Phenylpropanoids and polyketides
Medchemexpress LLC 5,7-Dimethoxyflavone | 21392-57-4 | 100 MG
5,7-Dimethoxyflavone is a natural compound found in *Kaempferia parviflora* that exhibits diverse biological activities. It possesses anti-obesity, anti-inflammatory, and antineoplastic effects. This compound is known to inhibit cytochrome P450 (CYP) 3As and acts as a potent Breast Cancer Resistance Protein (BCRP) inhibitor.
- Inhibits cytochrome P450 (CYP) 3As
- Potent Breast Cancer Resistance Protein (BCRP) inhibitor
- Exhibits anti-obesity effects
- Demonstrates anti-inflammatory properties
- Shows antineoplastic activity
- Reduces liver CYP3A11 and CYP3A25 protein expression in mice
- Inhibits sarcopenia in aged mice
- Decreases body weight gain and inhibits fatty liver in HFD mice
Medchemexpress LLC Nicotiflorin | 17650-84-9 | 594.52 | 1 ML
Nicotiflorin is a flavonoid glycoside extracted from the traditional Chinese medicine *Carthamus tinctorius*. It exhibits potent antiglycation activity and neuroprotection effects.
- Flavonoid glycoside
- Extracted from Carthamus tinctorius
- Potent antiglycation activity
- Neuroprotection effects
- Attenuates cell death and reduces LDH release in cultured neurons
- Increases eNOS activity, mRNA, and protein levels in cultured rat cerebral blood vessel endothelial cells
- Reduces brain infarct volume and neurological deficits in rats following cerebral ischemia
TARGETMOL CHEMICALS INC PUERARIN 6-O-XYLOSIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Puerarin 6''-O-xyloside possesses significant anti-osteoporotic activity on ovariectomy mice it has significant antitumour activities the mechanisms are related to increased levels of caspase-3 caspase-7 caspase-9 and Bax and reduced levels Bcl-2. purity: 98%
Medchemexpress LLC Luteolin 7-O-glucuronide | 29741-10-4 | 462.36 | 1 ML
Luteolin 7-O-glucuronide is an inhibitor of Matrix Metalloproteinases (MMP) activities, with IC50s of 17.63, 7.99, 11.42, 12.85, and 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, and MMP-13, respectively. It is intended for research use only.
- Inhibits NO production and mRNA expression of inflammatory mediators in LPS-stimulated RAW 264.7 macrophages.
- Inhibits NF-κB, p38, and JNK activation in LPS-stimulated RAW 264.7 macrophages.
- Improves depression-like and stress coping behaviors in mouse sleep deprivation models.
- Reduces increased immobility time and plasma corticosterone levels.
- Reduces TNF-α and IL-1β levels and increases BDNF mRNA expression in the hippocampus of sleep-deprived mice.
Medchemexpress LLC Xanthohumol C | 189299-05-6 | 352.38 | 5 MG
Xanthohumol C is a prenylchalcone that can be isolated from the hops of Humulus lupulus. It is categorized as a natural compound with a molecular weight of 352.38 and a chemical formula of C21H20O5. This compound appears as a light yellow to yellow solid and is intended for research use only, not for sale to patients.
- It is a prenylchalcone, a type of natural compound.
- It can be isolated from the hops of Humulus lupulus.
- It exhibits cytotoxicity against human HeLa cells with an IC50 of 12.5 μM.
- It shows antiproliferative activity against human MCF7 cells with IC50 values of 15.7 μM (2 days) and 6.87 μM (4 days).
Medchemexpress LLC 1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one | 149732-52-5 | 292.33 | 5 MG
1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one is a potent nucleocapsid (N) protein inhibitor isolated from *Curcuma kwangsiensis*. It demonstrates excellent antiviral activity against HCoV-OC43 and SARS-CoV-2.
- Inhibits nucleocapsid (N) protein
- Exhibits antiviral activity against HCoV-OC43 and SARS-CoV-2
- Active against various cell lines (KB, PC-12, Vero)
Medchemexpress LLC Hesperidin methylchalcone | 1 g | | HY-126382-1g | 24292-52-2 | MW: 624.59
Hesperidin methylchalcone (Hesperidin methyl chalcone) is an orally active flavonoid that has analgesic, anti-inflammatory and antioxidant properties. Hesperidin methylchalcone exhibits vasoprotective activity. Hesperidin methylchalcone inhibits oxidative stress, cytokine production and NF-κB activation. Hesperidin methylchalcone can be used for the research of gout disease.
Apexbio Technology LLC Daidzein 486-66-8 5g
Daidzein is an isoflavone compound derived from soybeans structurally classified as a phytoestrogen with structural similarity to endogenous estrogen It has been widely investigated for its potential in biomedical research particularly in oncology and cell biology studies Daidzein exhibits anticancer-related biological activity possibly via modulation of hormonal signaling pathways and interference with cell cycle progression as exemplified by inducing cell cycle arrest at the G1 phase in cultured mammalian cells Additionally it demonstrates antioxidant properties providing protective effects against oxidative stress-mediated cell injury such as hepatic cellular damage induced by chemical carcinogens Daidzein is thus employed in studies focused on hormone-dependent tumorigenesis cell-cycle regulation mechanisms and oxidative-stress-induced cellular responses
Medchemexpress LLC Cinnamyl acetate | 103-54-8 | 500 G
Cinnamyl acetate is a chemical compound widely utilized in the flavor and fragrance industry, and it also acts as a broad-spectrum antibacterial agent.
- Functions as a broad-spectrum antibacterial agent
- Used extensively in the flavor and fragrance industry
- Molecular formula C11H12O2
- Molecular weight 176.21
- Appears as a colorless to light yellow liquid
- Stable under recommended storage conditions