Phenylpropanoids and polyketides
Apexbio Technology LLC Epothilone D 189453-10-9 2mg
Epothilone D (189453-10-9) is a small-molecule microtubule-stabilizing agent It is designed to stabilize microtubules thereby disrupting essential cellular processes such as mitosis Epothilone D exerts its biological activity primarily through inhibition of microtubule depolymerization In in vitro assays Epothilone D demonstrates cytotoxic activity with IC50 values of 2 9 nM in MCF-7 cells 2 7 nM in KB-31 cells and 9 5 nM in CCRF-CEM cells Based on these pharmacological properties Epothilone D holds research potential in oncology and the study of drug resistance in cancer
Medchemexpress LLC Epothilone B | 152044-54-7 | 99.9% | 507.68 | 1 ML
Epothilone B is a microtubule stabilizer (MSA) with a Ki of 0.71μM and possesses blood-brain barrier permeability. It functions by binding to the αβ-tubulin heterodimer subunit, which leads to a decrease in αβ-tubulin dissociation. It is intended for research use only and is not sold to patients.
- Microtubule stabilizer (MSA)
- Blood-brain barrier permeability
- Binds to the αβ-tubulin heterodimer subunit
- Decreases αβ-tubulin dissociation
Apexbio Technology LLC Epothilone D 189453-10-9 5mg
Epothilone D (189453-10-9) is a small-molecule microtubule-stabilizing agent It is designed to stabilize microtubules thereby disrupting essential cellular processes such as mitosis Epothilone D exerts its biological activity primarily through inhibition of microtubule depolymerization In in vitro assays Epothilone D demonstrates cytotoxic activity with IC50 values of 2 9 nM in MCF-7 cells 2 7 nM in KB-31 cells and 9 5 nM in CCRF-CEM cells Based on these pharmacological properties Epothilone D holds research potential in oncology and the study of drug resistance in cancer
Abcam Epothilone D, Microtubule-stabilizing agent, 5MG
MW 491.7 Da. Microtubule-stabilizing agent. Epothilone A (ab143615) and B (ab141271) analog. Improves microtubule density and axonal integrity Shows antineoplastic and neuroprotective effects in vivo. Blood-brain barrier permeable.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC CE(20:5(5Z,8Z,11Z,14Z,17Z) | 74892-97-0 | 99.9% | 671.09 | 1 MG
CE(20:5(5Z,8Z,11Z,14Z,17Z) is an endogenous metabolite intended for research use only and not for patient use. It presents as a colorless to light yellow liquid.
- Endogenous metabolite
- Colorless to light yellow liquid
- Chemical formula C47H74O2
- Classified under steroids and natural products
- Recommended shipping at room temperature in continental US
- Solution storage at -20°C for 2 years
Cayman Chemical 5Z 11Z 15R15HydroxyeIcosa
A stable isomer of 15(S)-HETE that elicits contraction of isolated pulmonary arteries from rabbits and inhibits the proliferation and migration of PC-3 cells
Medchemexpress LLC Zearalenone | 17924-92-4 | MFCD00133085 | 98.9% | 318.4 g/mol | C18H22O5 | 5 MG
Analytical reference standard of the mycotoxin zearalenone intended for research and analytical applications. Supplied as a 5 mg standard with high purity for method development, calibration, and quality control.
- Analytical reference standard for mycotoxin testing.
- Suitable for method development and calibration.
- High purity (98.9%).
- White microcrystals or powder form for ease of handling.
Apexbio Technology LLC Zearalenone(Synonyms: F-2 toxin, Mycotoxin F2, Zearalenolactone, RAL, ZEA, Zenon), 50mg, CAS: 17924-92-4.
Zearalenone (CAS 17924-92-4) is a mycotoxin produced primarily by Fusarium fungi frequently contaminating feed and food products It exhibits estrogenic activity through interaction with estrogen receptors thus altering endocrine signaling pathways Although acutely low in toxicity zearalenone effectively modulates estrogen receptor-mediated responses influencing hormonal balance in livestock species such as pigs cattle and sheep In biomedical research zearalenone serves as a tool compound to study estrogen receptor-mediated mechanisms and endocrine disruption particularly in young animals within veterinary pharmacological contexts