Triterpenoids
Enzo Life Sciences Betulinic acid (~95%) (1g). CAS: 472-15-1
Antitumor and anti-HIV agent. Induces apoptosis by activating mitochondrial permeability transition (MPT). Inhibits NF-κB activation and NF-κB-regulated gene expression induced by carcinogens and inflammatory stimuli. Decreases expression of Bcl-2 and cyclin D1. Potent proteasome activator. Alternative name: 3beta-Hydroxy-20(29)-lupaene-28-oic acid. Purity: ≥90% (HPLC). Appearance: White to off-white powder. Solubility: Soluble in DMSO. Long Term Storage: +4°C.
Selleck Chemical LLC Betulinic acid S3603-100mg
Betulinic acid (ALS-357 Lupatic acid Betulic acid) a pentacyclic triterpenoid from Syzigium claviflorum is a inhibitor of HIV-1 with EC50 of 1 4 M It s reported that Betulinic acid acts as a new inhibitor of NF- B Phase 1/2
Cayman Chemical GlycyrrhIzIc AcIdamonIum s 50g
A natural agonist of the human sweet taste receptor and used as a flavorant; has diverse cellular effects at low doses, including antioxidant, anti-inflammatory, antimicrobial, and antiviral actions
Cayman Chemical Betulinic acid 500MG
An agonist of the bile acid receptor TGR5 (EC50 = 1 µM) and blocks fatty liver development in cells and mice given ethanol; reduces NF-κB signaling and expression of miR-33 in LPS-treated macrophages, increasing levels of ABCA1; inhibits replication of HIV-1 (IC50 = 1.4 µM) and has cytotoxic effects against cancer cells
Selleck Chemical LLC Glycyrrhetinic acid
Glycyrrhetinic acid is a triterpenoid aglycone component of the natural product glycyrrhizinic acid and possesses remarkable anti-proliferative and apoptosis-inducing activity in various cancer cell lines
Apexbio Technology LLC Oleanolic acid(Synonyms: Oleanic acid, Caryophyllin, Astrantiagenin, Giganteumgenin, Caryophyllinic acid, 3β-Hydroxyolean-12-en-28-oic acid), 100mg, CAS: 508-02-1.
Oleanolic acid (CAS 508-02-1) is a naturally occurring triterpenoid isolated primarily from garlic and Phytolacca americana It exerts anti-HIV activity through induction of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) enzymes involved in inflammatory and immune responses Due to its mechanism of modulating these targets oleanolic acid serves as a valuable compound in biomedical research aimed at exploring novel antiviral strategies and immune pathway modulation
AdipoGen Forskolin, 66428-89-5, MFCD00082317, 1 mg
MF: C22H34O7, MW: 410.5, ≥99%, Appearance: White to off-white solid. Potent, cell permeable adenylyl cyclase activator. Increases intracellular cAMP levels. Widely used tool to investigate cAMP as a second messenger. Inotropic and antihypertensive. Smooth muscle relaxant/vasodilator.
Medchemexpress LLC Betulinic acid (standard) | 472-15-1 | MFCD00009619 | 99.2% | 456.70 | C30H48O3 | 50 MG
Betulinic acid (analytical standard) is a high-purity pentacyclic triterpenoid supplied for research and analytical applications. Supplied as a 50 mg solid with accompanying certificate of analysis and safety documentation, it is intended for use as a calibration standard and positive control in chromatographic and quantitative assays.
- High purity suitable for analytical use.
- Supplied as a solid 50 mg standard.
- Provided with COA and SDS for traceability.
- Suitable as a calibration standard or reference material.
- Applicable for chromatography, method development, and quantitative analysis.
Apexbio Technology LLC Limonin 1180-71-8 10mM (in 1mL DMSO)
Limonin (CAS 1180-71-8) is a natural limonoid with inhibitory activities against carcinogenesis and HIV-1 replication It modulates apoptotic signaling pathways to induce apoptosis and suppress HIV-1 replication In in vitro studies limonin demonstrates dose-dependent inhibition of HIV-1 replication with an EC50 of approximately 60 M in human peripheral blood mononuclear cells (PBMCs) and monocyte/macrophage (M/M) cells In human hepatoma HepG2 cells limonin induces apoptosis by affecting relevant signaling pathways Animal studies show that limonin reduces tumor burden and incidence in DMBA-treated Syrian hamsters and inhibits colon adenocarcinoma development in azoxymethane (AOM)-treated rats Based on these pharmacological properties limonin holds research potential in HIV antiviral mechanisms and chemically-induced carcinogenesis models
Enzo Life Sciences Betulinic acid (~95%) (500mg). CAS: 472-15-1
Antitumor and anti-HIV agent. Induces apoptosis by activating mitochondrial permeability transition (MPT). Inhibits NF-κB activation and NF-κB-regulated gene expression induced by carcinogens and inflammatory stimuli. Decreases expression of Bcl-2 and cyclin D1. Potent proteasome activator. Alternative name: 3beta-Hydroxy-20(29)-lupaene-28-oic acid. Purity: ≥90% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: +4°C.
Carbosynth LLC. FORSKOLIN 1000 MG
Forskolin | Molecular Weight: 410.5 g/mol | 66575-29-9 | MFCD00082317 | 1000 mg
Cayman Chemical GlycyrrhIzIc AcIdamonIum s 5g
A natural agonist of the human sweet taste receptor and used as a flavorant; has diverse cellular effects at low doses, including antioxidant, anti-inflammatory, antimicrobial, and antiviral actions
Medchemexpress LLC HY-10529 100mg Medchemexpress, Betulinic acid CAS:472-15-1 Purity:>98%
Medchemexpress, HY-10529 100mg Betulinic acid CAS:472-15-1 Betulinic acid is a natural pentacyclic triterpenoid, acts as a eukaryotic topoisomerase I inhibitor, with an IC50 of 5 μM, and possesses anti-HIV, anti-malarial, anti-inflammatory and anti-tumor properties[3][4]. Betulinic acid acts as a new activator of NF-kB[5]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Betulinic acid | 472-15-1 | MFCD00009619 | 99.1% | 456.70 g/mol | C30H48O3 | 1 ML
Betulinic acid is a naturally occurring pentacyclic triterpenoid provided as a 10 mM solution in DMSO (1 mL) for laboratory research. It is commonly used in studies of apoptosis, cancer, inflammation, and autophagy due to its reported bioactivities.
- Natural pentacyclic triterpenoid with reported anticancer and apoptotic activity.
- Supplied as a 10 mM solution in DMSO for convenient handling and dosing.
- High purity (99.1%) suitable for analytical and biological assays.
- Available in multiple solid sizes for scale-up or formulation work.
- Intended for research use only.
Apexbio Technology LLC Betulinic acid(Synonyms: Betulic acid, 3β-Hydroxy-lup-20(29)-en-28-oic acid, Lupatic acid, Betulonic acid), 10mM (in 1mL DMSO), CAS: 472-15-1.
Betulinic acid (CAS 472-15-1) is a pentacyclic triterpenoid obtained from natural sources exhibiting pharmacological properties relevant to oncology and infectious diseases research It induces apoptosis selectively in tumor cells by engaging mitochondrial apoptotic pathways independently of both p53 and CD95 signaling Additionally betulinic acid functions as an agonist for the bile acid receptor TGR5 demonstrating activity with an EC50 of approximately 1 04 M Due to its apoptotic effects and antiviral properties betulinic acid is extensively utilized in preclinical studies exploring cancer therapeutics and anti-HIV strategies