Phenylpropanoids and polyketides
![Methyl Calcein Blue Hydrate [Indicator for complexometry Copper], TCI America™](https://assets.fishersci.com/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-81028-96-8.jpg-250.jpg)
Methyl Calcein Blue Hydrate [Indicator for complexometry Copper], TCI America™
CAS: 81028-96-8 Molecular Formula: C14H15NO5 Molecular Weight (g/mol): 277.276 MDL Number: MFCD00167005 InChI Key: KRMRPQPGZHQMDD-UHFFFAOYSA-N Synonym: 4-Methylumbelliferonemethylene-N-methylglycine PubChem CID: 5384392 IUPAC Name: 2-[(7-hydroxy-4-methyl-2-oxochromen-6-yl)methyl-methylamino]acetic acid SMILES: CC1=CC(=O)OC2=CC(=C(C=C12)CN(C)CC(=O)O)O
Cayman Chemical 5Z 2E-CU-3 25mg
A DGK-α inhibitor (IC50 = 0.6 µM for the porcine enzyme); selective for DGK-α over other type I DGKs, as well as type II, type III, type IV, and type V DGKs (IC50s = 7-36 µM); induces apoptosis in HeLa and HepG2 cells and enhances concanavalin A-induced increases in IL2 mRNA expression in Jurkat T cells at 5 µM
Cayman Chemical 5Z 2E-CU-3 10mg
A DGK-α inhibitor (IC50 = 0.6 µM for the porcine enzyme); selective for DGK-α over other type I DGKs, as well as type II, type III, type IV, and type V DGKs (IC50s = 7-36 µM); induces apoptosis in HeLa and HepG2 cells and enhances concanavalin A-induced increases in IL2 mRNA expression in Jurkat T cells at 5 µM
Medchemexpress LLC (5Z,2E)-CU-3 | 1815598-71-0 | 95.0% | 1 ML
(5Z,2E)-CU-3 is a small-molecule diacylglycerol kinase (DGK) inhibitor and apoptosis inducer supplied as a ready-to-use 10 mM solution in DMSO for research applications.
- Supplied as a 10 mM solution in DMSO (1 mL).
- High purity verified at 95.0%.
- Molecular weight 392.47 g/mol and formula C16H12N2O4S3.
- Solid, yellow to brown appearance.
- Intended for apoptosis and DGK pathway research.
Medchemexpress LLC p-Coumaric acid ethyl ester | 7362-39-2 | MFCD00210460 | 50 MG
p-Coumaric Acid Ethyl Ester is a non-competitive, reversible inhibitor of tyrosinase. It quenches the intrinsic fluorescence of the enzyme and changes the binding affinity of L-tyrosine by inducing conformational changes in the catalytic domain of tyrosinase, without binding to the copper ion of the enzyme. This compound is utilized in the development of medicines, cosmetics, and for fruit preservation.
- Non-competitive, reversible inhibitor of tyrosinase
- Quenches the intrinsic fluorescence of the enzyme
- Induces conformational changes in the catalytic domain of tyrosinase without binding to copper ion
- Exhibits anti-platelet activity in rabbit platelet-rich plasma
- Utilized in medicine and cosmetic development
- Used for fruit preservation
Medchemexpress LLC p-Coumaric Acid Ethyl Ester | 7362-39-2 | 1 ML
p-Coumaric Acid Ethyl Ester, also known as Ethyl (E)-p-hydroxycinnamate or Ethyl trans-4-hydroxycinnamate, is a reversible, non-competitive inhibitor of tyrosinase. It quenches the enzyme's intrinsic fluorescence and alters the binding affinity of L-tyrosine by inducing conformational changes in the catalytic domain, without binding to the copper ion. This compound finds application in the development of various products, including medicines, cosmetics, and fruit preservation products that utilize pollen.
- Non-competitive and reversible tyrosinase inhibitor.
- Changes L-tyrosine binding affinity through conformational changes in tyrosinase's catalytic domain.
- Does not bind to the copper ion of the enzyme.
- Applicable in developing medicines.
- Used in cosmetic formulations.
- Utilized in fruit preservation products.
Medchemexpress LLC (-)-Gallocatechin | 3371-27-5 | 306.27 | 5 MG
(-)-Gallocatechin is an epimer of (-)-Epigallocatechin (EGC) found in various tea products. It demonstrates antioxidant activity in vitro by inhibiting LDL oxidation and scavenging DPPH radicals.
- Inhibits production of thiobarbituric acid-reactive substances (TBARS) in Cu+2 mediated oxidation of human LDL.
- Exhibits antioxidant activity in the Ferric reducing-antioxidant power (FRAP) assay.
- Shows DPPH radical scavenging activity.
Medchemexpress LLC p-Coumaric Acid Ethyl Ester | 7362-39-2 | 25 MG
p-Coumaric Acid Ethyl Ester is a non-competitive, reversible inhibitor of tyrosinase, utilized in the development of medicines, cosmetics, and fruit preservation products. It boasts a purity of 99.19% and a molecular weight of 192.21, presenting as a light yellow to light brown solid. This compound also exhibits anti-platelet activity.
- Non-competitive, reversible tyrosinase inhibitor
- IC50 of 4.89 μg/mL and Ki of 1.83 μg/mL against tyrosinase
- Quenches intrinsic fluorescence of the enzyme
- Alters L-tyrosine binding affinity through conformational changes in tyrosinase
- Does not bind to the enzyme's copper ion
- Shows anti-platelet activity in rabbit platelet-rich plasma (IC50 = 130.4 μM)
- Soluble in DMSO at 100 mg/mL
Medchemexpress LLC p-Coumaric Acid Ethyl Ester | 7362-39-2 | 100 MG
p-Coumaric Acid Ethyl Ester is a non-competitive, reversible inhibitor of tyrosinase, used in the development of medicines, cosmetics, and fruit preservation products derived from pollen. It functions by quenching the intrinsic fluorescence of the enzyme and inducing conformational changes in the catalytic domain of tyrosinase, which alters the binding affinity of L-tyrosine without binding to the copper ion.
- Tyrosinase inhibition: Non-competitive, reversible inhibitor with IC50 = 4.89 μg/mL and Ki = 1.83 μg/mL
- Shows anti-platelet activity in rabbit platelet-rich plasma (IC50 = 130.4 μM)
- Used in the development of medicines, cosmetics, and fruit preservation products
- High purity of 99.19%
- Molecular weight: 192.21
- Chemical formula: C11H12O3
- Appearance: Solid, light yellow to light brown
- Soluble in DMSO at 100 mg/mL (520.26 mM)