Triterpenoids
Cayman Chemical 18β-Glycyrrhetinic Acid, Purity: ≥98%, CAS: 471-53-4, 1 g
A major metabolite of glycyrrhizin, a constituent of licorice that exhibits anti-ulcerative, anti-inflammatory, and immunomodulatory properties; at 100 mg/kg/day, reduces lipid peroxidation and increases antioxidant activity in diabetic rats; suppresses LPS-induced TNF-α production and NF-κB activation in mouse macrophages 100-200 μM
Medchemexpress LLC Oleanolic acid | 508-02-1 | 98.0% | 456.70 | 500 MG
Oleanolic acid (Caryophyllin) is a natural compound from plants with anti-tumor activities.
- Natural compound from plants.
- Exhibits anti-tumor activities.
Apexbio Technology LLC Limonin 1180-71-8 10mM (in 1mL DMSO)
Limonin (CAS 1180-71-8) is a natural limonoid with inhibitory activities against carcinogenesis and HIV-1 replication It modulates apoptotic signaling pathways to induce apoptosis and suppress HIV-1 replication In in vitro studies limonin demonstrates dose-dependent inhibition of HIV-1 replication with an EC50 of approximately 60 M in human peripheral blood mononuclear cells (PBMCs) and monocyte/macrophage (M/M) cells In human hepatoma HepG2 cells limonin induces apoptosis by affecting relevant signaling pathways Animal studies show that limonin reduces tumor burden and incidence in DMBA-treated Syrian hamsters and inhibits colon adenocarcinoma development in azoxymethane (AOM)-treated rats Based on these pharmacological properties limonin holds research potential in HIV antiviral mechanisms and chemically-induced carcinogenesis models
Cayman Chemical Betulinic Acid, Purity: ≥97%, CAS: 472-15-1, 500 mg
An agonist of the bile acid receptor TGR5 (EC50 = 1 µM) and blocks fatty liver development in cells and mice given ethanol; reduces NF-κB signaling and expression of miR-33 in LPS-treated macrophages, increasing levels of ABCA1; inhibits replication of HIV-1 (IC50 = 1.4 µM) and has cytotoxic effects against cancer cells
Apexbio Technology LLC Oleanolic acid(Synonyms: Oleanic acid, Caryophyllin, Astrantiagenin, Giganteumgenin, Caryophyllinic acid, 3β-Hydroxyolean-12-en-28-oic acid), 100mg, CAS: 508-02-1.
Oleanolic acid (CAS 508-02-1) is a naturally occurring triterpenoid isolated primarily from garlic and Phytolacca americana It exerts anti-HIV activity through induction of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) enzymes involved in inflammatory and immune responses Due to its mechanism of modulating these targets oleanolic acid serves as a valuable compound in biomedical research aimed at exploring novel antiviral strategies and immune pathway modulation
Cayman Chemical Glycyrrhizic Acid (ammonium salt), Purity: ≥80%, CAS: 53956-04-0, 5 g
A natural agonist of the human sweet taste receptor and used as a flavorant; has diverse cellular effects at low doses, including antioxidant, anti-inflammatory, antimicrobial, and antiviral actions
Medchemexpress LLC Limonin | 1180-71-8 | 99.4% | 470.51 | 100 MG
Limonin inhibits HIV-1 with an EC50 of 60.0 μM. It induces human colon adenocarcinoma cells apoptosis with an IC50 of 54.74 μM. Limonin possesses antiviral and antitumor activities, making it relevant for research in infection and cancer.
- Inhibits HIV-1.
- Induces apoptosis in human colon adenocarcinoma cells.
- Exhibits antiviral and antitumor activities.
- Targets HIV.
- Targets apoptosis.
- Targets endogenous metabolite.
- Targets cytochrome P450.
- Targets P-glycoprotein.
Medchemexpress LLC Squalene | 111-02-4 | 410.72 | 50 MG
Squalene is an intermediate product in the synthesis of cholesterol. It exhibits several pharmacological properties, including hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumor activities. It is for research use only.
- Decreases intracellular ROS level
- Prevents H2O2-induced oxidative injury
- Protects against oxidative DNA damage in MCF10A epithelial cells
- Increases high density lipoprotein-cholesterol and paraoxonase 1 in mice
- Decreases oxidative stress in mice
Cayman Chemical Glycyrrhizic Acid (ammonium salt), Purity: ≥80%, CAS: 53956-04-0, 10 g
A natural agonist of the human sweet taste receptor and used as a flavorant; has diverse cellular effects at low doses, including antioxidant, anti-inflammatory, antimicrobial, and antiviral actions
AdipoGen Betulinic acid 99
Chemical. CAS 472-15-1. Formula C30H48O3. MW 456.7. Isolated from Platanus acerifolia bark. Anti-HIV compound. Anticancer compound. Apoptosis inducer. Modulator of NF-kappaB. Potent DNA topoisomerase II inhibitor. Potent proteasome activator. Antimalarial compound.
Sigma Aldrich Fine Chemicals Biosciences Squalene >=98%, liquid | 111-02-4 | MFCD00008912 | 500ML
Squalene >=98%, liquid | Purity: >=98% | Mol Wt: 410.72 | 111-02-4 | MFCD00008912 | 500ML
Apexbio Technology LLC Betulinic acid(Synonyms: Betulic acid, 3β-Hydroxy-lup-20(29)-en-28-oic acid, Lupatic acid, Betulonic acid), 10mM (in 1mL DMSO), CAS: 472-15-1.
Betulinic acid (CAS 472-15-1) is a pentacyclic triterpenoid obtained from natural sources exhibiting pharmacological properties relevant to oncology and infectious diseases research It induces apoptosis selectively in tumor cells by engaging mitochondrial apoptotic pathways independently of both p53 and CD95 signaling Additionally betulinic acid functions as an agonist for the bile acid receptor TGR5 demonstrating activity with an EC50 of approximately 1 04 M Due to its apoptotic effects and antiviral properties betulinic acid is extensively utilized in preclinical studies exploring cancer therapeutics and anti-HIV strategies