Triterpenoids
Cayman Chemical BetulInIc Aldehyde 1mg
A triterpenoid with diverse biological activities; active against P. falciparum (IC50 = 6.5 μg/ml) and M. tuberculosis (MIC = 25 μg/ml) in vitro, as well as laboratory and clinical isolates of methicillin-resistant and -sensitive S. aureus (MICs = 128-512 and 8-512 μg/ml, respectively); inhibits dengue virus NS5 RNA-dependent RNA polymerase (IC50 = 6.1 μM) and inhibits dengue virus type 2 replication by 20 and 55% at 5 and 10 μg/ml, respectively; inhibits growth of leukemia, melanoma, neuroblastoma, and normal fibroblast cell lines (IC50s = 1.1-4.9, 9.6-10.6, 7.5-8.8, and 18.5 μM, respectively)
Cayman Chemical BetulInIc Aldehyde 5mg
A triterpenoid with diverse biological activities; active against P. falciparum (IC50 = 6.5 μg/ml) and M. tuberculosis (MIC = 25 μg/ml) in vitro, as well as laboratory and clinical isolates of methicillin-resistant and -sensitive S. aureus (MICs = 128-512 and 8-512 μg/ml, respectively); inhibits dengue virus NS5 RNA-dependent RNA polymerase (IC50 = 6.1 μM) and inhibits dengue virus type 2 replication by 20 and 55% at 5 and 10 μg/ml, respectively; inhibits growth of leukemia, melanoma, neuroblastoma, and normal fibroblast cell lines (IC50s = 1.1-4.9, 9.6-10.6, 7.5-8.8, and 18.5 μM, respectively)
Medchemexpress LLC Betulinic acid | 472-15-1 | MFCD00009619 | 456.7 g/mol | C30H48O3 | 10 MG
Betulinic acid is a natural pentacyclic triterpenoid supplied as an analytical reference for research and chromatographic assays. It is reported to act as a eukaryotic topoisomerase I inhibitor and has documented antiviral, anti-malarial, anti-inflammatory, and antitumor activities.
- Intended for analytical and reference use.
- Natural pentacyclic triterpenoid with reported antiviral and antitumor activity.
- Molecular formula C30H48O3.
- Molecular weight 456.7 g/mol.
- Available as 10 mM in DMSO (1 mL) or as solid reference materials for method development.
- Suitable as a positive control and reference standard in chromatographic assays.
Enzo Life Sciences Betulinic acid (~95%) (1g). CAS: 472-15-1
Antitumor and anti-HIV agent. Induces apoptosis by activating mitochondrial permeability transition (MPT). Inhibits NF-κB activation and NF-κB-regulated gene expression induced by carcinogens and inflammatory stimuli. Decreases expression of Bcl-2 and cyclin D1. Potent proteasome activator. Alternative name: 3beta-Hydroxy-20(29)-lupaene-28-oic acid. Purity: ≥90% (HPLC). Appearance: White to off-white powder. Solubility: Soluble in DMSO. Long Term Storage: +4°C.
Enzo Life Sciences Betulinic acid (~95%) (500mg). CAS: 472-15-1
Antitumor and anti-HIV agent. Induces apoptosis by activating mitochondrial permeability transition (MPT). Inhibits NF-κB activation and NF-κB-regulated gene expression induced by carcinogens and inflammatory stimuli. Decreases expression of Bcl-2 and cyclin D1. Potent proteasome activator. Alternative name: 3beta-Hydroxy-20(29)-lupaene-28-oic acid. Purity: ≥90% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: +4°C.
AdipoGen Forskolin,Chemical. CAS: 66428-89-5 and 66575-29-9
Forskolin, AdipoGen Life Sciences. Chemical. CAS: 66428-89-5 and 66575-29-9. Formula: C22H34O7. MW: 410.5. Isolated from Coleus forskohlii. Potent, cell permeable adenylyl cyclase activator. Increases intracellular cAMP levels. Widely used tool to investigate cAMP as a second messenger. Inotropic and antihypertensive. Smooth muscle relaxant/vasodilator. Glucose transporter inhibitor. Platelet aggregation inhibitor. Stimulates lipolysis in fat cells. Non-competitive nicotinic acetylcholine receptors inhibitor. MAP kinase inhibitor. Upregulates mitochondrial uncoupling protein (UCP) mRNA levels in brown adipose tissue. Autophagy inhibitor. Hedgehog signaling inhibitor. Has antiglaucoma potential. Promotes neuronal differentiation of NSCs.
AdipoGen Forskolin, 66428-89-5, MFCD00082317, 1 mg
MF: C22H34O7, MW: 410.5, ≥99%, Appearance: White to off-white solid. Potent, cell permeable adenylyl cyclase activator. Increases intracellular cAMP levels. Widely used tool to investigate cAMP as a second messenger. Inotropic and antihypertensive. Smooth muscle relaxant/vasodilator.
Apexbio Technology LLC Betulinic acid(Synonyms: Betulic acid, 3β-Hydroxy-lup-20(29)-en-28-oic acid, Lupatic acid, Betulonic acid), 10mM (in 1mL DMSO), CAS: 472-15-1.
Betulinic acid (CAS 472-15-1) is a pentacyclic triterpenoid obtained from natural sources exhibiting pharmacological properties relevant to oncology and infectious diseases research It induces apoptosis selectively in tumor cells by engaging mitochondrial apoptotic pathways independently of both p53 and CD95 signaling Additionally betulinic acid functions as an agonist for the bile acid receptor TGR5 demonstrating activity with an EC50 of approximately 1 04 M Due to its apoptotic effects and antiviral properties betulinic acid is extensively utilized in preclinical studies exploring cancer therapeutics and anti-HIV strategies
Selleck Chemical LLC Lupeol S3614-25mg
Lupeol (Clerodol Monogynol B Fagarasterol Farganasterol) is a significant lupane-type triterpene represented in the plant fungi and animal kingdoms with anticancer antiprotozoal chemopreventive and anti-inflammatory properties