Triterpenoids
Medchemexpress LLC Squalane (Standard) | 111-01-3 | 500 MG
Squalane, a saturated derivative of Squalene, is found in various natural sources including fish oils and certain vegetable oils. It is recognized for its diverse biological activities, encompassing anticancer, antioxidant, skin hydrating, and emollient properties. Research indicates its potential application as a drug carrier and detoxifying agent, with observed effects in both animal models and in vitro studies.
- Purity: 98.0%
- Molecular weight: 422.83
- Formula: C30H62
- Appearance: Colorless to light yellow liquid
- Sourced from animals (fish oils)
- Storage: Pure form -20°C for 3 years, 4°C for 2 years; in solvent -80°C for 6 months, -20°C for 1 month.
- Soluble in DMSO: 100 mg/mL
Cayman Chemical BetulInIc AcId 100mg
An agonist of the bile acid receptor TGR5 (EC50 = 1 µM) and blocks fatty liver development in cells and mice given ethanol; reduces NF-κB signaling and expression of miR-33 in LPS-treated macrophages, increasing levels of ABCA1; inhibits replication of HIV-1 (IC50 = 1.4 µM) and has cytotoxic effects against cancer cells
Research Products International Corp Forskolin, 1 Milligram
- CAS Number: 66575-29-9
- Molecular Formula: C22H34O7
- Molecular Weight: 410.5
Sigma Aldrich Fine Chemicals Biosciences Celastrol phyproof(R) Reference Substance | 34157-83-0 | MFCD03424073 | 10MG
Celastrol phyproof(R) Reference Substance | Purity: >=95.0% (HPLC) | Mol Wt: 450.61 | 34157-83-0 | MFCD03424073 | 10MG
Medchemexpress LLC HY-N2040 5mg Medchemexpress, (20R)-Protopanaxadiol CAS:7755-01-3 Purity:>98%
Medchemexpress, HY-N2040 5mg (20R)-Protopanaxadiol CAS:7755-01-3 (20R)-Protopanaxadiol is a triterpenoid saponin metabolite of 20(R)-ginsenoside Rg3 in black ginseng. (20R)-Protopanaxadiol exhibits anti-tumor activity and cytotoxicity, and potently inhibits the growth of Helicobacter pylori. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
AdipoGen Betulinic acid (>99%) (100 mg)
Chemical. CAS: 472-15-1. Formula: C30H48O3. MW: 456.7. Isolated from Platanus acerifolia bark. Anti-HIV compound. Anticancer compound. Apoptosis inducer. Modulator of NF-kappaB. Potent DNA topoisomerase II inhibitor. Potent proteasome activator. Antimalarial compound.
Sigma Aldrich Fine Chemicals Biosciences Squalene|111-02-4 | MFCD00008912 | 10ml
Squalene | 98% | 410.72 | 111-02-4 | MFCD00008912 | 10ml
Cayman Chemical BetulInIc AcId methyl esTR 1mg
A triterpenoid and an esterified version of betulinic acid with diverse biological activities; inhibits HIV-1 reverse transcriptase (IC50 = 11 μM); active against L. braziliensis and T. cruzi (IC50s = 69.9 and 93.3 μM, respectively); induces melanogenesis in (EC50 = 2.5 μM) and inhibits the growth of B16 2F2 melanoma cells in vitro (IC50 = 4.9 μM); cytotoxic to SK-LU-1, HepG2, HeLa, SK-MEL-2, and AGS cells (IC50s = 60.84, 77.43, 80.17, 66.17, and 69.94 μg/ml, respectively);
Apexbio Technology LLC Oleanolic acid(Synonyms: Oleanic acid, Caryophyllin, Astrantiagenin, Giganteumgenin, Caryophyllinic acid, 3β-Hydroxyolean-12-en-28-oic acid), 500mg, CAS: 508-02-1.
Oleanolic acid (CAS 508-02-1) is a naturally occurring triterpenoid isolated primarily from garlic and Phytolacca americana It exerts anti-HIV activity through induction of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) enzymes involved in inflammatory and immune responses Due to its mechanism of modulating these targets oleanolic acid serves as a valuable compound in biomedical research aimed at exploring novel antiviral strategies and immune pathway modulation
Cayman Chemical 18-GlycyrrhetInIc AcId 5g
A major metabolite of glycyrrhizin, a constituent of licorice that exhibits anti-ulcerative, anti-inflammatory, and immunomodulatory properties; at 100 mg/kg/day, reduces lipid peroxidation and increases antioxidant activity in diabetic rats; suppresses LPS-induced TNF-α production and NF-κB activation in mouse macrophages 100-200 μM
Apexbio Technology LLC Betulinic acid(Synonyms: Betulic acid, 3β-Hydroxy-lup-20(29)-en-28-oic acid, Lupatic acid, Betulonic acid), 500mg, CAS: 472-15-1.
Betulinic acid (CAS 472-15-1) is a pentacyclic triterpenoid obtained from natural sources exhibiting pharmacological properties relevant to oncology and infectious diseases research It induces apoptosis selectively in tumor cells by engaging mitochondrial apoptotic pathways independently of both p53 and CD95 signaling Additionally betulinic acid functions as an agonist for the bile acid receptor TGR5 demonstrating activity with an EC50 of approximately 1 04 M Due to its apoptotic effects and antiviral properties betulinic acid is extensively utilized in preclinical studies exploring cancer therapeutics and anti-HIV strategies
AdipoGen Forskolin, 66428-89-5, MFCD00082317, 25 mg
MF: C22H34O7, MW: 410.5, ≥99%, Appearance: White to off-white solid. Potent, cell permeable adenylyl cyclase activator. Increases intracellular cAMP levels. Widely used tool to investigate cAMP as a second messenger. Inotropic and antihypertensive. Smooth muscle relaxant/vasodilator.
Apexbio Technology LLC Limonin 1180-71-8 200mg
Limonin (CAS 1180-71-8) is a natural limonoid with inhibitory activities against carcinogenesis and HIV-1 replication It modulates apoptotic signaling pathways to induce apoptosis and suppress HIV-1 replication In in vitro studies limonin demonstrates dose-dependent inhibition of HIV-1 replication with an EC50 of approximately 60 M in human peripheral blood mononuclear cells (PBMCs) and monocyte/macrophage (M/M) cells In human hepatoma HepG2 cells limonin induces apoptosis by affecting relevant signaling pathways Animal studies show that limonin reduces tumor burden and incidence in DMBA-treated Syrian hamsters and inhibits colon adenocarcinoma development in azoxymethane (AOM)-treated rats Based on these pharmacological properties limonin holds research potential in HIV antiviral mechanisms and chemically-induced carcinogenesis models
Medchemexpress LLC HY-N0818 5mg Medchemexpress, Chikusetsusaponin Iva CAS:51415-02-2 Purity:>98%
Medchemexpress, HY-N0818 5mg Chikusetsusaponin Iva CAS:51415-02-2 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
TARGETMOL CHEMICALS INC LUPEOL 50MG
Also available in 5 mg 10 mg 25 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Lupeol (Monogynol B) is a novel androgen receptor inhibitor with anti-inflammatory and antioxidant activity. purity: 99%