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Commonly in liquid form and available in various chemical compositions, solvents are substances that dissolve solutes to form solutions. The amount and type of solute that a solvent can dissolve is dependent upon temperature and polarity.
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Trametinib-d4 is the deuterium labeled Trametinib. Trametinib is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of about 2 nM. It activates autophagy and induces apoptosis.
Can be used as a tracer.
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules for quantitation.
Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
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Mavacamten-d5 is a deuterium-labeled version of Mavacamten (HY-109037), an orally active modulator of cardiac myosin. This compound is intended for research use only.
Can be used as a tracer.
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Stable heavy isotopes are incorporated into drug molecules for quantitation during drug development.
Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
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Fmoc-leucine-d3 is a white to off-white solid that has been tested and complies with given specifications. It is consistent with structure based on 1H NMR Spectrum and LCMS analysis.
Appearance: white to off-white solid
1H NMR Spectrum: consistent with structure
LCMS: consistent with structure
Isotopic enrichment: 99.86%
Storage: powder at -20°C for 3 years, 4°C for 2 years; in solvent at -80°C for 6 months, -20°C for 1 month
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Glutaric acid-d4 is a deuterium-labeled form of Glutaric acid. Glutaric acid is a C5 dicarboxylic acid that plays a role as an intermediate in the catabolic pathways of lysine and tryptophan. It has been observed to influence pericyte contractility and migration. Additionally, Glutaric acid is recognized as an indicator for glutaric aciduria type I. This product is intended for research use only.
Used as a tracer in research applications.
Suitable as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
Heavy isotopes like deuterium can impact the pharmacokinetic and metabolic profiles of pharmaceutical compounds.
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Methyl yellow-d5 (N,N-dimethyl-4-(phenyldiazenyl)aniline-d5) is the deuterium-labeled isotopologue of methyl yellow supplied as a high-purity analytical reference standard. It is intended for use as a tracer or internal standard in mass spectrometry and other analytical workflows, and is provided with high isotopic enrichment and defined storage recommendations.
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(±)12(13)-EpOME-d4 is a deuterium labeled compound designed for research use. It can serve as a tracer and an internal standard in quantitative analysis methods such as NMR, GC-MS, or LC-MS. Deuteration may influence the pharmacokinetic and metabolic profiles of drugs.
Used as a tracer
Functions as an internal standard for quantitative analysis
Applicable in NMR, GC-MS, or LC-MS
Deuterium labeled compound
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L-alloisoleucine-d10 is the deuterium-labeled (d10) isotopologue of L-alloisoleucine supplied as an analytical reference standard for isotope-dilution and mass spectrometry applications. It retains the stereochemistry of L-alloisoleucine while providing a mass-shifted internal standard for accurate quantitation in biological and analytical workflows.
Deuterium labeled isotopologue for use as an internal standard.
Suitable for mass spectrometry and isotope-dilution assays.
Supplied in small, accurately weighed packs for analytical use.
Stable under recommended storage; consult certificate of analysis for purity and handling.
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