Triterpenoids
Medchemexpress LLC 18α-Glycyrrhizic acid | 83896-44-0 | 50 MG
18α-Glycyrrhizic acid is a derivative of Glycyrrhizic acid. It exhibits weak antihepatotoxic and anti-inflammatory activities.
- Molecular weight: 822.93
- Formula: C42H62O16
- Appearance: Solid
- Color: White to off-white
- Structure classification: Ketones, aldehydes, acids
- Initial source: Plants, specifically Leguminosae, Glycyrrhiza glabra Linn.
- Purity: 99.79%
- In vitro solubility: DMSO: 100 mg/mL (121.52 mM; requires ultrasonic; hygroscopic DMSO significantly impacts solubility, use newly opened DMSO)
Medchemexpress LLC Limonin | 1180-71-8 | 99.1% | 470.51 | 100 MG
Limonin (Standard) is an analytical standard of Limonin, intended for research and analytical applications. It exhibits inhibitory effects against HIV-1 with an EC50 of 60.0 μM and induces apoptosis in human colon adenocarcinoma cells with an IC50 of 54.74 μM. Limonin is recognized for its antiviral and antitumor activities. This product is commonly utilized in qualitative, quantitative, and methodological research experiments involving techniques such as HPLC, GC, and MS, serving as a reference standard supplied for assay purposes.
- Antiviral activity: Inhibits HIV-1.
- Antitumor activity: Induces apoptosis in human colon adenocarcinoma cells.
- Research grade: Intended for research and analytical applications.
- Analytical standard: Serves as a reference standard for assays.
- Versatile application: Commonly used in HPLC, GC, and MS research experiments.
Medchemexpress LLC Betulinic acid (standard) | 472-15-1 | MFCD00009619 | 99.2% | 456.70 | C30H48O3 | 50 MG
Betulinic acid (analytical standard) is a high-purity pentacyclic triterpenoid supplied for research and analytical applications. Supplied as a 50 mg solid with accompanying certificate of analysis and safety documentation, it is intended for use as a calibration standard and positive control in chromatographic and quantitative assays.
- High purity suitable for analytical use.
- Supplied as a solid 50 mg standard.
- Provided with COA and SDS for traceability.
- Suitable as a calibration standard or reference material.
- Applicable for chromatography, method development, and quantitative analysis.
Medchemexpress LLC Lupeol acetate | 1617-68-1 | MFCD00017362 | 98.0% | 468.75 g/mol | C32H52O2 | 10MG
Lupeol acetate is a triterpenoid acetate supplied as an analytical research standard for use in chemical and biological research. It serves as a reference material for analytical assays and research into anti-inflammatory, antibacterial, and anticancer activities. A certificate of analysis is provided for batch-specific storage and handling recommendations.
- CAS number 1617-68-1
- Chemical formula C32H52O2
- Molecular weight 468.75 g/mol
- Purity 98.0% (NMR)
- Intended for use as an analytical standard and reference material
- Certificate of analysis available for batch-specific storage and handling
Selleck Chemical LLC Betulinic acid S3603-10mg
Betulinic acid (ALS-357 Lupatic acid Betulic acid) a pentacyclic triterpenoid from Syzigium claviflorum is a inhibitor of HIV-1 with EC50 of 1 4 M It s reported that Betulinic acid acts as a new inhibitor of NF- B Phase 1/2
Medchemexpress LLC Limonin | 1180-71-4 | >98% | 470.51 | 1 ML
Limonin is a natural product isolated from Dictamnus dasycarpus. It is known for its antiviral and antitumor activities, inhibiting HIV-1 and inducing apoptosis in human colon adenocarcinoma cells. In vitro studies show limonin's anti-proliferation effects on colon adenocarcinoma cells and pancreatic cancer cell lines, while in vivo research demonstrates its ability to significantly inhibit tumor growth in xenograft mouse models.
- Inhibits HIV-1 with an EC50 of 60.0 μM.
- Induces apoptosis in human colon adenocarcinoma cells with an IC50 of 54.74 μM.
- Shows anti-proliferation effects on Caco-2 and HCT-116 cells.
- Suppresses cell migration and invasion in HCT-116 cells.
- Activates Erk and p38 MAPK pathways.
- Significantly inhibits tumor growth in HCT-116 xenograft mouse models.
Medchemexpress LLC Oleanolic acid | 508-02-1 | 98.0% | 456.70 | 500 MG
Oleanolic acid (Caryophyllin) is a natural compound from plants with anti-tumor activities.
- Natural compound from plants.
- Exhibits anti-tumor activities.
Medchemexpress LLC Oleanolic acid 28-O-β-D-glucopyranoside | 14162-53-9 | 5 MG
Oleanolic acid 28-O-β-D-glucopyranoside is an orally active pentacyclic triterpenoid compound with anti-inflammatory effects. It inhibits inflammatory responses, enhances intestinal epithelial barrier function, and modulates gut microbiota in ulcerative colitis models. Its mechanism of action is related to the PI3K-AKT and MAPK signaling pathways and can be used in research for diseases such as colitis.
- Orally active pentacyclic triterpenoid compound with anti-inflammatory effects
- Inhibits inflammatory responses and modulates gut microbiota
- Enhances intestinal epithelial barrier function
- Targets IL-6 and COX-2 pathways
- Increases transepithelial electrical resistance (TEER) and tight junction protein expression in Caco-2 cells
- Reduces inflammatory cytokines (IL-6, TNF-α, COX-2, iNOS) in Caco-2 cells
- Ameliorates ulcerative colitis in mouse models by reducing inflammation and improving colon health
Selleck Chemical LLC Glycyrrhizin (NSC 167409) S2302-100mg
Glycyrrhizin (NSC 167409 Glycyrrhizic Acid) is a direct HMGB1(high mobility group box 1) inhibitor that inhibits HMGB1-dependent inflammatory molecule expression and oxidative stress modulates P38 and P-JNK but not p-ERK signalling Also inhibits 11 beta-hydroxysteroid dehydrogenase and monoamine oxidase (MAO)
Apexbio Technology LLC Limonin 1180-71-8 10mM (in 1mL DMSO)
Limonin (CAS 1180-71-8) is a natural limonoid with inhibitory activities against carcinogenesis and HIV-1 replication It modulates apoptotic signaling pathways to induce apoptosis and suppress HIV-1 replication In in vitro studies limonin demonstrates dose-dependent inhibition of HIV-1 replication with an EC50 of approximately 60 M in human peripheral blood mononuclear cells (PBMCs) and monocyte/macrophage (M/M) cells In human hepatoma HepG2 cells limonin induces apoptosis by affecting relevant signaling pathways Animal studies show that limonin reduces tumor burden and incidence in DMBA-treated Syrian hamsters and inhibits colon adenocarcinoma development in azoxymethane (AOM)-treated rats Based on these pharmacological properties limonin holds research potential in HIV antiviral mechanisms and chemically-induced carcinogenesis models
Cayman Chemical Betulinic acid 500MG
An agonist of the bile acid receptor TGR5 (EC50 = 1 µM) and blocks fatty liver development in cells and mice given ethanol; reduces NF-κB signaling and expression of miR-33 in LPS-treated macrophages, increasing levels of ABCA1; inhibits replication of HIV-1 (IC50 = 1.4 µM) and has cytotoxic effects against cancer cells
Apexbio Technology LLC Oleanolic acid(Synonyms: Oleanic acid, Caryophyllin, Astrantiagenin, Giganteumgenin, Caryophyllinic acid, 3β-Hydroxyolean-12-en-28-oic acid), 100mg, CAS: 508-02-1.
Oleanolic acid (CAS 508-02-1) is a naturally occurring triterpenoid isolated primarily from garlic and Phytolacca americana It exerts anti-HIV activity through induction of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) enzymes involved in inflammatory and immune responses Due to its mechanism of modulating these targets oleanolic acid serves as a valuable compound in biomedical research aimed at exploring novel antiviral strategies and immune pathway modulation
Medchemexpress LLC HY-N0892 5mg Medchemexpress, AKBA CAS:67416-61-9 Purity:>98%
Medchemexpress, HY-N0892 5mg AKBA CAS:67416-61-9 AKBA (Acetyl-11-keto-β-boswellic acid) is an active triterpenoid compound from the extract of Boswellia serrate and a novel Nrf2 activator. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cayman Chemical 23-hydroxy BetulInIc AcId 25mg
A triterpenoid with anticancer activity; inhibits proliferation of K562, B16, and HeLa cells (IC50s = 39.9, 78.5, and 80 µM, respectively), as well as HUVECs (IC50 = 94.8 µM); halts the cell cycle at the S phase and induces apoptosis in K562 cells
Medchemexpress LLC Betulinic acid | 472-15-1 | MFCD00009619 | 456.7 g/mol | C30H48O3 | 10 MG
Betulinic acid is a natural pentacyclic triterpenoid supplied as an analytical reference for research and chromatographic assays. It is reported to act as a eukaryotic topoisomerase I inhibitor and has documented antiviral, anti-malarial, anti-inflammatory, and antitumor activities.
- Intended for analytical and reference use.
- Natural pentacyclic triterpenoid with reported antiviral and antitumor activity.
- Molecular formula C30H48O3.
- Molecular weight 456.7 g/mol.
- Available as 10 mM in DMSO (1 mL) or as solid reference materials for method development.
- Suitable as a positive control and reference standard in chromatographic assays.