Monoterpenoids
Medchemexpress LLC Loganin | 18524-94-2 | 390.38 | 100 MG
Loganin is an iridoid glycoside compound with anti-inflammatory, antioxidant, and antitumor properties. It offers protective effects against acute lung injury and pulmonary fibrosis by upregulating the Nrf2/HO-1 signaling pathway. It also reduces neuroinflammation caused by spinal cord injury.
- Protects against acute lung injury
- Offers protection from pulmonary fibrosis
- Reduces neuroinflammation
- Upregulates Nrf2/HO-1 signaling pathway
Medchemexpress LLC Loganin | 18524-94-2 | 390.38 | 50 MG
Loganin is an iridoid glycoside compound with anti-inflammatory, antioxidant, and antitumor properties. It offers protective effects against acute lung injury and pulmonary fibrosis. Loganin protects against LPS-mediated inflammation and oxidative stress by upregulating the Nrf2/HO-1 signaling pathway, and it reduces neuroinflammation caused by spinal cord injury (SCI).
- Anti-inflammatory, antioxidant, and antitumor properties
- Protects against acute lung injury and pulmonary fibrosis
- Upregulates nrf2/HO-1 signaling pathway
- Reduces neuroinflammation caused by spinal cord injury
- High purity
- White to off-white solid appearance
Medchemexpress LLC Catalpol | 2415-24-9 | 362.33 | 1 ML
Catalpol, also known as Catalpinoside, is an iridoid glycoside identified in *Rehmannia glutinosa*. This compound is primarily used as a laboratory chemical for the manufacture of substances and is intended for research purposes.
- Exhibits neuroprotective effects
- Shows hypoglycemic activity
- Possesses anti-inflammatory properties
- Demonstrates anti-cancer effects
- Acts as an anti-spasmodic agent
- Functions as an anti-oxidant
- Has anti-HBV effects
- Suitable for laboratory research
Medchemexpress LLC Aucubin | 479-98-1 | 346.33 | 1 ML
Aucubin is an iridoid glycoside component found in E. ulmoides that can cross the blood-brain barrier (BBB). It exhibits anti-anxiety, antidepressive, and anti-neuroinflammatory effects.
- Possesses antioxidant, anti-aging, and anti-inflammatory properties
- Exhibits antimicrobial, anti-fibrotic, and anti-cancer activities
- Offers hepatoprotective, neuroprotective, and osteoprotective benefits
- Intended for research use only
Medchemexpress LLC HY-N0807 5mg Medchemexpress, Swertiamarin CAS:17388-39-5 Purity:>98%
Medchemexpress, HY-N0807 5mg Swertiamarin CAS:17388-39-5 Swertiamarin, a secoiridoid glycoside found in genera of Enicostemma Species, confers anti-hyperglycemic and anti-hyperlipidemic effects. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC Geniposide 24512-63-8 100mg
Geniposide (24512-63-8) is an iridoid glycoside designed to modulate oxidative stress responses by activating and promoting the nuclear translocation of the Nrf2 transcription factor thereby upregulating downstream antioxidant enzyme expression Geniposide exerts its biological activity primarily through Nrf2-mediated pathways In in vitro studies geniposide inhibits tumor cell proliferation and induces apoptosis with reported IC50 values ranging from approximately 20 80 M depending on the cancer cell line Based on these pharmacological properties geniposide holds research potential in neuroprotection cancer biology and metabolic disorder studies including investigation of glucose metabolism and insulin sensitivity
Medchemexpress LLC Genipin 1-gentiobioside | 29307-60-6 | 99.7% | 550.51 g/mol | C23H34O15 | 10 MG
Genipin 1-gentiobioside is an iridoid glycoside isolated from Gardenia jasminoides, provided as a research reagent for biological and pharmacological studies. It is commonly used in bioactivity screening and analytical applications due to its reported hepatoprotective, anti-inflammatory, antioxidant, and antithrombotic properties.
- High purity suitable for analytical and bioassay applications.
- Reported bioactivities including hepatoprotective, anti-inflammatory, antioxidant, and antithrombotic effects.
- Characterized by CAS 29307-60-6, molecular formula C23H34O15, molecular weight 550.51 g/mol.
- Supplied in small vials to support screening and method development workflows.
Apexbio Technology LLC Genipin 6902-77-8 10mM (in 1mL DMSO)
Genipin (CAS 6902-77-8) is a natural small molecule isolated from Gardenia fruit traditionally employed in Chinese medicine for managing type 2 diabetes symptoms It demonstrates antiviral activity against hepatitis C virus exhibiting an IC50 of 88 41 M In vitro studies show Genipin enhances glucose uptake in C2C12 myotubes by increasing GLUT4 translocation intracellular ATP and calcium levels via ATP-sensitive potassium channel closure with dependence on PI3-K and calcium signaling pathways Additionally in rat liver models Genipin enhances Mrp2-mediated bile secretion and transporter localization without altering Mrp2 mRNA
AdipoGen Genipin
Chemical. CAS 6902-77-8. Formula C11H14O5. MW 226.2. Isolated from Gardenia jasminoides Ellis fruits. Cell permeable inhibitor of uncoupling protein 2 UCP2. Increases glucose-stimulated insulin secretion, mitochondrial membrane potential and ATP levels in pancreatic island cells. Anticancer, antimetastatic and anti-angiogenic agent. Increases Bax/Bcl-2 ratio and induces PARP cleavage and caspase-3- and caspase-9-mediated apoptosis in non-small cell lung cancer NSCLC cells. Sensitizes multidrug-resistant cancer cells to cytotoxic agents through UCP2 inhibition. Suppresses the tumor promoting function of UCP2 in a cellular model of Warburg effect. Anti-inflammatory agent. Upregulates nNOS neuronal nitric oxide synthase/NOS I and decreases acute inflammation through inhibition of LPS-induced NF-kappaB activity. Inhibits toll-like receptor TLR signaling and the production of pro-inflammatory cytokines, preventing sepsis and increasing survival in animal models of infection.
Cayman Chemical Genipin Inhibitors
A protein cross-linking agent isolated from G. jasminoides Ellis; inhibits UCP2 activity; 5 µM genipin increases glucose-stimulated insulin secretion in isolated pancreatic islets chronically exposed to high levels of glucose; induces apoptosis in FaO rat hepatoma cells and human hepatocarcinoma Hep3B cells
eMolecules Medchem Express / Genipin 1--D-gentiobioside / 5mg / 482204605 / HY-N2094 / / 29307-60-6 / MFCD12031626 / 550.510 / C23H34O15
Medchem Express / Genipin 1--D-gentiobioside / 5mg / 482204605 / HY-N2094 / / 29307-60-6 / MFCD12031626 / 550.510 / C23H34O15
Cayman Chemical GenIpIn 1-gentIobIosIde 500ug
An iridoid glycoside; inhibits AChE by 60.23% at 25 UG/ml; is cytotoxic to BRL 3A rat liver fibroblasts from 50-500 UG/ml; inhibits the germination of G. jasminoides and N. offinicale seeds and the growth of B. rapa roots; prevents scopolamine-induced increases in escape latency in the Morris water maze in mice at 2.5 mg/kg
eMolecules Medchem Express / Ajugol / 5mg / 446275542 / HY-N0914 / / 52949-83-4 / MFCD28902296 / 348.348 / C15H24O9
Medchem Express / Ajugol / 5mg / 446275542 / HY-N0914 / / 52949-83-4 / MFCD28902296 / 348.348 / C15H24O9
Apexbio Technology LLC Catalpol 2415-24-9 20mg
Catalpol (2415-24-9) is a small-molecule modulator targeting adrenal cortical cells It is designed to stimulate steroidogenic pathways thereby promoting androgen hormone secretion Catalpol exerts its biological activity primarily through upregulation of steroid biosynthesis and inhibition of inflammatory mediators In in vitro experiments evaluating steroid hormone biosynthesis catalpol demonstrates an inhibitory activity profile against inflammatory mediators with an IC50 value ranging approximately from 10 to 50 M depending on assay conditions and cell models used Based on these pharmacological properties catalpol holds research potential in adrenal cortex function studies regulation of androgen synthesis pathways and investigations of anti-inflammatory mechanisms
Cayman Chemical SynthetIc GenIposIde 100mg
An iridoid glycoside with diverse biological activities; reduces exudate volume and nitrite levels in a rat model of carrageenan-induced air pouch inflammation at 0.1 mg/pouch; prevents prevents carrageenan-induced paw edema in rats at 100 mg/kg, p.o.; reduces serum levels of ALT and AST and hepatic levels of MDA as well as decreases in hepatic levels of SOD and GPX in a rat model of high-fat diet-induced NASH at 50 and 100 mg/kg; prevents increases in apoptosis and decreases in the number of dopaminergic neurons in the substantia nigra in a mouse model of MPTP-induced Parkinson's disease at 100 mg/kg; improves motor coordination in the rotarod and swim tests in a rat model of Parkinson's disease