utilized in many research fields due to its high yield, high specificity, and simplicity, and has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules.
- Contains an azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition with alkyne groups
- Undergoes ring strain-promoted alkyne-azide cycloaddition with DBCO or BCN groups
- Utilized for high yield, high specificity, and simplicity in click chemistry
- Potential for binding between nucleic acids, lipids, proteins, and other molecules
Medchemexpress LLC N3-TEMPO | 63697-61-0 | C9H17N4O* | 5 MG
N3-TEMPO is a click chemistry reagent that contains an azide group. It is useful for binding between nucleic acids, lipids, proteins, and other molecules due to its high yield, specificity, and simplicity. It can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, and ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
- Click chemistry reagent
- Azide compound
- Suitable for antibody-drug conjugate/ADC related research
- Can be used as an ADC linker
Medchemexpress LLC 4-azido-2,2,6,6-tetramethyl-1-piperidinyloxy | 63697-61-0 | MFCD16659950 | 99.4% | 197.26 g/mol | C9H17N4O | 10 MG
N3-TEMPO is an azide-functionalized TEMPO derivative used to introduce a nitroxide spin label via click chemistry. It participates in copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC), enabling efficient conjugation and labeling of biomolecules. The compound is supplied as a high-purity solid for research applications.
- Azide-functionalized TEMPO for click chemistry.
- Reacts in CuAAC and SPAAC for efficient conjugation.
- Introduces a stable nitroxide spin label for EPR and probing studies.
- High purity suitable for research-grade applications.
- Solid form for convenient storage and handling.
- Useful for labeling proteins, nucleic acids, lipids, and small molecules.
Medchemexpress LLC Sulfathiazole | 72-14-0 | 99.7% | 1 ML
Sulfathiazole is an orally active endocrine disruptor that targets the steroidogenic pathway. It enhances CYP19 activity in human adrenal cancer cells and upregulates the mRNA expression of CYP17, CYP19, and 3β-HSD. This compound increases 17-estradiol (E2) production and exhibits endocrine disrupting effects on aquatic organisms.
- Orally active endocrine disruptor
- Targets the steroidogenic pathway
- Enhances CYP19 activity in human adrenal cancer cells
- Upregulates mRNA expression of CYP17, CYP19, and 3β-HSD
- Increases 17-estradiol (E2) production
- Exhibits endocrine disrupting effects on aquatic organisms
- Shows antibacterial properties
- Effective in inhibiting copper corrosion in 0.1 M NaCl solution
Medchemexpress LLC Sulfathiazole (sodium) | 144-74-1 | 99.9% | 1 ML
Sulfathiazole sodium is an analytical standard suitable for research and analytical applications such as HPLC, GC, and MS. It acts as an orally active endocrine disruptor, notably enhancing CYP19 activity in human adrenal cancer cells (H295R) and upregulating the mRNA expression of CYP17, CYP19, and 3β-HSD. The compound also increases 17-estradiol (E2) production and exhibits endocrine disrupting effects on aquatic organisms. Furthermore, it functions as a cathodic corrosion inhibitor by reducing corrosion current density and shifting corrosion potential negatively.
- Enhances CYP19 activity in human adrenal cancer cells
- Upregulates mRNA expression of CYP17, CYP19, and 3β-HSD
- Increases 17-estradiol (E2) production
- Exhibits endocrine disrupting effects on aquatic organisms
- Inhibits copper corrosion by chloride ions
Medchemexpress LLC Sulfathiazole | 72-14-0 | 99.7% | 5 G
Sulfathiazole is an orally active compound identified as an endocrine disruptor. It specifically targets the steroidogenic pathway by enhancing the activity of CYP19 in human adrenal cancer cells (H295R) and increasing the mRNA expression of CYP17, CYP19, and 3β-HSD. This leads to an increased production of 17-estradiol (E2) and has been observed to cause endocrine disrupting effects on aquatic organisms such as the Japanese medaka fish.
- Orally active.
- Targets the steroidogenic pathway.
- Enhances CYP19 activity in human adrenal cancer cells (H295R).
- Upregulates mRNA expression of CYP17, CYP19, and 3β-HSD.
- Increases 17-estradiol (E2) production.
- Exhibits endocrine disrupting effects on aquatic organisms (e.g., Japanese medaka fish).
- Can inhibit the corrosion of copper in 0.1 M NaCl solution, with efficiency exceeding 80% at increased concentrations.
Medchemexpress LLC Sulfathiazole | 72-14-0 | MFCD00005319 | 99.7% | 1 G
Sulfathiazole is an orally active endocrine disruptor that targets the steroidogenic pathway. It specifically enhances the activity of CYP19 in human adrenal cancer cells (H295R) and upregulates the mRNA expression of CYP17, CYP19, and 3β-HSD. It also increases the production of 17-estradiol (E2) and demonstrates endocrine disrupting effects on aquatic organisms like the Japanese medaka fish.
- Targets the steroidogenic pathway
- Enhances CYP19 activity in human adrenal cancer cells (H295R)
- Upregulates mRNA expression of CYP17, CYP19, and 3β-HSD
- Increases production of 17-estradiol (E2)
- Demonstrates endocrine disrupting effects on aquatic organisms
- Can inhibit copper corrosion in 0.1 M NaCl solution
- Increases plasma 17-estradiol concentrations in male Japanese medaka models
Sigma Aldrich Fine Chemicals Biosciences Fluorescein isothiocyanate5G
Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166) linkages. The remaining (163) linkages account for the branching of dextran. Conflicting data on the branch lengths implies that the average branch length is less than three glucose units. However other methods indicate branches of greater than 50 glucose units exist. Native dextran has been found to have a molecular weight (MW) in the range of 9 million to 500 million. Lower MW dextrans will exhibit slightly less branching and have a more narrow range of MW distribution. Dextrans with MW greater than 10 000 behave as if they are highly branched. As the MW increases dextran molecules attain greater symmetry. Dextrans with MW of 2 000 to 10 000 exhibit the properties of an expandable coil. At MW below 2 000 dextran is more rod-like. The MW of dextran is measured by one or more of the following methods low angle laser light scattering size exclusion chromatography copper-complexation and anthr
