Phenylpropanoids and polyketides
Quercetin dihydrate, 97%
CAS: 6151-25-3 Molecular Formula: C15H14O9 Molecular Weight (g/mol): 338.27 MDL Number: MFCD00149487 InChI Key: GMGIWEZSKCNYSW-UHFFFAOYSA-N Synonym: quercetin dihydrate,2-3,4-dihydroxyphenyl-3,5,7-trihydroxy-4h-chromen-4-one dihydrate,quercetine dihydrate,quercetin, dihydrate,ccris 3304,3,3',4',5,7-pentahydroxyflavone dihydrate,quercetin dihydrate sophoretin,flavone, 3,3',4',5,7-pentahydroxy-, dihydrate,dsstox_cid_1219,2-3,4-dihydroxyphenyl-3,5,7-trihydroxy-4h-1-benzopyran-4-one dihydrate PubChem CID: 5284452 IUPAC Name: 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one;dihydrate SMILES: O.O.OC1=CC(O)=C2C(OC(=C(O)C2=O)C2=CC=C(O)C(O)=C2)=C1
Chlortetracycline hydrochloride
CAS: 64-72-2 Molecular Formula: C22H24Cl2N2O8 Molecular Weight (g/mol): 515.34 MDL Number: MFCD00082440 InChI Key: QYAPHLRPFNSDNH-CIVPRPTRSA-N Synonym: chlortetracycline hydrochloride,4-epi-chlortetracycline hydrochloride,2-amino hydroxy methylidene-7-chloro-4-dimethylamino-6,10,11,12a-tetrahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione hydrochloride,2-azanyl oxidanyl methylidene-7-chloranyl-4-dimethylamino-6-methyl-6,10,11,12a-tetrakis oxidanyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione hydrochloride PubChem CID: 66577600 IUPAC Name: (4S,4aR,5aS,6S,12aR)-7-chloro-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride SMILES: CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C(C=CC(=C41)Cl)O)O)O)O)C(=O)N)N(C)C)O.Cl
Medchemexpress LLC Myricetin 3'-glucoside | 520-14-9 | 1 MG
Myricetin 3'-glucoside is a glycoside derivative of quercetin. It significantly prevents ethanol-induced hepatotoxicity by reducing hepatic transaminase activity and inflammatory response in HepG2 cells, demonstrating a protective effect on alcohol-induced liver injury.
- Glycoside derivative of quercetin
- Prevents ethanol-induced hepatotoxicity
- Reduces hepatic transaminase activity
- Reduces inflammatory response in HepG2 cells
- Protective effect on alcohol-induced liver injury
Medchemexpress LLC Sor-C13 Tfa | 99.3% | 1565.81 (free acid) | 5 MG
SOR-C13 TFA is a carboxy-terminal truncated peptide that acts as a high-affinity TRPV6 antagonist with an IC50 value of 14 nM. TRPV6 is a non-voltage gated calcium channel associated with malignancy and poor prognosis in breast cancer. This peptide exhibits anticancer activity and is intended for research use only.
- High-affinity TRPV6 antagonist
- IC50 value of 14 nM against TRPV6
- Demonstrated anticancer activity
- Effectively inhibits tumor growth in vivo
- White to off-white solid appearance
- Soluble in H2O and DMSO at 100 mg/mL (with ultrasonic)
- Recommended storage conditions for powder: -80°C for 2 years, -20°C for 1 year
- Recommended storage conditions in solvent: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC SOR-C13 TFA | 1187852-48-7 | 99.3% | 1565.81 (free acid) | 50 MG
SOR-C13 TFA is a carboxy-terminal truncated peptide that acts as a high-affinity TRPV6 antagonist, exhibiting an IC50 value of 14 nM. TRPV6 is a non-voltage gated calcium channel implicated in malignancy and poor prognosis in breast cancer. This compound has demonstrated anticancer activity.
- High-affinity TRPV6 antagonist with an IC50 of 14 nM.
- TRPV6 is associated with malignancy and poor prognosis in breast cancer.
- Exhibits anticancer activity.
- In vivo studies showed effective inhibition of tumor growth in female NOD/SCID mice with SKOV-3 cells at dosages of 400, 600, and 800 mg/kg (IP; daily; on days 1 to 12).
- Has been investigated in clinical trials for cancer and advanced malignant solid neoplasm.
Apexbio Technology LLC trans-9-Tetradecenoic acid 50286-30-1 10mg
trans-9-Tetradecenoic acid (CAS 50286-30-1) is a monounsaturated fatty acid comprising a 14-carbon chain with a trans double bond at the ninth carbon It occurs naturally in select plant oils dairy products and as a metabolic intermediate in certain microorganisms By serving as a substrate or modulator within fatty acid metabolic pathways trans-9-Tetradecenoic acid is utilized in biochemical studies to investigate lipid metabolism fatty acid desaturation and associated physiological processes Its presence in biological systems also makes it relevant for research on dietary lipids and their roles in health and disease
Apexbio Technology LLC Entacapone 130929-57-6 10mg
Entacapone (CAS 130929-57-6) is a selective second-generation inhibitor of catechol-O-methyltransferase (COMT) It demonstrates potent inhibition of total COMT in mouse liver with reported IC50 and Ki values of 20 1 nM and 10 7 nM respectively In rat models IC50 values for soluble COMT and membrane-bound COMT are 14 3 nM and 73 3 nM Entacapone is primarily utilized in research as an adjunct to levodopa and dopa decarboxylase inhibitor regimens in Parkinson s disease studies given its ability to suppress the formation of 3-O-methyldopa thereby enhancing levodopa bioavailability and prolonging its pharmacological effect
Apexbio Technology LLC Entacapone 130929-57-6 100mg
Entacapone (CAS 130929-57-6) is a selective second-generation inhibitor of catechol-O-methyltransferase (COMT) It demonstrates potent inhibition of total COMT in mouse liver with reported IC50 and Ki values of 20 1 nM and 10 7 nM respectively In rat models IC50 values for soluble COMT and membrane-bound COMT are 14 3 nM and 73 3 nM Entacapone is primarily utilized in research as an adjunct to levodopa and dopa decarboxylase inhibitor regimens in Parkinson s disease studies given its ability to suppress the formation of 3-O-methyldopa thereby enhancing levodopa bioavailability and prolonging its pharmacological effect
Apexbio Technology LLC Entacapone 130929-57-6 10mM (in 1mL DMSO)
Entacapone (CAS 130929-57-6) is a selective second-generation inhibitor of catechol-O-methyltransferase (COMT) It demonstrates potent inhibition of total COMT in mouse liver with reported IC50 and Ki values of 20 1 nM and 10 7 nM respectively In rat models IC50 values for soluble COMT and membrane-bound COMT are 14 3 nM and 73 3 nM Entacapone is primarily utilized in research as an adjunct to levodopa and dopa decarboxylase inhibitor regimens in Parkinson s disease studies given its ability to suppress the formation of 3-O-methyldopa thereby enhancing levodopa bioavailability and prolonging its pharmacological effect
Sigma Aldrich 5-Bromoindoxyl acetate
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
