Quinone and hydroquinone lipids
Medchemexpress LLC Rel-PROTAC PARP1 degrader | 99.0% | 1145.09 | 25 MG
rel-PROTAC PARP1 degrader is the relative configuration of ROTAC PARP1 degrader (HY-114324). ROTAC PARP1 degrader is a PARP1 degrader based on MDM2 E3 ligand. It induces significant PARP1 cleavage and programmed cell death. PROTAC PARP1 degrader at 10 μM at 24 h inhibits MDA-MB-231 cell line with an IC50 of 6.12 μM.
- Relative configuration of ROTAC PARP1 degrader
- Based on MDM2 E3 ligand
- Induces significant PARP1 cleavage
- Induces programmed cell death
- Inhibits MDA-MB-231 cell line with an IC50 of 6.12 μM at 10 μM (24 h)
- Purity: 98.99%
- Molecular weight: 1145.09
- Appearance: Solid
- Color: White to off-white
- Soluble in DMSO (110 mg/mL)
Cambridge Isotope Laboratories Vitamin B1 pyrophosphate chloride (pyrimidyl-methyl-D3 98%) CP 95% 1 mg
Vitamin B1 pyrophosphate chloride (pyrimidyl-methyl-D3 98%) CP 95% 1 mg
Medchemexpress LLC Actinine-d9 chloride | 85806-17-3 | 98.0% | 190.72 | 1 MG
Actinine-d9 chloride is the deuterium labeled Actinine chloride. Actinine chloride is an angiopathic substance produced as an intermediary metabolite by gut microbiota that feed on carnitine in dietary red meat. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Contains a stable heavy isotope.
Cayman Chemical PentnoIc AcId-d9 100mg
An internal standard for the quantification of pentanoic acid by GC- or LC-MS
Selleck Chemical LLC Vitamin E S4686-1g
Vitamin E (D-alpha-Tocopherol) is a fat-soluble vitamin with potent antioxidant properties It is a potent peroxyl radical scavenger and inhibits noncompetitively cyclooxygenase activity in many tissues also inhibits angiogenesis and tumor dormancy through suppressing vascular endothelial growth factor (VEGF) gene transcription
Selleck Chemical LLC Vitamin E Acetate S3681-25mg
Vitamin E Acetate (Tocopherol) is the stable form of Vitamin E most often used in cosmetic formulations for its skin care benefits It protects the cells against free radicals and prevents the peroxidation of body fats as an in-vivo antioxidant Vitamin E Acetate (Tocopherol) is the stable form of Vitamin E most often used in cosmetic formulations for its skin care benefits It protects the cells against free radicals and prevents the peroxidation of body fats as an in-vivo antioxidant
Medchemexpress LLC ATIC-IN-1 acetate | 3067165-96-9 | C23H37N7O7 | 25 MG
ATIC-IN-1 acetate, also known as compound 14, is an inhibitor that targets the dimerization of Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). This dimerization is crucial for the AICAR transformylase activity of ATIC, which plays a role in de novo purine biosynthesis. It demonstrates anti-tumor activity by reducing cell numbers and cell division rates.
- Inhibits ATIC dimerization with a Ki value of 685 nM
- Exhibits anti-tumor activity
- Reduces cell numbers and cell division rates
- Can be used in research to study ATIC dimerization and its role in purine biosynthesis and tumor proliferation
- Inhibits the proliferation of MCF-7 cells at concentrations of 100-500 μM over 48 hours
- At 250 μM for 24-72 hours, it reduces cell division rather than increasing cell death
Medchemexpress LLC Pyridoxine (hydrochloride) | 58-56-0 | C8H12ClNO3 | 5 MG
Pyridoxine hydrochloride (Pyridoxol; Vitamin B6) is a pyridine derivative. It demonstrates antioxidant effects in a cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.
- Exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.
- Has protective potential against Alzheimer's disease.
- Attenuates reactive oxygen species levels.
- Decreases expression of cytoplasmic Nrf2.
- Upregulates whole-cell HO-1 expression.
Medchemexpress LLC Vitamin D Receptor Antibody | 10 UL
Vitamin D Receptor Antibody is a rabbit-derived and non-conjugated IgG polyclonal antibody, targeting the Vitamin D Receptor. It is for research use only.
- Immunohistochemistry-Paraffin (IHC-P): 1:100-500 dilution ratio
- Immunohistochemistry-Frozen (IHC-F): 1:100-500 dilution ratio
- Immunocytochemistry/Immunofluorescence (ICC/IF): 1:100-500 dilution ratio
Cambridge Isotope Laboratories Vitamin B2 (riboflavin) (13C4 99% 15N2 98%) CP 97% 1 mg
Vitamin B2 (riboflavin) (13C4 99% 15N2 98%) CP 97% 1 mg
Cayman Chemical cKItCD117 GnK Isoform EX
Source: Active recombinant human C-terminal His-tagged c-Kit GNNK−isoform extracellular domain expressed in HEK293 cells • Amino acids: 26-516 • MW: 56.7 kDa